This paper reviews and integrates new results on: (1) the Late Paleozoic and Mesozoic evolution of Central Asia; (2) Cenozoic mountain building and intramontane basin formation in the Altay-Sayan area; (3) comparison of the tectonic evolutionary paths of the Altay, Baikal, and Tien Shan regions; (4) Cenozoic tectonics and mantle-plume magmatic activity; and (5) the geodynamics and tectonic evolution of Central Asia as a function of the India-Himalaya collision. It provides a new and more complete scenario for the formation of the Central Asian intracontinental mountain belt, compared with the generally accepted model of the “indentation” of the Indian plate into the Eurasian plate. The new model is based on the hypothesis of a complex interaction of lithospheric plates and mantle-plume magmatism. Compilation and comparison of new and published structural, geomorphological, paleomagnetic, isotopic, fission-track, and plume magmatism data from the Baikal area, the Altay, Mongolia, Tien Shan, Pamir, and Tibe...