Cranioplasty is one of the oldest and most common surgeries. Cranioplasty materials developed with this surgery. Many kinds of material have been applied to cranioplasty such as gold, silver, aluminum, lead, platinum, titanium, autogenous bone, allograft, acrylic resin, polyethylene, silicone rubber, carol, ceramic, hydroxyapatite and calcium phosphate cement. In the past 60 years, autogenous bone, acrylic resin, silicone rubber, hydroxyapatite, phosphate cement, titanium sheet and computer-designed plastic ti-alloy plate are the most commonly used materials. Among the materials, computer-designed plastic ti-alloy plate is the preferred material. It is ideal cranioplasty material with high histocompatibility, plasticity and chemical stability, and which has not been found until now to be cytotoxic or immunogenic.