Plasma Secretin Levels Research Articles

The effect of secretin on pancreatic glucoregulatory hormones in man.

Secretin was given intravenously to four normal men as a 150 U pharmacologic pulse. To an additional four men, during hyperglycemia, secretin was administered as a 5 U pulse with an infusion of 1.2 U per minute for 30 minutes, a rate shown to produce plasma secretin levels similar to those found after oral glucose load. Although insulin increased an average of 7 and 12 fold during the respective infusions, secretin did not significantly alter glucagon levels. These data suggest that, in humans, secretin influences glucose utilization by enhancing insulin release without producing a concomitant change in glucagon.

Diversion of pancreatic juice on gastric and pancreatic response to a meal stimulus.

ARTICLESDiversion of pancreatic juice on gastric and pancreatic response to a meal stimulusAR Cooke, DL Nahrwold, and MI GrossmanAR Cooke, DL Nahrwold, and MI GrossmanPublished Online:01 Sep 1967https://doi.org/10.1152/ajplegacy.1967.213.3.637MoreSectionsPDF (539 KB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInEmailWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformationCited ByRegulation of Pancreatic SecretionA secretin releasing peptide exists in dog pancreatic juiceLife Sciences, Vol. 66, No. 14Feedback Regulation of Pancreatic Exocrine Secretion in Minipigs8 July 2009 | Scandinavian Journal of Gastroenterology, Vol. 32, No. 4Gastrin-releasing peptide and CCK after intraduodenal inhibition of proteases in dogsInternational journal of pancreatology, Vol. 15, No. 3Role of secretin in negative feedback regulation of postprandial pancreatic secretion in dogsGastroenterology, Vol. 105, No. 2The importance of gastric secretion in the feedback control of interdigestive and postprandial pancreatic secretion in ratsRegulatory Peptides, Vol. 36, No. 1Is there a duodenum-pancreas negative feedback?International journal of pancreatology, Vol. 8, No. 4Alterations in Digestive Function Caused by Pancreatic DiseaseSurgical Clinics of North America, Vol. 69, No. 3Effect of Pancreatic juice and Trypsin on Oleic Acid-Stimulated Pancreatic Secretion and Plasma Secretin in DogsGastroenterology, Vol. 96, No. 5Pancreatic Secretion and the Release of Cholecystokinin after a Meal in Dogs with and without Exclusion of Pancreatic Juice8 July 2009 | Scandinavian Journal of Gastroenterology, Vol. 24, No. 4Pancreatic secretory response to ordinary meals: Studies with pure pancreatic juiceGastroenterology, Vol. 94, No. 2Bile exclusion from the duodenumDigestive Diseases and Sciences, Vol. 30, No. 10Effect of intraluminal bile on the feedback regulatory mechanism of pancreatic enzyme secretion in conscious ratsGastroenterologia Japonica, Vol. 20, No. 3Pancreatic bicarbonate response to food-bound hydrogen ion along the gutGastroenterology, Vol. 87, No. 3Regulation of Pancreatic SecretionClinics in Gastroenterology, Vol. 13, No. 3Morton I. Grossman, M.D. Ph.D.: An Oral HistoryGastroenterology, Vol. 83, No. 1Terbutaline inhibits pancreatic secretionJournal of Surgical Research, Vol. 30, No. 3The Effect of Duodenal Infusion of Bile on Plasma VIP, GIP, and Secretin and on Duodenal Bicarbonate Secretion22 February 2010 | Scandinavian Journal of Gastroenterology, Vol. 15, No. 8The Influence of Intraduodenal Administration of Pancreatic Juice on the Bile-Induced Pancreatic Secretion and Immunoreactive Secretin Release in Man22 February 2010 | Scandinavian Journal of Gastroenterology, Vol. 15, No. 824-Hour plasma secretin level and pancreatic secretion in dogPeptides, Vol. 1, No. 2THE INTESTINE AS AN ENVIRONMENT FOR HYMENOLEPIS DIMINUTAExocrine Pancreatic Secretion in Conscious Sheep13 May 2010 | Zentralblatt für Veterinärmedizin Reihe A, Vol. 26, No. 6Effects of a protein meal, intraduodenal HCl, and oleic acid on portal and peripheral venous secretin and on pancreatic bicarbonate secretion.Gut, Vol. 19, No. 4Neurohormonal control of pancreatic secretionGastroenterology, Vol. 74, No. 2Bile and pancreatic secretion in chickens: the effects of bile salts, feeding and acidComparative Biochemistry and Physiology Part A: Physiology, Vol. 61, No. 4Effect of small bowel resection on gastrin release, catabolism, and activity in dogsJournal of Surgical Research, Vol. 21, No. 4GASTRIC AND DUODENAL ULCER AND THEIR ASSOCIATED DISEASESThe Lancet, Vol. 307, No. 7961Effect of motilin on pancreatic secretionPflügers Archiv European Journal of Physiology, Vol. 364, No. 3The relationship of intestinal fat to an augmented acid and gastrin response in dogs with a reversible pancreatic fistulaJournal of Surgical Research, Vol. 18, No. 4Augmented acid and gastrin response to meals after pancreatic duct ligationJournal of Surgical Research, Vol. 16, No. 4Digestion and absorption of dry and high-moisture maize diets in the small and large intestine of the pig9 March 2007 | British Journal of Nutrition, Vol. 30, No. 03Gastrointestinal HormonesMedical Clinics of North America, Vol. 57, No. 4Concurrent studies on the flow of digesta in the duodenum and of exocrine pancreatic secretion of calves9 March 2007 | British Journal of Nutrition, Vol. 29, No. 3Secretin: A Long Progress NoteGastroenterology, Vol. 62, No. 2Failure of High Pco 2 in the Duodenal Bulb to Inhibit Gastric Acid SecretionActa Physiologica Scandinavica, Vol. 81, No. 3Effect of Secretin on Fasting and Postprandial pH of the Duodenal Bulb in DogsGastroenterology, Vol. 59, No. 1Effect of Vagotomy on the Canine Pancreatic Secretion after Feeding25 February 2010 | Scandinavian Journal of Gastroenterology, Vol. 4, No. 5 More from this issue > Volume 213Issue 3September 1967Pages 637-639 Copyright & PermissionsCopyright © 1967 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1967.213.3.637PubMed6036779History Published online 1 September 1967 Published in print 1 September 1967 Metrics