Poor Flow Research Articles

Delayed cephalic arch rupture following balloon angioplasty

BackgroundVascular access care comes with its substantial cost that include but not limited to poor blood flow during dialysis, stenosis throughout the dialysis circuits, aneurysmal dilatation, clots formation and complete thrombosis. Acute cephalic arch rupture is not that uncommon but delayed rupture is rare presentation that was not discussed previously.Case presentationWe describe a case of a 70-year-old female with end-stage renal disease (ESRD) undergoing a fistulogram and angioplasty of cephalic arch stenosis that resulted in a small vessel rupture that was successfully treated with prolonged balloon inflation initially. Unfortunately, this was complicated with massive venous rupture after initiating hemodialysis. The diseased segment was successfully treated with covered stent placement. This paper review and discuss cephalic arch stenosis, clinical presentation, and available initial and bailout treatment strategies.ConclusionsPrimary management of cephalic arch rupture is a prolong-low pressure balloon angioplasty, with covered stent across the site of extravasation if persisted. This case depicted a delayed vascular rupture following hemodialysis in patient with previously controlled extravasation that necessities covered stent placement. No data in the literature suggested the time that is required to avoid dialysis and improve healing.

Improving the cold flow properties of biodiesel from waste cooking oil by ternary blending with bio‐based alcohols and diesel from direct coal liquefaction

AbstractThe utilization and popularization of biodiesel are always limited by its poor cold flow properties. Both bio‐based alcohol and diesel from direct coal liquefaction (DDCL) has potential to enhance the cold flow properties of biodiesel. In this study, ternary blends of waste cooking oil biodiesel (BWCO) with DDCL and bio‐based ethanol (ET) or 1‐butanol (BT) were conducted to improve the cold flow properties of biodiesel. The pour point (PP), cold filter plugging point (CFPP), and cloud point (CP) of BWCO‐ET, BWCO‐BT, and BWCO‐DDCL binary blends, and BWCO‐ET‐DDCL and BWCO‐BT‐DDCL ternary blends were comparatively assessed. Ternary phase diagrams were also applied to analyze the blending effect of the three components on the cold flow properties of biodiesel. Results showed that both DDCL, ET, and BT can remarkably enhance the cold flow properties of BWCO. When the ternary blends contain 20 vol.% BWCO and less than 40 vol.% ET or BT, DDCL together with ET or BT exerted positive effects on enhancing the low‐temperature flow properties of BWCO, especially on the CP and CFPP. For ternary blends in 20:10:70 blending ratio, BWCO‐BT‐DDCL exhibited the lowest PP, CFPP, and CP of −23, −19, and −17°C, respectively. The crystallization behavior and crystal morphology of blended fuels are also observed via a polarizing optical microscope, and find that DDCL together with BT in biodiesel can effectively retard the aggregation of large crystals and inhibit crystals growth.

Does context matter? Voluntary work in long-term care

Introduction: Increased voluntary work in long-term care (LTC) is encouraged in white papers in Norway as well as in many other western states. This is due to the growth in the number of service recipients and a subsequent economic burden for the state. Voluntary work in nursing homes and home care services take place in different spatial contexts, but little attention has been paid to how the different contexts may potentially influence the possibilities for voluntary work. The aim of this study is to obtain new knowledge of the significance of context in recruitment of volunteers in LTC. Method: A cross-sectional study was conducted among leaders in nursing homes and home services in 50 municipalities across all regions of Norway. Descriptive analysis was used. Results: According to the leaders, home care services had less voluntary work than nursing homes. Respondents from home care scored “poor flow of information” and “low interest in the municipality” as major hinderances, more so than respondents from nursing homes did. Discussion: Nursing homes typically have many residents under one roof following a similar schedule. Thus, volunteer-run activities are held more easily at set times and incorporated into the daily life of the institutions. On the other hand, home dwellers in home care stay in a more individualised setting with more autonomy and can opt out of activities that nursing home residents would normally join. Skill acquisition, networking and socializing are common motivations for volunteering, and a nursing home setting may be an easier context to obtain this. The governmental endeavour for increased voluntary work in LTC can be seen as an effort to meet expected rises in public expenditure. However, the realism can be debated due to substantial challenges on the future potential of volunteerism in LTC, especially in the home care context.

Numerical Simulation of Turbine Expander in Natural Gas Pressure Energy Power Generation System

In this paper, the numerical simulation method is used to study the aerodynamic characteristics of the runoff turbine expander, the key equipment in the natural gas pressure energy recovery power generation system. The geometric structure of the turbine expander under the condition of sub-high pressure natural gas expansion was designed and the flow characteristics of the internal flow field during its operation were obtained by numerical simulation. It is found that the expansion process of fluid in the runoff turbine expander mainly occurs in the guide vane channel and the inlet section of the rotor channel. The turbine expander designed in this paper can well meet the working requirements under design conditions, and the flow in the whole channel is good. When the flow channel in the moving impeller changes from radial to axial, the flow field is complex and there is a poor flow. The research results of this paper provide a reference for the design and optimization of runoff turbine expander in natural gas pressure energy power generation system.

A New Current to The Armamentarium: Is the CHA2DS2-Vasc-HS Score Predictive of Low Left Internal Mammary Artery (LIMA) Flow in Patients Underwent Coronary Bypass Surgery?

Left internal mammary artery (LIMA) grafts should be used in patients undergoing CABG. No other procedure results in patency equivalent to that of the left anterior descending coronary artery (LAD)-LIMA bypass graft. The CHA2DS2-Vasc-HS scoring system can be used to successfully predict CAD severity in stable CAD patients. We aimed to investigate the relationship between LIMA flow and the CHA2DS2-Vasc-HS score. A total of 684 patients, who underwent CABG surgery, were included in this study. Previous history of bypass surgery, emergency operations, patients with Leriche syndrome and patients with severe obstructive pulmonary and subclavian artery disease were excluded from our study. Patients with a LIMA flow that was suitable for bypass grafting, as determined during the intraoperative evaluation, were included in the low LIMA flow group, and the CHA2DS2-Vasc-HS score was calculated for all patients. Patients in the low LIMA flow group (Group 1) were older. The CHA2DS2-Vasc-HS score (P < 0.001), presence of mild or moderate COPD (P = 0.022), number of severely diseased vessels (P = 0.036), and BMI (P < 0.001) were independent predictors of poor LIMA flow. The cutoff value of the CHA2DS2-VASc-HS score for the prediction of poor LIMA flow was >5.5, with a sensitivity of 92.9% and specificity of 83.4% (AUC: 0.938, 95% Cl: 0.906 - 0.970, P < 0.001). A preoperative high CHA2DS2-Vasc-HS score can be used to predict low intraoperative LIMA flow. The CHA2DS2-Vasc-HS score is an easy-to-use and reliable estimation method and can be used as an additional preoperative of LIMA flow in patients undergoing CABG due to severe CAD.

Flow characteristics of hydrofluorocarbon gas hydrate slurries under various conditions in a loop tube

Gas hydrate slurries, which are prepared using solid hydrates and water, are effective secondary refrigerants with a high latent heat of fusion and could be used to reduce global warming. The effective application of these slurries requires knowledge of their flow characteristics in good and poor flow states. In the present work, the flow properties of R-134a and R-32 gas hydrate slurries circulating in a loop tube were investigated using the Rabinowitsch–Mooney equation to estimate the flow characteristics. When undergoing laminar flow, the slurries in a good flow state were pseudoplastic fluids. However, under conditions that induced poor flow, the slurries behaved as dilatant fluids. The relative viscosities of the slurries were estimated using Happel’s equation according to the apparent particle hold-up. In turbulent flow, both slurries in good flow state acted as pseudoplastic fluids and maintained good flow characteristics.

Evaluating consumer and clinical sleep technologies: an American Academy of Sleep Medicine update

Evaluating consumer and clinical sleep technologies: an American Academy of Sleep Medicine update

A molecular explanation of cardiovascular protection through abnormal cannabidiol: Involving the dysfunctional β-adrenergic and ATP-sensitive K+ channel activity in cardiovascular compromised preterm infants.

Growing cannabis efficacy, usage frequency, legal supply, and declining awareness of danger recently led to expanded United States cannabis exposure. In turn, cannabis use among elderly people over 50 has more than tripled in a decade and has contributed toward a positive association of cannabis use with pathological conditions, which include type II diabetes, metabolic syndrome, neurovascular and cardiovascular disease. Remarkably, all these outcome results are mediated by the involvement of the ATP-sensitive K+ channel. Cardiovascular compromise is a common syndrome in preterm infants that leads to incidence and death and has been distinguished by poor systemic flow or hypotension. Conditions of cardiovascular compromise include vasodysregulation and myocardial malfunction through dysfunctional β-adrenergic activity. To avoid organ hypoperfusion progressing to tissue hypoxia-ischemia, inotropic drugs are used. Many premature children, however, respond insufficiently to inotropic activity with adrenergic agonists. The clinical disturbance including myocardial dysfunction through the activation of the ATP-sensitive K+ channel is often involved and the comparative efficacy of the nonpsychotropic cannabinoid, abnormal cannabidiol(Abn-CBD) is not yet known. Therefore, our primary aim was to investigate the molecular exploration of the cannabinoid system specifically Abn-CBD in cardiovascular protection involving dysregulated KATP.

Prediction of random packing density and flowability for non-spherical particles by deep convolutional neural networks and Discrete Element Method simulations

Non-spherical particles can be found in many industrial processes. Unfortunately, scalar shape parameters are often insufficient to predict their complex behavior. Therefore, this study used convolutional neural networks (CNN), which are able to interpret abstract shape features to derive the flow and packing behavior. For training data generation, experimentally validated Discrete Element Method simulations of silo filling and discharge were conducted. The subsequent training of the neural network was achieved with extensive input data augmentation. The CNN was then applied for the investigation of common shapes like ellipsoids or frustums for validation. The trained network showed good accordance to literature and high predictive robustness. Finally, the CNN assessed various food grains and tablet shapes. The network predicted the densest packing and best flowability for rounded lentils, whereas long rice kernels showed poor flow behavior. For pharmaceutical tablets, rounded and hexagonal shapes were predicted to yield denser packings than plain cylinders.

Angiographic flow velocity predicts lower limb outcomes after endovascular therapy: Application of the frame count method.

Several factors related to lesion characteristics and endovascular therapy (EVT) procedures have been reported to affect primary patency after EVT. However, it is unknown why these factors were associated with primary patency. We hypothesized patency failure was related to poor blood flow in affected arteries. This retrospective study included 131 consecutive patients who had received EVT with bare metal stents for peripheral artery disease caused by femoropopliteal artery lesions. Based on the tertile post-EVT flow velocity of the superficial femoral artery (SFA), patients were divided into high (n = 43), middle (n = 44), and low (n = 44) flow velocity groups. Flow velocity was measured using the frame count method. We measured incidence of major adverse limb events (MALE), composed of target lesion revascularization (TLR), non-TLR, and major amputation. At a median follow-up period of 22.7 months, MALE had occurred in 7 (16.3%), 10 (22.7%), and 29 (65.9%) of patients from the high, middle, and low SFA flow velocity groups, respectively (p < 0.001). Kaplan-Meier analysis showed incidence of MALE was significantly higher in the patients of low SFA flow velocity (log-rank test χ2 = 38.8, p < 0.001). Multivariate analysis found low SFA flow velocity to be an independent predictor for MALE (hazard ratio: 4.42; 95% CI: 2.27 to 8.60; p < 0.001) as was ankle-brachial index. Post-EVT SFA flow velocity for femoropopliteal artery lesions treated with bare metal stents is an independent predictor of limb patency. The frame count method for assessing arterial flow velocity is convenient and has potential for wide applications in EVT.

Investigation of flow velocity in recipient perforator artery for a reliable indicator for the flap transfer with perforator to perforator anastomosis.

In flap transfer with perforator to perforator anastomosis (FTPPA), encountering poor pulsation and blood flow in a recipient perforator intraoperatively often makes FTPPA impossible. This study sought to identify color and spectral Doppler ultrasonography (CSDUS) parameters that can aid reliable preoperative selection of a recipient perforator artery. The study enrolled 38 patients with lower extremity lymphedema who underwent vascularized lymphatic tissue transfer with perforator to perforator anastomosis for physiological lymphatic flow reconstruction. In all cases, three candidate recipient perforators were searched in each lower extremities, and vessel diameter and peak systolic flow velocity (PSFV) were measured. The inclusion criteria for candidates were a vessel diameter of >0.5 mm and a PSFV of >10cm/s. These measures were compared with intraoperative findings, diameters and if there was pulsation and visible spurting evident. A total of 114 candidates were selected, and 52 of the candidates were dissected until suitable perforators were found. PSFV (cm/s) on CSDUS was ≥20.0 in 32 perforators (84.2%) and was 15.0-19.9 in 6 perforators (15.8%) in the group with pulsation and visible spurting evident, and 15.0-19.9 in one perforator (7.1%) and ≤ 14.9 in 13 perforators (92.9%) in the group without pulsation and visible spurting evident. There was a statistically significant correlation between preoperative PSFV and intraoperative pulsation and visible spurting evident after dissection (P=0.021 × 10-3 ). The flap survival rate was 92.1%. PSFV is an important preoperative determinant of the suitability of a recipient perforator artery for FTPPA.

Impact of the whey protein/casein ratio on the reconstitution and flow properties of spray-dried dairy protein powders

This study focuses on the impact of the whey protein/casein ratio (100/0, 79/21, 57/43, 35/65, and 12/88) on the physicochemical and functional characteristics of dairy protein powders. Spray-drying was performed in the following conditions: 200 °C inlet air temperature and 85 °C outlet air temperature. Physicochemical properties (particle size distribution, shape factors, moisture content, and water activity) of spray-dried powders were characterized to explain their reconstitutability, on the basis of the wettability, dispersibility, solubility indices, and their flowability, evaluated with the FT4 powder rheometer.Reconstitutability analyses revealed that solubility of dairy protein powders linearly varied with the whey protein/casein ratio. It was also highlighted that wettability and dispersibility determined with the standard methods were not relevant to evaluate the reconstitutability of investigated powders: in fact, all studied powders were non-wettable and non-dispersible according to the milk powder standards. This was likely to result from the low median particle size (between 10 and 30 μm) of powders produced by spray-drying at pilot-scale.The flowability of powders was evaluated as poor due to a high level of interparticular cohesion, which mainly derived from their small median particle size. The impact of protein composition on flowability was not statistically significant, despite a shape modification reflected by a decrease in particle sphericity upon casein proportion increase. The small particle size, leading to poor flow properties, overwhelmed the impact the whey protein/casein ratio, but a slight improvement of the flowability and a reduction of cohesion was induced by higher proportions of whey proteins.

Study of Different Crystal Habits of Aprepitant: Dissolution and Material Attributes

In the present study, aprepitant (APT) was selected to find its suitable crystal habit, which can improve its existing poor dissolution and manufacturing processability. Solvents were screened out for solubility analysis of APT and further crystal habit modification. Solid-state characterization studies like powder X-ray diffraction (PXRD), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and Fourier infrared spectroscopy (FTIR) distinguished that tabular crystal habit was generated from acetone (APT-AC) and long tabular crystal habit was generated from ethyl acetate (APT-EA). Kawakita analysis and powder flow property studies showed that APT-EA is cohesive, has poor flow property and low bulk density compared to APT-AC (p &lt; 0.05). Heckel plots reflected that APT-EA shows higher fragmentation and particle rearrangement during the initial stages as indicated by the higher intercept values. Higher slopes in APT-EA and APT-AC confirmed better plasticity but lower yield pressure in APT-AC proved good plastic deformation compared to APT-EA (p &lt; 0.05). The dissolution profile of the APT-EA was found to be better than that of APT-AC. Overall, it can be concluded that APT-AC crystal habit has a better flow rate, tensile strength, and plasticity whereas APT-EA has better dissolution.

Functional Properties of Banana Starch (Musa spp.) and Its Utilization in Cosmetics

Unripe banana fruit of Musa acuminata (Musa AAA; Hom Khieo) and Musa sapientum L. (Musa ABB; Namwa) growing in Chiang Rai (Thailand) were used for extraction. The yield of the starches was 16.88% for Hom Khieo (HK) and 22.73% for Namwa (NW) based on unripe peeled banana fruit. The amylose contents of HK and NW were 24.99% and 26.23%, respectively. The morphology of starch granules was oval shape with elongated forms for large granules and round shape for small granules. The HK and NW showed B-type crystalline structure and the crystallinities were 23.54% and 26.83%, respectively. The peak temperature of gelatinization was around 77 °C and the enthalpy change (ΔH) was 3.05 and 7.76 J/g, respectively. The HK and NW banana starches showed 1.27 ± 0.12 g/g and 1.53 ± 0.12 g/g water absorption capacity, and 1.22 ± 0.11 g/g and 1.16 ± 0.12 g/g oil absorption capacity, respectively. The swelling power of the banana starches was 17.23 ± 0.94 g/g and 15.90 ± 0.15 g/g, respectively, and the percentage of solubility in water showed 26.43 ± 2.50 g/g and 20.54 ± 0.94 g/g, respectively. The banana starches showed very poor flow character. The HK and NW starches have the potential to be used in powder base preparations with no effect on the sensory texture of the product at 15% w/w maximum.

Optimization of the Hollow Rectification Sill in the Forebay of the Pump Station Based on the PSO-GP Collaborative Algorithm

The layout of the pump station is easily affected by topography, site, and other factors, resulting in poor inlet flow patterns in the forebay, which seriously affect the normal operation of the pump station. To optimize its inlet flow pattern, the size of the hollow rectification sill has been continuously improved through physical model tests to meet the requirements of the required pump station inlet flow field. In this paper, particle swarm optimization (PSO) was combined with the Gaussian process (GP) to establish a particle swarm-Gaussian process (PSO-GP) model to predict the velocity uniformity of the inlet sump of pump stations with different hole-to-height ratios, hole-to-width ratios, upper-to-lower sill length ratios, and sill height-to-water table ratios. Finally, the hollow rectification sill with the optimal size was obtained and tested in the physical model to compare the rectification effect with other sizes of hollow sills. The results show that the algorithm model can help the traditional physical experiment quickly predict the velocity uniformity of the inlet sump of the pump station. Through the optimization by the PSO-GP algorithm, we can get the optimal size of the hollow rectification sill. Its hole-to-height ratio is 0.62, its hole-to-width ratio is 0.37, upper-to-lower sill length ratio is 0.63, and sill height-to-water table ratio is 0.23. It shows that this method is practical in the optimization design of the hollow rectification sill and provides a new method for the optimization of the flow field in the forebay of the pump station.

Indocyanine green fluorescence imaging for evaluating blood flow in the reconstructed conduit after esophageal cancer surgery.

We investigated the effectiveness of indocyanine green (ICG) fluorescence blood flow imaging of the gastric conduit to evaluate anastomotic leakage after esophagectomy. We identified 19 articles using the PRISMA standard for systematic reviews. The more recent studies reported attempts at objective quantification of ICG fluorescence imaging, rather than qualitative assessment. Anastomotic leakage after esophagectomy occurred in 0-33% of the patients who underwent ICG fluorescence imaging. According to the six studies that compared the incidence of anastomotic leakage in the ICG group and the control group, it ranged from 0 to 18.3% in the ICG group and from 0 to 25.2% in the control group, respectively. Overall, the incidence of anastomotic leakage in the ICG group (8.4%) was lower than that in the control group (18.5%). Although the incidence of anastomotic leakage was as high as 43.1% in patients who did not undergo any intraoperative intervention for poor blood flow, it was only 24% in patients who underwent intraoperative intervention. This systematic review revealed that ICG fluorescence imaging may be a crucial adjunctive tool for reducing anastomotic leakage after esophagectomy, suggesting that it should be performed during esophageal reconstruction.

The Characteristics of Gas-Water Two-Phase Radial Flow in Clay-Silt Sediment and Effects on Hydrate Production

Many hydrate-bearing sediments in the Shenhu area of the South China Sea are featured with unconsolidated clayed silt, small particle size, and high content of clay, which can pose a great challenge for gas production. In order to investigate the gas-water relative permeability in clay-silt sediments, through a radial flow experiment, samples from the target sediment in the Shenhu area were selected and studied. The results show that the irreducible water saturation is high and the influence of the gas-water interaction is obvious. The relative permeability analysis shows that the two-phase flow zone is narrow and maximum gas relative permeability is below 0.1. The flow pattern in clay-silt sediment is more complicated, and the existing empirical models are inadequate for flow characterization. The depressurization method to extract a hydrate reservoir with clay-silt sediments faces the problem of insufficient production capacity. Compared with the ordinary hydrate reservoir with sandstone sediment, the hydrate reservoir with clay-silt sediment has a low permeability and poor gas flow capacity. The gas-water ratio abnormally decreases during the production. It is urgent to enhance production with cost-effective measures.

270 Evaluating Nutritional Strategies to Improve Performance of Poor Health Nursery Pigs

Abstract Nursery pigs are frequently faced with disease challenges and producers are seeking nutritional strategies to help pig performance and health. Therefore, our objective was to evaluate five dietary formulation strategies that may improve performance in poor health nursery flow pigs (confirmed Rotavirus A and hemolytic E. coli positive at d 14). A total of 431 weaned pigs (5.5 ± 1.25 kg BW) were assigned to pens (10–11 pigs/pen) and one of five diets (n = 8 pens/treatment) over a 63-day test period consisting of 4 diet phases using a complete randomized design. In phase 1 and 2, treatments were: 1) 15–25% low soybean meal (LSBM), 2) 35–45% high soybean meal (HSBM), 3) 130% increase in valine and isoleucine branched-chain amino acids (BCAA) to Lys, 4) 2.1% combination of C8, C10 and C12 medium chain fatty acids (MCFA), and 5) 20% modified oats (MO). All pigs were fed a common diet for phases 3 and 4. Within phase, all diets were isocaloric with similar SID Lys:ME. Pen was considered the experimental unit and data were analyzed with contrast statements comparing each diet against the LSBM control. Across all phases, compared to LSBM, HSBM, BCAA and MO did not alter ADG, ADFI and G:F (P &amp;gt; 0.10). However, MCFA reduced (P &amp;lt; 0.05) ADG in phase 1 (0.20 vs 0.16 kg) and 2 (0.45 vs 0.39 kg) and phase 2 ADFI (0.66 kg vs 0.58 kg) compared to the LSBM treatment. Overall (0–63 days), compared to the LSMB, the MCFA treatment reduced ADG (0.46 vs 0.42 kg, P = 0.004) and ADFI (0.75 vs 0.68 kg, P = 0.009). Diet did not affect mortality. These data report that MCFA attenuated nursery pig performance, while HSBM, MO and BCAA diets fed in phases 1 and 2 had no longitudinal impact on pig performance or health.

Correlating the cloud point of biodiesel with its fatty acid methyl ester composition: Multiple regression analyses and the weighted saturation factor (wSF)

Biodiesel is an alternative fuel that is typically composed of fatty acid methyl esters (FAME) from transesterification of fats or plant oils with methanol. When blended with conventional diesel fuels, biodiesel improves combustion quality and reduces harmful exhaust emissions. On the other hand, biodiesel has poor cold flow properties that can compromise its use during cold weather in moderate temperature climates. In the present study, nine mathematical models were proposed to calculate the cloud point (CP) of biodiesel based on the concentrations and melting properties of the FAME components. Experimental data were compiled for four biodiesel fuels made from canola, palm and soybean oils and yellow grease (CaME, PME, SME and YGME) plus 24 binary admixtures of these fuels. Four models were inferred from multiple regression analysis of CP as functions of Xi = (MPixi; MPi = melting point and xi = mole fraction of the FAME species). These models yielded high correlation coefficients (R2 ≥ 0.997) and low absolute average deviations (AAD) ≤ 0.60 K from analysis of calculated (CPcalc) versus measured data. The results helped to identify species that influenced the CP of FAME mixtures. Five additional models based on the weighted saturation factor (wSF) index as an independent variable for correlating the CP of biodiesel were inferred. The indices were calculated as weighted sums of Xi terms for species present in the FAME mixtures. Both an arbitrarily assigned weight factor (wi) and the MPi of the pure FAME species were used to calculate the wSF indices. The wSF index-based models were developed from regression analysis of FA profile and experimental CP data for the 28 FAME mixtures. Four models yielded R2 = 0.968–0.977 and AAD ≤ 0.73 from analysis of CPcalcversus measured CP data.

High frame rate optical flow estimation from event sensors via intensity estimation

Optical flow estimation forms the core of several computer vision tasks and its estimation requires accurate spatial and temporal gradient information. However, if there are fast-moving objects in the scene or if the camera moves rapidly, then the acquired images will suffer from motion blur, which will lead to poor optical flow estimation. Such challenging cases can be handled by event sensors which are a novel generation of sensors that acquire pixel-level brightness changes as binary events at a very high temporal resolution. Brightness constancy constraint, which is the basis of several optical flow algorithms cannot be directly used on event sensors making it challenging to estimate optical flow. We overcome this challenge by imposing brightness constancy constraint on intensity images predicted from event sensor data. For this task, we design a recurrent neural network that jointly predicts a sparse optical flow and intensity images from the event data. While intensity estimation is supervised using ground truth frames, optical flow estimation is self-supervised using the predicted intensity frames. However, in our case the temporal resolution of the ground truth intensity frames is far lower than the temporal resolution of the predicted intensity frames, making it challenging to supervise. As we use recurrent neural network, such a challenge can be overcome by sharing the weights for each of the predicted intensity frames. Quantitatively our predicted optical flow is better than previously proposed algorithms for optical flow estimation from event sensors. We also show our algorithm’s robustness against challenging cases of fast motion and high dynamic range scenes.