Five square reinforced concrete (RC) stub columns were fabricated and experimental tested under an axial compression load in order to study the effectiveness of strengthening by using prestressed carbon fiber reinforced polymer (CFRP) strips. The specimens tested included one un-strengthened and four strengthened. Three specimens were strengthened by using prestressed strips, and the other one strengthened by using non-prestressed was used to compare. The prestress of the strip was achieved by tensed using a special device before it was pasted to the column. The experimental data such as the failure modes, load-displacement curves and strain distribution of CFRP strips were obtained. The effects of prestress magnitude of CFRP strips on the ultimate bearing capacity and deformation capacity of the specimens were analyzed. The results show that the prestress of CFRP strips can effectively increase the ultimate capacity and delay the crack occurrence of the specimens. And ultimate strain, plastic deformation of the specimens were also improved with increase of prestress magnitude of strip.