Reviewed by: Cold War Resistance: The International Struggle Over Antibiotics by Marc Landas Christoph Gradmann Marc Landas. Cold War Resistance: The International Struggle Over Antibiotics. Lincoln: Potomac Books/University of Nebraska Press, 2020. viii + 359 pp. $39.95 (978-1-64012-105-8). The history of antibiotics can look back at a long and mostly venerable tradition of attracting expert historians, practitioners, journalists, and very often combinations of any of these. Bernard Dixon’s landmark popular science paper “Antibiotics on the Farm” from 1967 popularized contemporary work on horizontal gene transfer, which revolutionized the understanding of antibiotic resistance.1 Stuart Levy’s “The Antibiotic Paradox” of 1992 paved the way to the insight that antibiotics modernized the problem of bacterial infection rather than solving it.2 Beginning perhaps with Robert Bud’s “Penicillin: Triumph and Tragedy” from 2007, authors such as Claas Kirchhelle, Scott Podolsky, and Maria Santesmases have given us rich histories of antibiotics.3 At the same time, inspiring journalistic accounts continue to appear; Maryn McKenna’s “Big Chicken” of 2017 being a recent example of rock-solid and inspiring journalistic writing.4 Marc Landas’ Cold War Resistance falls into the group of more journalistic accounts. On some three hundred pages and through fifteen chapters it attempts to draw a line from Cold War politics to the emergence of antibiotic resistance. Drawing on many interesting sources, most of them published, the author goes through an enormous panorama of subjects: antibiotic drug development during World War II, the rise of the American pharmaceutical industry, Germany’s failure to participate in the invention of first generation antibiotics, Soviet science and industry under Lysenko (and Stalin), the repeated failure of phage therapy, the after-war food industry and the career of antibiotics as growth promoters, resistant staphylococcus in hospitals, and biological weapons. In addition, numerous small stories from any country that ever produced or used antibiotics are woven into the text. It is Landas’ main contention that the politicization of antibiotic drugs during the Cold War accelerated the development of antibiotic resistance. And while it is certainly correct that politics was influential in antibiotics history, starting from the drugs being a part of the allied war effort, this hypothesis is nowhere fully [End Page 280] spelled out and discussed with all its implications. The laudable aim to deliver a contextual history of antibiotic resistance results in sometimes dissociated histories where a colorful description of the battle of Stalingrad somehow leads to discussing the war-time production of antibiotics or the lack of in the Soviet Union. In a similar vein, discussion of the atomic bomb wanders through a chapter, but it is mostly left to the reader to guess what purpose this serves in the text. What does not help either is that chapters are simply numbered rather than having titles and so diverse in their content that a reader would struggle to say what each of them is about. Also, it needs to be said that the book, while mobilizing interesting published sources, is not entirely up-to-date when it comes to relevant secondary sources. As a result, the pages about Germany’s wartime effort and its accent on sulphonamides rather than antibiotics is shot through with small mistakes, all of which could have been avoided had John Lesch’s work on the issue been consulted.5 For the passages on resistant staphylococcus, insight from Kathryn Hillier’s work is missing.6 Other context is perhaps overrated. One can share the author’s fascination with Lysenkoism, but it remains an open question if the shortcomings of the Soviet pharmaceutical industry can be reduced to the idiosyncrasies of a neo-Lamarckian ideologue. The question that should have been explored systematically is how important the stated connection of antibiotic resistance and the Cold War was. If the growth of antibiotic resistance was advanced by Cold War politics, then why did it not ease or even stall after that? If we look at recent reports on antibiotic resistance in global health, it does in fact appear to be the case that the problem escalated after the Cold War ended, from the 1990s. It was then that global antibiotic production went to India...