This paper presents a comprehensive approach aimed at developing a coupled process-structure simulation that integrates anisotropic and elastoplastic material behavior for plastic components manufactured through Fused Filament Fabrication (FFF) 3D printing. The simulation incorporates material orientation considerations, linking the process simulation with structural simulation. Subsequently, stress and strain values from the simulations are compared with the test results. Moreover, the fracture behavior of components manufactured in this way is also taken into account in relation to material orientation. The executed simulations have yielded successful outcomes, affirming the efficacy of the anisotropic and elastoplastic simulation across all strand orientations. Special attention is paid to the application of the method. Here, the simulation method introduced in this contribution with the approaches for describing the material behavior under mechanical load can be used in the future in the dimensioning of FFF manufactured plastic components to predict the deformation behavior and failure, especially under consideration of a well economic and efficient virtual product development.