Abstract American federalism in 2022–2023 saw a continued escalation of the culture wars, with persistent battles fought between the heavily polarized political parties, different levels of government (including federal versus state governments and state versus local governments), and between states and private business. Policy conflicts have centered on a variety of issues related to reproductive rights, K-12 education, and gun policy, among others. This overview of American federalism during the last year proceeds by first considering major policy activity in Congress, much of which holds significant implications for federalism. Next, we discuss the 2022 midterm elections and the dynamics that largely prevented what many expected to be a “red wave”. We then move to discuss significant policy shifts in the areas of civil rights and liberties, environmental policy, and labor, with an emphasis on state policymaking and court decisions. A central theme has been the intensification of cultural disputes as a policymaking focus, particularly at the state level.