Introduction: Ambulatory blood pressure (BP) measurements using an arm-cuff can be both cumbersome and painful; limiting patients’ willingness to obtain routine measurements. A novel, simple, rapid, cuffless device (TouchBP™) calculates systolic and diastolic BP based on observed blood volume oscillations that result from the variable finger pressure on a custom sensor pad. The accuracy of this novel device relative to cuff based standards is not known. Methods: An independent physiology lab compared a blind TouchBP™ reading to reference SBP and DBP measurements made via an experienced auscultator. Subsequent data from 6 subjects was excluded due to signal artifacts resulting in 52 subjects in the analysis dataset. The Digitouch prediction algorithm was created using data from two previous clinical studies with different subject pools. Results: Among 52 subjects, SBP ranged from 95 to 167 mmHg, and DBP ranged from 58 to 106 mmHg. The SBP estimation error was 0.4 ± 7.9 mmHg, while DBP error was 0.3 ± 7.2 mmHg [bias ± precision]. (See Figure 1). The bias and precision results meet accuracy thresholds established by AAMI standard (bias< 5 mmHg and precision < 8mmHg). Conclusion: Digitouch’s TouchBP™, a novel cuffless mobile BP measurement system produces accuracy results like traditional oscillometric cuffs.