A series of computational fluid dynamics–discrete element method (CFD-DEM) simulations were applied to seed flow in horizontal-vertical 90-degree elbows. The performance of one-way and two-way CFD-DEM coupling methods was compared. Additionally, simulated seed velocities were compared to the current pneumatic conveying theory for each coupling method. Simulated field peas (Pisum sativum) were pneumatically conveyed to study the effect of air velocity (20, 25, and 30 m/s), seed rate (0.07, 0.21, and 0.42 kg/s), elbow diameter, D, (48.3, 60.3, and 72.4 mm), and elbow bend radius (1.5D, 2.5D, 3.5D, and 4.5D) on seed attributes (trajectory, velocity, and force). Results showed that seed velocity was significantly different between one-way and two-way coupling. Both methods resulted in nearly identical seed trajectory and force. Overall, simulated seed velocities had a strong correlation to values calculated through the current pneumatic conveyance theory. Dimensional analysis revealed that seed contact force was proportional to the elbow diameter to the power of 0.26 and inversely proportional to the elbow bend radius to the power of 0.5. Simulation results indicated that one-way coupling could be suitable to describe seed flow when two-way coupling may not be possible or practical.