The mono- and bimetallic catalytic polymeric hollow-fiber reactors were established with catalytic polymeric cellulose acetate (CA) hollow fibers prepared by supporting the polymer-anchored mono- or bimetallic catalyst in/on the inner wall of the hollow fibers. The selective hydrogenation of cyclopentadiene to cyclopentene was efficiently carried out in the above catalytic polymeric hollow-fiber reactors, especially in the NaBH 4 reduced bimetallic PVP–Pd–0.5Co/CA hollow-fiber reactor under mild conditions of 40°C and 0.1 MPa. It was found that there was a remarkable synergic effect of palladium and cobalt reduced by NaBH 4 in the bimetallic PVP–Pd–0.5Co/CA hollow-fiber reactor, which results in a 97.5% conversion of cyclopentadiene and a 98.4% selectivity for cyclopentene.