Polar Carboxyl Research Articles

Data-Driven Approach for Designing Eco-Friendly Heterocyclic Compounds for the Soil Microbiome.

Soil microbiota plays crucial roles in maintaining the health, productivity, and nutrient cycling of terrestrial ecosystems. The persistence and prevalence of heterocyclic compounds in soil pose significant risks to soil health. However, understanding the links between heterocyclic compounds and microbial responses remains challenging due to the complexity of microbial communities and their various chemical structures. This study developed a machine-learning approach that integrates the properties of chemical structures with the diversity of soil bacteria and functions to predict the impact of heterocyclic compounds on the microbial community and improve the design of eco-friendly heterocyclic compounds. We screened the key chemical structures of heterocyclic compounds─particularly those with topological polar surface areas (<74.2 Å2 or 111.3-154.1 Å2), carboxyl groups, and dissociation constant, which maintained high soil bacterial diversity and functions, revealing threshold effects where specific structural parameters dictated microbial responses. These eco-friendly compounds stabilize communities and increase beneficial carbon and nitrogen cycle functions. By applying these design parameters, we quantitatively assessed the eco-friendliness scores of 811 heterocyclic compounds, providing a robust foundation for guiding future applications. Our study disentangles the critical chemical structure-related properties that influence the soil microbial community and establishes a computational framework for designing eco-friendly compounds with ecological benefits from an ecological perspective.

Screening and isolation of polyethylene microplastic degrading bacteria from mangrove sediments in southern China.

Mangrove sediments in southern China are a large reservoir for microplastics (MPs). In particular, polyethylene microplastics (PE-MPs) are environmentally toxic and have accumulated in large quantities in these sediments, posing a potential threat to the overall mangrove and the organisms that inhabit it. We screened sediments from 5mangrove sites and identified a potential source of PE-MP degrading bacteria. We purified the bacterial strains Acinetobacter venetianus E1-1, Serratia marcescens E1-2, Chryseobacterium cucumeris E1-3 and Bacillus albus E1-4 from P1 that were able to reduce the mass of the 75μm PE-MPs substrate by 3.67 to 6.59%, respectively and use it as a sole carbon source. The degradation was accompanied by surface deformation of the MPs and introduction of polar oxygen-containing carbonyl and carboxylic acid functional groups thereby decreasing the hydrophobicity of the substrate. Whole-genome sequencing of S. marcescens E1-2, the most effective degrader, revealed it possesses a variety of enzymes and metabolic pathways related to PE degradation. Our results indicated that the PE-MP degrading bacteria isolated from screened mangrove sediments represent an effective strategy for in situ MP pollution remediation and uncovering mechanisms associated with PE degradation.

Zn2+ flux regulator to modulate the interface chemistry toward highly reversible Zn anode

The persistent challenges of diminished coulombic efficiency (CE) and the formation of Zn dendrites at the Zn anode interface substantially hinder the cycle life of aqueous Zn-ion batteries (AZIBs), thereby impeding their widespread deployment. To address these issues, multifunctional 2-amino-5-guanidino-pentanoic acid (AGPA) additive is introduced into the electrolyte, as a novel Zn2+ flux regulator (ZFR) to improve the reversibility and durability of Zn anodes. The distinctive zincophilicity of amino groups empowers such ZFR with a higher adsorption energy, enabling the construction of a multifunctional molecular adsorption layer on Zn electrode surface. Simultaneously, leveraging the exceptional nucleophilic characteristics of polar carboxyl groups, AGPA molecules tend to form chelating bonds with Zn2+ for manipulating the interface chemistry and solvation chemistry. The functional groups in ZFR work in synergy to attract zinc ions for homogenizing Zn2+ flux and suppress the interfacial side reactions, resulting in uniform dendrite-free Zn deposition. Consequently, the Zn//Zn symmetrical cell achieves an extended cycle life of 5500 h. Moreover, the ZFR enables stable operation of the full batteries with an ultra-long cycling lifespan of 6000 cycles at 5 A/g, showcasing the effectiveness of ZFR in advancing the commercialization of AZIBs.

Polymerizable fatty acid surfactant: Encapsulation of organic pigments for excellent colloidal stability in aqueous solution and water-repellent property

Organic pigments are indispensable in various applications due to their vibrant colors and durability, yet their low polarity often hinders their dispersion in an aqueous solution, leading to large aggregation and sedimentation. To address these limitations, dispersants and encapsulation techniques have been explored. In this study, nanoscale encapsulated pigments were synthesized using a novel polymerizable surfactant, sodium 11-methacrylamidoundecanoic acid (NaMAAUA), along with hydrophobic monomer of styrene or butyl methacrylate. NaMAAUA contains a pendant group of amphiphilic fatty acid, and acts as a dispersant and emulsifier, forming a copolymer shell around the pigments. The apolar tail in NaMAAUA provides hydrophobic interaction with pigments, and the polar carboxyl headgroup exposes in the water phase and enables the formation of strong hydrogen bonds with cellulose. Therefore, the resulting encapsulated pigment exhibits excellent dispersion stability, water-repellent property, washing fastness and UV resistance when applied to paper and cotton fabric, expanding the practical utility of organic pigments in an environmentally conscious manner. Characterization via various analytical techniques validates the efficacy of this approach, paving the way for enhanced pigment applications.

Designing multifunctional, 3D cross-linked network binder for actual use in high performance lithium ion batteries silicon based anodes

Binders have been proved to be an economical and effective approach for accelerating the industrial application of silicon based anodes. Herein, a 3D network binder (H-PAN-g-ECH) with multifunctional groups, is constructed by crosslinking polyacrylonitrile (PAN) hydrolysate (H-PAN) with epichlorohydrin (ECH). Strong polar groups carboxylate (-COO-) and amide (-CONH2) obtained from hydrolysis of PAN as well as the original cyanide (-CN) enhance the adhesive ability of H-PAN-g-ECH to not only active material but also current collector, and thus sustain the structure integrity of the electrode. In addition, the network structure proposed by linking H-PAN with short-chain molecules endows H-PAN-g-ECH with facilitated Li-ion transmission and improved mechanical property to accommodate the great volume variation of Si during cycling. The as-prepared H-PAN-g-ECH possesses multiple interfacial adhesion and robust mechanical performance, which improves the electrochemical property of silicon anode with high areal capacity. In combination with good processability, H-PAN-g-ECH is verified to be a superior binder in use of practical Si based anodes.

Ionic Selective Separator Design Enables Long‐Life Zinc–Iodine Batteries via Synergistic Anode Stabilization and Polyiodide Shuttle Suppression

AbstractAqueous zinc–iodine batteries show immense potential in the electrochemical energy storage field due to their intrinsic safety and cost‐effectiveness. However, the rampant dendritic growth and continuous side reactions on the zinc anode, coupled with the shuttling phenomenon of polyiodides, severely affect their cyclic life. In response, this study utilizes a carboxyl‐functionalized metal‐organic framework UiO‐66‐(COOH)2 (UC) to modify commercial glass fiber (GF) to develop a novel ionic selective separator (UC/GF). This separator exhibits cation exchange ability for Zn2+ and polyiodides, thereby simultaneously stabilizing the zinc anode and inhibiting the shuttle effect of polyiodides. Enhanced by the abundant polar carboxyl groups, the UC/GF separator can effectively facilitate Zn2+ ion transport and accelerate the desolvation of hydrated zinc ions by its zincophilicity and hydrophilicity, while significantly hindering the transfer of polyiodides via electrostatic repulsion. Consequently, the Zn|UC/GF|Zn symmetric battery enables a long lifespan of over 3400 h at a current density of 5.0 mA cm−2, while the Zn|UC/GF|I2 exhibits an exceptional discharge capacity of 103.8 mAh g−1 after 35 000 cycles at 10 C with a capacity decay rate of only 0.0013% per cycle. This separator modification strategy that synergistically optimizes anode and cathode performance provides unique insights into the commercialization of zinc–iodine batteries.

Unimolecular Chemiexcited Oxygenation of Pathogenic Amyloids

AbstractPathogenic protein aggregates, called amyloids, are etiologically relevant to various diseases, including neurodegenerative Alzheimer disease. Catalytic photooxygenation of amyloids, such as amyloid‐β (Aβ), reduces their toxicity; however, the requirement for light irradiation may limit its utility in large animals, including humans, due to the low tissue permeability of light. Here, we report that Cypridina luciferin analogs, dmCLA‐Cl and dmCLA‐Br, promoted selective oxygenation of amyloids through chemiexcitation without external light irradiation. Further structural optimization of dmCLA‐Cl led to the identification of a derivative with a polar carboxylate functional group and low cellular toxicity: dmCLA‐Cl‐acid. dmCLA‐Cl‐acid promoted oxygenation of Aβ amyloid and reduced its cellular toxicity without photoirradiation. The chemiexcited oxygenation developed in this study may be an effective approach to neutralizing the toxicity of amyloids, which can accumulate deep inside the body, and treating amyloidosis.

Unimolecular Chemiexcited Oxygenation of Pathogenic Amyloids.

Pathogenic protein aggregates, called amyloids, are etiologically relevant to various diseases, including neurodegenerative Alzheimer disease. Catalytic photooxygenation of amyloids, such as amyloid-β (Aβ), reduces their toxicity; however, the requirement for light irradiation may limit its utility in large animals, including humans, due to the low tissue permeability of light. Here, we report that Cypridina luciferin analogs, dmCLA-Cl and dmCLA-Br, promoted selective oxygenation of amyloids through chemiexcitation without external light irradiation. Further structural optimization of dmCLA-Cl led to the identification of a derivative with a polar carboxylate functional group and low cellular toxicity: dmCLA-Cl-acid. dmCLA-Cl-acid promoted oxygenation of Aβ amyloid and reduced its cellular toxicity without photoirradiation. The chemiexcited oxygenation developed in this study may be an effective approach to neutralizing the toxicity of amyloids, which can accumulate deep inside the body, and treating amyloidosis.

Low-Temperature Deposited Amorphous Poly(aryl ether ketone) Hierarchically Porous Scaffolds with Strontium-Doped Mineralized Coating for Bone Defect Repair.

In recent years, the demand for clinical bone grafting has increased. As a new solution for orthopedic implants, polyether ether ketone (PEEK, crystalline PAEK) has excellent comprehensive performance and is practically applied in the clinic. In this research, a noteworthy elevated scheme to enhance the performance of PEEK scaffolds is presented. The amorphous aggregated poly (aryl ether ketone) (PAEK) resin is prepared as the matrix material, which maintains high mechanical strength and can be processed through the solution. So, the tissue engineering scaffolds with multilevel pores can be printed by low-temperature deposited manufacturing (LDM) to improve biologically inert scaffolds with smooth surfaces. Also, the feature of PAEK's solution processing is profitable to uniformly add the functional components for bone repair. Ultimately, A system of orthopedic implantable PAEK material based on intermolecular interactions, surface topology, and surface modification is established. The specific steps include synthesizing PAEK that contain polar carboxyl structures, preparing bioinks and fabricating scaffolds by LDM, preparation of scaffolds with strontium-doped mineralized coatings, evaluation of their osteogenic properties in vitro and in vivo, and investigation on the effect and mechanism of scaffolds in promoting osteogenic differentiation. This work provides an upgraded system of PAEK implantable materials for clinical application.

Stable anode/separator interface enabled by graft modification of polypropylene separator via electron beam irradiation technique toward high-performance sodium metal batteries

Sodium metal batteries (SMBs) are considered as strong alternatives to lithium-ion batteries (LIBs), due to the inherent merits of sodium metal anodes (SMAs) including low redox potential (−2.71 V vs. SHE), high theoretical capacity (1166 mAh g−1), and abundant resources. However, the uncontrollable Na dendrite growth has significantly impeded the practical deployment of SMBs. Separator modification has emerged as an effective strategy for substantially enhancing the performance of SMAs. Herein, for the first time, we present the successful grafting polyacrylic acid (PAA) onto polypropylene (PP) separators (denoted as PP-g-PAA) using highly efficient electron beam (EB) irradiation to improve the cyclability of SMAs. The polar carboxyl groups of PAA can facilitate the electrolyte wetting and provide ample mechanical strength to resist dendrite penetration. Consequently, the regulation of Na+ ion flux enables uniform Na+ deposition with dendrite-free morphology, facilitated by the favorable anode/separator interface. The PP-g-PAA separator significantly enhances the cyclability of fabricated cells. Notably, the lifespan of Na||Na symmetric cells can be extended up to 5519 h at 1 mA cm−2 and 1 mAh cm−2. The stable design of the anode/separator interface achieved through polyolefin separator modification presented in this study holds promise for the further advancement of next-generation advanced battery systems.

Achieving Dendrite-Free Zinc Metal Anodes via Molecule Anchoring and lon-Transport pumping.

The potential for scale-up application has been acknowledged by researchers for rechargeable aqueous zinc-ion batteries (ZIBs). Nonetheless, the progress of the development is significantly impeded due to the instability of the interface between the zinc anode and electrolyte. Herein, efficient and environmentally benign valine (Val) were introduced as aqueous electrolyte additive to stabilize the electrode/electrolyte interface (EEI) via functional groups in additive molecules, thus achieving reversible dendrite-free zinc anode. The amino groups present in Val molecules have a strong ability to adsorb on the surface of zinc metal, enabling the construction of anchored molecular layer on the surface of zinc anodes. The strongly polar carboxyl groups in Val molecules can act as ion-transport pumps to capture zinc ions in the electric double layer (EDL) through coordination chemistry. Therefore, this reconstructed EEI could modulate the zinc ion flux and simultaneously suppress side reactions and dendritic growth of Zn. Consequently, a long stable cycling up to 1400 h at a high current density of 20 mA cm-2 is achieved. Additionally, Zn//V2O5 full cell with Val additive exhibit enhanced cyclability, retaining 77 % capacity after 3000 cycles, displaying significant potential in promoting the commercialization of ZIBs.

Constructing high-toughness polyimide binder with robust polarity and ion-conductive mechanisms ensuring long-term operational stability of silicon-based anodes

Silicon-based materials have demonstrated remarkable potential in high-energy–density batteries owing to their high theoretical capacity. However, the significant volume expansion of silicon seriously hinders its utilization as a lithium-ion anode. Herein, a functionalized high-toughness polyimide (PDMI) is synthesized by copolymerizing the 4,4′-Oxydiphthalic anhydride (ODPA) with 4,4′-oxydianiline (ODA), 2,3-diaminobenzoic acid (DABA), and 1,3-bis(3-aminopropyl)-tetramethyl disiloxane (DMS). The combination of rigid benzene rings and flexible oxygen groups (-O-) in the PDMI molecular chain via a rigidness/softness coupling mechanism contributes to high toughness. The plentiful polar carboxyl (–COOH) groups establish robust bonding strength. Rapid ionic transport is achieved by incorporating the flexible siloxane segment (Si-O-Si), which imparts high molecular chain motility and augments free volume holes to facilitate lithium-ion transport (9.8 × 10−10 cm2 s−1 vs. 16 × 10−10 cm2 s−1). As expected, the SiOx@PDMI-1.5 electrode delivers brilliant long-term cycle performance with a remarkable capacity retention of 85% over 500 cycles at 1.3 A g−1. The well-designed functionalized polyimide also significantly enhances the electrochemical properties of Si nanoparticles electrode. Meanwhile, the assembled SiOx@PDMI-1.5/NCM811 full cell delivers a high retention of 80% after 100 cycles. The perspective of the binder design strategy based on polyimide modification delivers a novel path toward high-capacity electrodes for high-energy–density batteries.

Original Synthesis of Ethylene‐Acrylic Acid (ester) Copolymers Derivatives from 5‐substituted Cyclooctenes with A Controllable Way Via Ring‐Opening Metathesis Polymerization

AbstractHigh‐value grades of ethylene‐acrylic acid (EAA) and ethylene‐acrylic ester copolymers have been producing produced from ethylene, acrylic acid (AA), and the alcohol derivative via radical reaction in autoclave reactor at a temperature of 150‒230 °C and pressure of 150–300 MPa. In this paper, EAA and its ester derivatives are originally created from the 5‐substituted cyclooctenes (COE) with side chains of carboxylic acid or ester derivatives by ring‐opening metathesis polymerization (ROMP) at normal temperature and pressure. Especially, the controllable insertion of side chain is effectively achieved by altering the molar ratio of COE and 5‐substituted COE. Furthermore, the polar carboxyl groups (ester groups) have a detrimental effect on the order assigns of the linear backbone and thus hindered crystallization, indicating relatively lower crystallizing and melting temperature with an increase in the content of side chain. As the amounts of polar groups raised, the stiffness of chain segments enhanced, thereby leading to an elevation in the copolymer's energy storage modulus (E') and glass transition temperature (Tg). Moreover, the Flynn‐Wall‐Ozawa (FWO) technique is employed to characterize and fit the non‐isothermal crosslinking kinetics of the ethylene‐acrylic ester derivatives, and the crosslinking activation energy is determined to lie between 97 and 140 kJ mol−1.

Inert Group-Containing Electrolyte Additive Enabling Stable Aqueous Zinc-Ion Batteries.

Aqueous zinc ion batteries (AZIBs) are considered promising energy storage devices because of their high theoretical energy density and cost-effectiveness. However, the ongoing side reactions and zinc dendrite growth during cycling limit their practical application. Herein, trisodium methylglycine diacetate (Na3MGDA) additive containing the additional inert group methyl is introduced for Zn anode protection, and the contribution of methyl as an inert group to the Zn anode stability is discussed. Experimental results reveal that the methyl group with various effects enhances the interaction between the polar groups in Na3MGDA and the Zn2+/Zn anode. Thus, the polar carboxylate negative ions in MGDA anions can more easily modify the solvation structure and adsorb on the anode surface in situ to establish a hydrophobic electrical double layer (EDL) layer with steric hindrance effects. Such the EDL layer exhibits a robust selectivity for Zn deposition and a significant inhibition of parasitic reactions. Consequently, the Zn||Zn symmetric battery presents 2375h at 1mAcm-2, 1mAhcm-2, and the Zn||V6O13 full battery provides 91% capacity retention after 1300 cycles at 3Ag-1. This study emphasizes the significant role of inert groups of the additive on the interfacial stability during the plating/stripping of high-performance AZIBs.

Preparation of molecularly imprinted polymer nanoparticles for selective adsorption of caffeine using dual-functionalized Ag2S quantum dots

Caffeine is the most abundant and widely consumed active medicinal compound, making it the most representative pollutant in the environment. This research involved synthesizing high-performance fluorescent HOOC-CC-functionalized Ag2S quantum dots (HOOC-QDs) measuring approximately 4.35 nm in size using the hydrothermal method. These QDs were then used to produce fluorescent molecularly imprinted polymer nanoparticles (MIP-Ag2S NPs) measuring 20.31 nm. The MIP-Ag2S NPs were created through a graft suspension copolymerization process involving methacrylic acid monomer, ethylene glycol dimethacrylate cross-linker, and caffeine template molecules. The polar carboxylic acid groups enhance the interaction with the template molecules, which is crucial for selectivity, and the -CC- groups aid in network formation. The MIP-Ag2S NPs emitted fluorescence at around 500 nm, which was significantly reduced after caffeine adsorption. The pH-sensitive MIP-Ag2S NPs had a maximum caffeine adsorption capacity of 488 mg/g at pH 6 and a maximum release of approximately 96% at pH 2.2. Additionally, repeated cycles of adsorption and desorption did not result in a significant loss of adsorption capacity. The HOOC-QDs can be used to prepare MIPs for extracting and recognizing pollutants and medicine in water and for controlled drug delivery systems.

Effects of surfactant with different injection times on asphaltene adsorption behaviors on the kaolinite surfaces: A molecular simulation study

The adsorption behavior of asphaltenes on the mineral surfaces seriously reduces oil recovery, which is dependent on the molecular structure, surface properties of the inorganic minerals, and the injection time of chemicals. In the present study, the molecular dynamics (MD) simulation is performed to construct the asphaltene-kaolinite adsorption systems and the 3-(N,N-Dimethyloctadecylammonio) propane sulfonate (DOPS) surfactant flooding systems to explore the effect of DOPS injection times on the detachment of asphaltene aggregates with discrepant adsorption characteristics. The number density distribution and the interaction analysis between asphaltene and kaolinite are employed to evaluate the adsorption behaviors of asphaltene on the kaolinite-liquid interfaces. The radial distribution function (RDF) describes the relative positions of the surfactants and asphaltene aggregates. The effective free energy and the independent gradient model based on Hirshfeld partition (IGMH) method further illustrate the microscopic mechanism of asphaltene detaching by the surfactant. The simulation results indicate that intensely polar carboxylate groups and polyaromatic rings with π-conjugated structures dominate the adsorption behavior of asphaltenes. The DOPS surfactants injected after the water flooding are difficult to produce effective ways of detaching asphaltenes, while the introduced DOPS surfactants during water flooding can generate DOPS-ASPn combinations to detach asphaltene from the kaolinite surfaces. This work first investigates the effects of surfactants with different injection times on the oil detachment efficiency at a molecular scale, further deepening the understanding of oil detachment process via surfactant flooding.

CIL-ExPMRM: An Ultrasensitive Chemical Isotope Labeling Assisted Pseudo-MRM Platform to Accelerate Exposomic Suspect Screening.

Exposome is the future of next-generation environmental health to establish the association between environmental exposure and diseases. However, due to low concentrations of exposure chemicals, exposome has been hampered by lacking an effective analytical platform to characterize its composition. In this study, by combining the benefit of chemical isotope labeling and pseudo-multiple reaction monitoring (CIL-pseudo-MRM), we have developed one highly sensitive and high-throughput platform (CIL-ExPMRM) by isotope labeling urinary exposure biomarkers. Dansyl chloride (DnsCl), N-methylphenylethylamine (MPEA), and their isotope-labeled forms were used to derivatize polar hydroxyl and carboxyl compounds, respectively. We have programmed a series of scripts to optimize MRM transition parameters, curate the MRM database (>70,000 compounds), predict accurate retention time (RT), and automize dynamic MRMs. This was followed by an automated MRM peak assignment, peak alignment, and statistical analysis. A computational pipeline was eventually incorporated into a user-friendly website interface, named CIL-ExPMRM (http://www.exposomemrm.com/). The performance of this platform has been validated with a relatively low false positive rate (10.7%) across instrumental platforms. CIL-ExPMRM has systematically overcome key bottlenecks of exposome studies to some extent and outperforms previous methods due to its independence of MS/MS availability, accurate RT prediction, and collision energy optimization, as well as the ultrasensitivity and automated robust intensity-based quantification. Overall, CIL-ExPMRM has great potential to advance the exposomic studies based on urinary biomarkers.

Manipulating the Thermal Conductivity of the Graphene/Poly(vinyl alcohol) Composite via Surface Functionalization: A Multiscale Simulation.

The reverse non-equilibrium molecular dynamics simulation is used to investigate the influence of functional groups (FGs) on the thermal conductivity of a graphene/poly(vinyl alcohol) (PVA) composite, which considers non-polar (methyl) and polar (hydroxyl, amino, and carboxyl) groups. First, the polar groups can be more effective to improve the interfacial thermal conductivity than the non-polar group. This can be explained well by characterizing the interfacial Coulombic energy, number and lifetime of hydrogen bonds, vibrational density of states, and integrated autocorrelation of the interfacial heat power. Moreover, the hydroxyl group can improve the interfacial thermal conductivity more than the other groups, which can be rationalized by analyzing the surface roughness of graphene and the radial distribution function of FGs and the PVA chains. However, the introduction of FGs destroys the graphene structure, which consequently reduces the intrinsic thermal conductivity. Furthermore, by adopting the effective medium approximation model and finite element method, there exists a critical graphene length where the overall thermal conductivities are equal for the functionalized and pristine graphene. Finally, the distribution state of graphene is emphasized to be more vital in determining the overall thermal conductivity than the generally accepted interfacial thermal conductivity.

An Amphiphilic Peptide Carrier for HCl Transport.

Single molecules that co-transport cations as well as anions across lipid membranes are few despite their high biological utility. The elegant yet simple lipidomimetic peptide design herein enables efficient HCl transport without the use of any external additives for proton transport. The carboxylic acids in the dipeptide scaffold provide a handle to append two long hydrophobic tails and also provides a polar hydrophilic carboxylate group. The peptide central unit also provides NH sites for anion-binding. Protonation of the carboxylate group coupled with the weak halide binding of the terminal NH group results in HCl transport with transport rates of H+ > Cl‾. The lipid-like structure also facilitates seamless membrane integration and flipping of the molecule. The biocompatibility, design simplicity and potential pH regulation of these molecules open up several avenues for their therapeutic use.

Roles of chemistry modification for surface wettability of Polyether-Ether-Ketone (PEEK) by ultraviolet laser ablation

Tailoring the functionality of Polyether-ether-ketone (PEEK) is critical for enhancing its application, which can be accomplished by the modification of surface morphology and chemistry. In the present work, we experimentally demonstrate the correlation of modified chemical composition of textured PEEK surface by 355 nm UV nanosecond pulsed laser ablation with enhanced surface wettability. Specifically, the impact of UV laser processing parameters on microgroove morphology and ablated surface quality of PEEK surface is evaluated, with which high precision grid surface textures with uniform ablation quality are fabricated. The modification of chemical elements and functional groups of textured PEEK surface by the laser ablation is further analyzed by XPS spectra characterization, which demonstrates the substantial change of C=O and O–C=O bonds, as well as freshly generated polar carboxylic acid groups. Experimental results indicate that the surface composition modification greatly increases surface polarity and surface free energy of textured PEEK surface accompanied by enhanced surface wettability.