This study developed a numerical model for an ammonia/diesel dual direct-injection two-stroke engine and validated it based on engine bench test results. The engine combustion and emission characteristics were discussed under the cases of different injection parameters, intake temperatures, and exhaust gas re-circulation (EGR) rates. The findings indicate that altering the injection angle of ammonia and diesel sprays impacts the in-cylinder swirl and the ignition timing of the ammonia spray, consequently affecting the heat release phase of ammonia combustion. A suitable arrangement spray plumes can effectively reduce the emissions of unburned ammonia and greenhouse gas (GHG), while increase the emissions of NOx. On the other hand, higher intake temperatures can increase the average in-cylinder temperature, reducing unburned ammonia, N2O and GHG emissions. However, it also results in greater NO emissions, which can affect fuel economy negatively. Furthermore, the use of EGR technology can reduce the combustion temperature, thereby lowering the emission of nitrogen-based pollutants, but it also reduces ammonia combustion efficiency. By simultaneously applying the three aforementioned technologies within a certain range of conditions, it is possible to effectively synergize and control nitrogenous emissions and GHG while maintaining high thermal efficiency of ammonia/diesel dual direct injection engines.