Dielectric Discharge Barrier (DBD) plasma actuators are considered as one of the best active electro-hydrodynamic control devices, and are considered by many contemporary researchers. Here a simple electrostatic model, which is improved by authors, and uses the Maxwell’s and the Navier–Stokes equations, is proposed for massive optimization computations. This model is used to find the optimum solution for application of a dielectric discharge barrier on a curved surface of a DU25 wind turbine blade airfoil, in a range of 5–18 kV applied voltages, and 0.5 to 13 kHz frequency range. Design variables are selected as the dielectric thickness and material, and thickness and length of the electrodes, and the applied voltage and frequency. The aerodynamic performance, i.e. the lift to drag ratio of the wind turbine blade section is considered as the cost function. A differential evolution optimization algorithm is applied and we have simultaneously found the optimized value of both geometrical and operational parameters. Finally the optimized value at each voltage and frequency are sought, and the optimum aerodynamic performance is derived. The physical effect of each design variable on the aerodynamic performance is discussed. A design relation is proposed to recommend an optimum design for wind turbine applications.