AbstractExcellent in vivo thromboresistance has been obtained for FEP Teflon and for a polyether urethane prepared with electronegative surfaces using the electret effect. In vitro tissue culture studies have shown a marked improvement in tissue compatibility for negatively electrified Teflon. Studies on other materials, including Hypalon rubber, sulfonate cross‐linked Hypalon and Kel F have shown a moderate improvement in blood compatibility. These in vitro and in vivo experiments will be described. Surface physical properties of these electrified materials, including water contact angle and charge, have been measured. Correlations between surface physical measurements and blood compatibility data will be presented.