This research study an experimental and optimization work of the effect of moisture on the shear strength of adhesive joints and improvement by adding variable concentration of PVA to PVP. In this work, shear strength samples from Cu-Cu and the adhesive made from dissolving 16 grams of polyvinyl pyrrolidone (k30) and 8 grams of polyvinyle Alcohol in 50 ml of water was studied. This study condensed on the effect of variable under pressure of a fixed rate of 5 MPa. For temperatures (225) °C with times (10) minutes under the same. It was noticed that the best resulted found at a temperature of 225 °C and time of 10 minutes and 50% from PVA and 50% PVP the best result of shear strength, reaching overhead hanging to 1240 N and 920 at 265 °C that there is decreasing in the resistance of the adhesive with the emerging time (0,2, 4, 6, 7, 9) at room temperature, and using a Neural network to prediction the results.