Breast cancer (BC) most diagnosed invasive disorder and important cause of casualty for women worldwide. Indian contest BC most commonly spread disease among females. This problem is more alarming to economically developing country like India. Government of India made a lot of effort to make aware the women of the country, but despite of availability of diagnostic tool, prediction of disease in real situation is still a puzzle for researchers. Timely detection and categorization of BC using the evolving techniques like Machine Learning (ML) can show a significant role in BC identification and this could be a preventive policy which effectively reduces the risk of BC patients. Although there are four Kernels in ML, are widely in use but their performance varies with the kind of data available. In this study we, apply four different Kernels such as Linear Kernel (LK), Polynomial Kernel (PK), Sigmoid Kernel (SK) and Radial Basis Function Kernel (RBFK) on BC dataset. We estimated the performance of Support Vector Machine Kernels (SVM-K) on BC dataset .The basic idea is to check the exactness of SVM-K to classify WBCD in terms of effectiveness with respect to accuracy, runtime, specificity and precision. The investigations outcome displays that RBFK provides greater accuracy with minimal errors