The lithic units of polymict breccia 14321 (Big Bertha) have been grouped according to composition, texture, degree of metamorphism, and additional criteria based on a systematic study of the interrelationships of all clast-matrix pairs. From this information it has been possible to reconstruct the assembly and metamorphic history of this breccia. The earliest formed fragmental component of 14321 (microbreccia-1) is dominated by KREEP-rich norite, extruded and subsequently brecciated and lithified in an ejecta blanket at approximately 1000°C in the general region of Mare Imbrium after the Serenitatis impact but prior to the Imbrium impact. This early microbreccia component and lesser amounts of mare-type basalt, microgranite, rhyolite glass, anorthosite and olivine microbreccia were assembled at the Apollo 14 site as part of the Fra Mauro ejecta blanket from the Imbrium impact. The resulting microbreccia-3 incorporates all the lithic types above and accretionary lapilli structures (microbreccia-2) in a dark matrix annealed at approximately 700°C. A later impact on the Fra Mauro excavated and mutually abraded microbreccia-3 and a local, 14321-type, basalt which were assembled into polymict breccia 14321. Final placement of 14321 at its sampling location was accomplished during the minor Cone Crater impact event.