Chitosan-poly Vinyl Alcohol Research Articles

Integrated All-Fiber Electronic Skin toward Self-Powered Sensing Sports Systems.

The development of wearable electronic skins (E-skins) requires devices with high flexibility, breathability, and antibacterial activity, as in sports sensing technology. Here, we report a flexible, breathable, and antibacterial triboelectric nanogenerator (TENG)-based E-skin for self-powered sensing in volleyball reception statistics and analytics, which is fabricated by sandwiching a silver nanowire (Ag NW) electrode between a thermoplastic polyurethane (TPU) sensing layer and a poly(vinyl alcohol)/chitosan (PVA/CS) substrate. Benefiting from an outstanding breathability of 10.32 kg m-2 day-1 and biocidal properties of CS and Ag NW, the E-skin offers excellent thermal-moisture comfort and a remarkable antibacterial effect on Escherichia coli and Staphylococcus aureus. A pressure sensitivity of 0.3086 V kPa-1 is demonstrated in the sensing range of 6.65-19.21 kPa. Besides, a volleyball reception statistical and analytical system is further developed based on a 2 × 3 E-skin array. According to this work, the integration of wearable electronic devices with self-powered sensors may expand practical applications in sports.

Baicalin-liposomes loaded polyvinyl alcohol-chitosan electrospinning nanofibrous films: Characterization, antibacterial properties and preservation effects on mushrooms

To investigate antibacterial properties and application in food preservation of nanofibrous films (NFs), baicalin-liposomes (BCL-LPs) were loaded into polyvinyl alcohol-chitosan (PVA-CS) substrates to form NFs using electrospinning technology. The microstructure and phase identification of the NFs were characterized. The antibacterial properties and cytotoxicity of NFs were determined. The preservation of the NFs to mushrooms was evaluated. The results showed that smooth and uniform NFs were formed through molecular interaction between BCL-LPs and PVA-CS matrix. The NFs exhibited good antibacterial effects on Escherichia coli and Staphylococcus aureus due to the bacterial destruction resulting from the BCL delivery to bacterial cells by liposomes. In addition, the NFs were compatible with L929 fibroblasts. The BCL-LPs/PVA-CS NFs inhibited weight loss, browning, rancidity and bacterial growth as well as maintained the nutrients of mushrooms. The results show BCL-LPs/PVA-CS NFs possessed effective antibacterial properties, non-cytotoxicity and preservation performance, indicating the potential utilization as food-active packing.

Polyvinyl Alcohol/Chitosan and Polyvinyl Alcohol/Ag@MOF Bilayer Hydrogel for Tissue Engineering Applications.

In this paper, polyvinyl alcohol/Ag-Metal-organic framework (PVA/Ag@MOF) and polyvinyl alcohol/chitosan (PVA/CS) were used as the inner and outer layers to successfully prepare a bilayer composite hydrogel for tissue engineering scaffold. The performance of bilayer hydrogels was evaluated. The outer layer (PVA/CS) has a uniform pore size distribution, good water retention, biocompatibility and cell adhesion ability. The inner layer (PVA/Ag@MOF) has good antibacterial activity and poor biocompatibility. PVA, PVA/0.1%Ag@MOF, PVA/0.5%Ag@MOF, and PVA/1.0%Ag@MOF show anti-microbial activity in ascending order. However, its use as an inner layer avoids direct contact with cells and prevents infection. The cell viability of all samples was above 90%, indicating that the bilayer hydrogel was non-toxic to A549 cells. The bilayer hydrogel scaffold combines the advantages of the inner and outer layers. In summary, this new bilayer composite is an ideal lung scaffold for tissue engineering.

Sandwich nanohybrid of chitosan-polyvinyl alcohol for water treatment and Sofosbuvir drug delivery for anti-hepatitis C virus (HCV)

The incorporation between nano-polyvinyl alcohol (PVA) and nano-chitosan (Cs) to produce sandwich nanohybrid (SNH) for water treatment and improvement the adsorption of sofosbuvir drug (SOF). The photocatalytic activity and formation of reactive oxygen species (ROS) were detected with oxidation of organic dyes such as Rhodamine B (RhB), methylene blue (MB), and methyl orange (MO). The effect of SNH on the release of SOF in blood and inside the cells at pH 7.4 and pH 6.8, respectively were observed by UV–Visible spectroscopy (UV–Vis). The binding constant (Kb) was reported at 0.0035 min−1 and the loading constant at 0.0024 min−1, while the release efficiency was 42.6% at pH 7.4 and 74.7% at pH 6.8. The efficiency of photocatalytic activity against organic dyes MO, MB, and RhB are detected at 2.4% and 1%, and 42%, respectively. The cytotoxicity of SNH has been observed with MDA-MB-231 and HepG2 cell line with three concentrations of SNH, where the little concentration has low effect on the HepG2 and high viability, this result was reversed with the high concentration, also the yellow color due to the lysis of the cells. The antioxidant of the SNH was detected by FRAP technique.

Ethylenediamine-functionalized ZIF-8 for modification of chitosan-based membrane adsorbents: Batch adsorption and molecular dynamic simulation

In the current investigation, the incorporation of ethylenediamine (EDA)-modified ZIF-8 (zeolitic imidazolate framework) nanostructures into the chitosan/polyvinyl alcohol (CS/PVA) membrane adsorbents was explored for the elimination of reactive green 19 (RG) from aqueous solutions. Characterization of the synthesized EDA-modified ZIF-8 nanostructures and the membranes was carried out using XRD, SEM, BET and ATR-FTIR analyses. The CHN calculated the deacetylation degree of chitosan as 93%. To attain the maximum removal efficiency, three affecting operational parameters, including pH, adsorbent dosage, and initial concentration of dye, were optimized using the central composite design technique. The optimal conditions were resulted as; pH of 4, the adsorbent mass of 0.047 g, and the initial concentration of 70 mg L−1. Afterwards, the isothermal, kinetic, and thermodynamic studies were done under the optimal conditions attained. The outcomes displayed that the equilibrium and rate of reactive green 19 adsorption on the CS/PVA/EDA-modified ZIF-8 membrane surface obeyed the Freundlich isotherm and the pseudo-second order kinetic model, respectively. The adsorption capacity was found as 144.61 mg g−1. Furthermore, the entropy change (ΔS) and the enthalpy change (ΔH) for the adsorption were equal to 0.28 (kJ mol−1 K−1) and 4.83 (kJ mol−1), respectively. Negative values of ΔG° confirmed the spontaneity of the adsorption. Molecular dynamic simulation results showed that the interaction energies of CS/PVA/EDA-modified ZIF-8 membrane + RG system surpassed that of the CS/PVA + RG, which was in agreement with the adsorption performance results.

Preparation of polyvinyl alcohol–chitosan–NH4Br catalyst and its application to cycloaddition of carbon dioxide to propylene oxide

AbstractAn eco‐friendly polyvinyl alcohol (PVA)–chitosan(CS)–NH4Br catalyst was prepared using a modified solution method. Although the amounts of PVA and CS were fixed, the amount of NH4Br was varied in the range 15–45 wt.%. The catalytic performance of PVA–CS–NH4Br was compared based on the carbonation performance in the presence of single‐component catalysts (PVA, CS, and NH4Br) and dual component catalyst (PVA–CS). The catalytic activity of PVA–CS was inadequate and considerably less than that observed when either PVA or CS was exclusively loaded. The number of functional groups within the PVA–CS structure was presumed to have been reduced due to the interactions of the OH groups in PVA and CS. However, the PVA–CS–NH4Br catalyst distinctively exhibited its catalytic performance. It has been suggested that NH4Br aided in sustaining the innate functional groups that both PVA and CS have within the PVA–CS–NH4Br structure. These results indicate that the functional groups and nucleophiles within the PVA–CS–NH4Br structure more effectively participated in the carbonation of propylene oxide. Quantitatively, the addition of 30 wt.% NH4Br yielded the best performance. Characteristic analyses of the catalysts were performed using X‐ray diffraction, thermogravimetric analysis, Fourier transform infrared spectroscopy, and X‐ray photoelectron spectroscopy.

Fly ash modified magnetic chitosan-polyvinyl alcohol blend for reactive orange 16 dye removal: Adsorption parametric optimization

A magnetic biocomposite blend of chitosan-polyvinyl alcohol/fly ash (m-Cs-PVA/FA) was developed by adding fly ash (FA) microparticles into the polymeric matrix of magnetic chitosan-polyvinyl alcohol (m-Cs-PVA). The effectiveness of m-Cs-PVA/FA as an adsorbent to remove textile dye (reactive orange 16, RO16) from aquatic environment was evaluated. The optimum adsorption key parameters and their significant interactions were determined by Box-Behnken Design (BBD). The analysis of variance (ANOVA) indicates the significant interactions can be observed between m-Cs-PVA/FA dose with solution pH, and m-Cs-PVA/FA dose with working temperature. Considering these significant interactions, the highest removal of RO16 (%) was found 90.3% at m-Cs-PVA/FA dose (0.06 g), solution pH (4), working temperature (30 °C), and contact time (17.5 min). The results of adsorption kinetics revealed that the RO16 adsorption was better described by the pseudo-second-order model. The results of adsorption isotherm indicated a multilayer adsorption process as well described by Freundlich model with maximum adsorption capacity of 123.8 mg/g at 30 °C. An external magnetic field can be easily applied to recover the adsorbent (m-Cs-PVA/FA). The results supported that the synthesized m-Cs-PVA/FA presents itself as an effective and promising adsorbent for textile dye with preferable adsorption capacity and separation ability during and after the adsorption process.

Preparation and characterization of chitosan/polyvinyl porous alcohol aerogel microspheres with stable physicochemical properties

Chitosan/polyvinyl alcohol (CS/PVA) porous aerogel microspheres with stable physicochemical properties were obtained by gelation and freeze-drying process, and modified by adding different content of polyvinyl alcohol (PVA) into the microspheres. The physicochemical properties of porous aerogel microspheres, including porosity, swelling degree, acid-base resistance and compression performance were compared with chitosan (CS) microspheres. The microspheres were characterized by scanning electronic microscopy, Fourier transform infrared spectra, X-ray diffraction and compression test. The results showed that the structure of hybrid aerogel microspheres could be controlled by adjusting the content of PVA. The increase of PVA content reduced the pore size of CS/PVA porous aerogel microspheres, promoted the roughness of the surface and formed more orderly pore distribution. The higher PVA content was, the greater the swelling degree of the CS/PVA porous microspheres was. Adding proper amount of PVA into the CS/PVA microspheres could improve their acid resistance, but reduce their alkali resistance. Furthermore, the porosity of CS/PVA microspheres containing 33.3% PVA was the highest (78.3%) and the best compression strength (0.0505 MPa) when compression depth was 60% of the maximum height.

Preclinical assessment of chitosan–polyvinyl alcohol–graphene oxide nanocomposite scaffolds as a wound dressing

The present research aimed to examine the biological properties of chitosan (CS)–polyvinyl alcohol (PVA) scaffolds reinforced with graphene oxide (GO) nanosheets, as wound dressings. The scaffolds were characterized by various techniques. The scanning electron microscopy (SEM) and thermogravimetry analyses (TGAs) were used to investigate distribution of the GO within the polymer. The viscoelastic properties were evaluated by dynamic mechanical thermal analysis (DMTA) to examine the quality of a wound dressing. In vitro and in vivo studies were conducted to assess the biocompatibility of the scaffolds as wound dressing. The cell viability and proliferation results indicated that mouse fibroblast cells (L929) could adhere on the 50CS–50PVA/3 wt% GO scaffold. Herewith, the fabricated CS–PVA–GO nanocomposite scaffolds are suggested as promising biomaterials for skin tissue engineering and wound dressing.

Polyvinyl Alcohol/Chitosan Single-Layered and Polyvinyl Alcohol/Chitosan/Eudragit RL100 Multi-layered Electrospun Nanofibers as an Ocular Matrix for the Controlled Release of Ofloxacin: an In Vitro and In Vivo Evaluation

A novel nanofiber insert was prepared with a modified electrospinning method to enhance the ocular residence time of ofloxacin (OFX) and to provide a sustained release pattern by covering hydrophilic polymers, chitosan/polyvinyl alcohol (CS/PVA) nanofibers, with a hydrophobic polymer, Eudragit RL100 in layers, and by glutaraldehyde (GA) cross-linking of CS-PVA nanofibers for the treatment of infectious conjunctivitis. The morphology of the prepared nanofibers was studied using scanning electron microscopy (SEM). The average fiber diameter was found to be 123 ± 23 nm for the single electrospun nanofiber with no cross-linking (OFX-O). The single nanofibers, cross-linked for 10 h with GA (OFX-OG), had an average fiber diameter of 159 ± 30 nm. The amount of OFX released from the nanofibers was measured in vitro and in vivo using UV spectroscopy and microbial assay methods against Staphylococcus aureus, respectively. The antimicrobial efficiency of OFX formulated in cross-linked and non-cross-linked nanofibers was affirmed by observing the inhibition zones of Staphylococcus aureus and Escherichia coli. In vivo studies using the OFX nanofibrous inserts on a rabbit eye confirmed a sustained release pattern for up to 96 h. It was found that the cross-linking of the nanofibers by GA vapor could reduce the burst release of OFX from OFX-loaded CS/PVA in one layer and multi-layered nanofibers. In vivo results showed that the AUC0–96 for the nanofibers was 9–20-folds higher compared to the OFX solution. This study thus demonstrates the potential of the nanofiber technology is being utilized to sustained drug release in ocular drug delivery systems.

α-Relaxation and Temperature–Frequency Inelasticity of the Polyvinyl Alcohol–Chitosan Composite

α-Relaxation and Temperature–Frequency Inelasticity of the Polyvinyl Alcohol–Chitosan Composite

Radiation Modified CS/PVA Film with PVP Coating as Cu Adsorbent Material

Chitosan/Polyvinyl alcohol (CS/PVA) films were coated with layer of polyvinyl pyrrolidone (PVP) to improve its mechanical strength. In this study, chitosan/PVA mixture was first cast into film. The films were later dipped into different concentrations of PVP solutions at 1%, 3%, and 5%. They were then exposed to gamma (γ) radiation at 5,10,20 and 30 kGy. The tensile strength of chitosan/PVA films coated with 1% PVP was found to increase up to 31%. Elongation at break was improved by 1% PVP coating. The CS/PVA Removal Efficiency (RE) with or without PVP coatings were not affected by γ irradiation. Result shows that the best settings to enhance the tensile strength of CS/PVA films for Cu adsorption application was 1% PVP coating at 5 kGy γ radiation.

Controlled release of enrofloxacin by vanillin-crosslinked chitosan-polyvinyl alcohol blends

In transdermal drug delivery applications uniform drug distribution and sustained release are of great importance to decrease the side effects. In this direction in the present research, vanillin crosslinked chitosan (CS) and polyvinyl alcohol (PVA) blend based matrix-type transdermal system was prepared by casting and drying of aqueous solutions for local delivery of enrofloxacin (ENR) drug. Subsequently, the properties including the morphology, chemical structure, thermal behavior, tensile strength, crosslinking degree, weight uniformity, thickness, swelling and drug release of the CS-PVA blend films before and after crosslinking were characterized. In vitro drug release profiles showed the sustained release of ENR by the incorporation of vanillin as a crosslinker into the CS-PVA polymer matrix. Furthermore, the release kinetic profiles revealed that the followed mechanism for all samples was Higuchi and the increase of vanillin concentration in the blend films resulted in the change of diffusion mechanism from anomalous transport to Fickian diffusion. Overall, the obtained results suggest that the investigated vanillin crosslinked CS-PVA matrix-type films are potential candidates for transdermal drug delivery system.

Monitoring the infection process of Rhizopus stolonifer on strawberry fruit during storage using films based on chitosan/polyvinyl alcohol/polyvinylpyrrolidone and plant extracts

Different formulations based on nanoparticles of chitosan-plant extracts were evaluated to detect the infection process from the earliest stage of the fungus Rhizopus stolonifer on strawberry fruit during storage. Chitosan/polyvinyl alcohol (Ch/PVA) and chitosan/polyvinylpyrrolidone (Ch/PVP) films enriched with nanoparticles (NPs) of chitosan blended with plant extracts were prepared. They were placed inside a plastic package containing inoculated fruits and stored at 25 °C for 72 h. The thickness values of the films were in the range of 0.10 to 0.25 mm. All samples showed a maximum absorbance peak of about 300–320 nm; however, the Ch/PVP films enriched with NPs of chitosan and 10% of radish extract had an evident decrease in the optical absorbance as the fungal infection progressed. Additionally, as observed by scanning electron microscopy, the cross-section and surface morphology of films were not modified during storage, and the growth of R. stolonifer was evident after 48 h. Therefore, the Ch/PVP films enriched with chitosan NPs blended with 10% radish extract could be a reliable indicator of this fungus's growth.

Physico-Chemical Properties of a Hybrid Biomaterial (PVA/Chitosan) Reinforced with Conductive Fillers

In this study, a novel hybrid material based on Polyvinyl Alcohol-Chitosan (PVA-Chi) was made, reinforced with conductive fillers such as the polypyrrole (PPy), Poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT: PSS), carbon black (CB), and multi-wall carbon nanotube (MWCNT). In order to observe the mechanical and electrical responses of this composite material, for obtaining composite materials, and to characterize them for the development of applications in engineering, FTIR analysis made clear the different functional groups present in the matrix and the fillers used. Using quaternary mixtures (4 fillers) increased the contact angle, which increased hydrophobicity of the biocomposite. The Nyquist diagram of the analyzed samples showed a decrease in resistance and energy diffusion; the latter because of transferring electrons caused by the conductive polymers CB and the MWCNT. In the mechanical tension tests, Young’s modulus values of 18.386 MPa were obtained, in contrast with the material matrix of PVA-Chi, which showed values of 11.628 MPa. Morphological analysis by SEM showed the materials got were homogeneous. The materials got showed higher electrical conductivity in the OH’s presence and NH2 groups, which could have possible applications in biopolymer electrodes.

Chitosan/PVA silver nanocomposite for butachlor removal: Fabrication, characterization, adsorption mechanism and isotherms

Silver nanoparticle (AgNP) incorporated chitosan-Polyvinyl alcohol (Ch/PVA) hydrogel nanocomposite was fabricated by repeated freeze-thaw treatment using glutaraldehyde as crosslinker for removal of herbicide butachlor from aqueous solution. Ch/PVA hydrogel provided a matrix for in-situ immobilization of AgNPs and were characterized by various physicochemical techniques. AgNPs of size 5−20 nm possessed crystalline structure, led to increase in thermal stability and surface area after incorporation into Ch/PVA hydrogel. Ch/PVA hydrogel nanocomposite showed maximum adsorption of butachlor (86.55 %) at 30 °C and pH 3.0, while Ch/PVA-Ag showed a slight increase in adsorption of butachlor following pseudo-second order kinetics. Langmuir and Freundlich models with different error functions (R2, R2adj, RSME, χ2 and RSS), confirmed monolayer adsorption of butachlor.

Preparation and evaluation of chitosan-polyvinyl alcohol/polyhexamethylene guanidine hydrochloride antibacterial dressing to accelerate wound healing for infectious skin repair.

BackgroundWound infections, especially multidrug-resistant (MDR) bacterial infections, are a major challenge in clinical medicine.MethodsIn this study, a new type of antibacterial sponge was prepared from a solution containing a chitosan-polyvinyl alcohol (CTS-PVA) emulsion with added polyhexamethylene guanidine hydrochloride (PHMG) in a homogeneous medium using lyophilization technology. The antibacterial ability of and CTS-PVA/PHMG sponge against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Candida albicans, Methicillin-resistant Staphylococcus aureus, multidrug-resistant Pseudomonas aeruginosa, and multidrug-resistant Acinetobacter baumannii in vitro. The structure and physical properties were characterized. The sponge dressing was tested in a Pseudomonas aeruginosa-infected full-thickness mouse skin wound defect model. The effects were evaluated by wound area measurement and histological analysis.ResultsThe CTS-PVA/PHMG sponge showed broad-spectrum antibacterial ability, including for MDR bacterial stains from clinical sources, while maintaining excellent physicochemical properties, including a high swelling degree and good moisture retention capability. Scanning electron microscopy images displayed the surface morphology of the CTS-PVA/PHMG sponge dressing. The detection of the wound healing rate and histological analysis supported that the new dressing can alleviate the inflammation and accelerate the healing speed of infected wounds and in vivo.ConclusionsCTS-PVA/PHMG sponge shows broad-spectrum antibacterial activity, which can provide a new pathway for clinical prevention and treatment of superbug-infected wounds.

Enhancing anammox resistance to low operating temperatures with the use of PVA gel beads

Low temperatures, or a sudden decrease in operating temperature, can seriously inhibit anammox activity, it is, therefore, important to maintain anammox activities at a low temperature. In this study, the use of gel beads to enhance the resistance of anammox biomass to a low temperature was investigated. The performance of three reactors: R1 without gel beads; R2 with polyvinyl alcohol/chitosan (PVA/CS); R3 with PVA/CS/Fe, was studied and compared in a temperature transition from 35 to 8 °C. When the operating temperature was ≥25 °C, there was little difference in nitrogen removal among the three reactors. Decreasing the temperature to < 25 °C created obvious difference between R1 and R2/R3. R1 had a nitrogen removal efficiency (NRE) of 33.1 ± 25.3% at 10 °C, significantly lower than that of R2 (90.5 ± 2.5%) or R3 (87.7 ± 11.1%). Unclassified Candidatus Brocadiaceae was the dominant genus at 10 °C, with an abundance of 44.4, 56.5 and 58.7% in R1, R2 and R3, respectively. These differences were attributed to the use of gel beads, which promoted the granulation of both the non-immobilized sludge and the immobilized biomass, resulting in higher anammox activities in R2/R3. The non-immobilized sludge of R1 was dominated by small particles (<300 μm) at 10 °C, while in R2 and R3 large particles (1000–2000 μm) were the main components. Furthermore, the immobilized biomass on gel beads exhibited much higher anammox activity and maintained a relatively high level of nitrate reductase and nitrite reductase in response to the temperature decrease. The Fe2+/Fe3+ in the PVA/CS/Fe gel beads further promoted microbial aggregation and led to an improved performance in R3 compared to R2. The results of this study demonstrate an effective approach to increase anammox resistance at low operating temperatures.

Insight: High intensity and activity carrier granular sludge cultured using polyvinyl alcohol/chitosan and polyvinyl alcohol/chitosan/iron gel beads

The newly developed carrier granular sludge (CGS) with polyvinyl alcohol/chitosan (PVA/CS) and PVA/CS/Fe gel beads assistance showed higher intensity and anammox activity than the natural granular sludge (NGS). Through comprehensive investigation, it was found: (1) the gel beads provided a stable framework of cells entangle with extracellular polymeric substances (EPS) to enhance the sludge intensity. In this framework, β-polysaccharides are distributed at the edge of CGS as a protection layer, α-polysaccharides and proteins are spread in the whole cross-section as backbones, and Fe2+/Fe3+ in CGS-PVA/CS/Fe act as bridges to link with the negatively charged groups on bacterial surfaces and proteins. (2) The porous gel beads satisfied a relatively unimpeded mass transfer. Thus, the sludge activity, microbe’s metabolism, membrane transportation and environmental adaption in CGS were apparently improved. The results improved the understanding about the advantages of the CGS and indicated their possible application in full-scale anammox processes.

Fabrication and Characterization of Multiple Herbal Extracts-loaded Nanofibrous Patches for Topical Treatment of Acne Vulgaris

Herbal extracts have recently received considerable interest in acne therapy owing to their enhanced skin compatibility compared with antibiotics and synthetic agents. In this study, electrospun poly (vinyl alcohol)/chitosan (PVA/CS) fibrous patch incorporating a combination of herbal extracts with complementary mechanisms of action was developed as an alternative acne therapy for patients with resistance to the conventional treatments. The herbal extracts-loaded electrospun fibers displayed uniform and smooth-surfaced nanofibers (dia. 100–300 nm), high drug loading efficiency (89.5–97.7 %) and good water absorbing properties. Results of the in vitro release and antibacterial studies suggest the patches are capable of sustained release of polyphenol-rich extracts, which may, together with the chitosan present in the fiber, endow the patch with potent bacterial inhibition of Propionibacterium acnes. The herbal extracts-loaded patches exhibited pronounced clinical therapeutic efficacy in treating mild-to-moderate facial acne by rapidly reducing inflamed lesions and restoring epidermal barrier. Also, the herbal patches demonstrated improved biocompatibility or tolerability in comparison with the synthetic drug benzoyl peroxide. Overall, the present study has provided a facile approach to develop biocompatible polymers based electrospun fibrous patch for the efficient delivery of herbal extracts for topical skin therapy, opening new perspectives for a new generation of cosmetotextiles.