Customized insoles are generally prescribed to treat or prevent gait modifications and biomechanical changes related to foot deformities that can cause abnormal foot load. These orthoses have the aim of reducing excessive plantar pressures or providing stability or increasing contact area and comfort [1]. Digital scanning, computer-assisted surface modeling techniques, and additive manufacturing are the latest developments in orthotic production. These technologies enable traditional manufacturing processes and designs to be digitalized with control and precision [2]. However, these methods have some limitations: they are still based on the experience of orthopedic technicians [3], only static or bare foot pressure is obtained, unloaded foot shapes are created or inappropriate materials are used for CAD-CAM processing. To overcome these limits, the goal of this study was to develop a method for producing 3D-printed orthoses from plantar pressure data collected through sensorized insoles during walking. A patient with a flat foot was asked to walk barefoot on a treadmill (2 km/h) and then with his shoes on the floor (at self-selected speed), at the orthopedic manufacturer's site during the regular assessment for the production of plantar insoles. Plantar pressure data were acquired both by the instrumented treadmill (I-Runner, Impronta Medica) and by plantar pressure insoles into the shoes (PedarX, Novel gmbh). Afterwards, two different workflows were used to design and produce orthopedic insoles: (1) manufacturer routine methods have been applied, which involves collecting footprints on the instrument treadmill, processing the plantar pressure map through the software Freestep and Easycad Insole (Sensor Medica), producing the insole with the CAD-CAM milling technique; (2) new method involves the use of PedarX data, processed through self-developed codes, and a stl surface generation based on these plantar pressure data. This stl was further processed through the free 3D modeling software Blender and EasyCAD, then the insole was printed with a 3D printer (Bioflex material, straight filling, 90% infill). In Fig. 1 is represented the pipeline of the new method (2). The final result was promising. Since there are no manual interventions by technicians capable of injecting subjectivity into the final product, it ensures that it can be easily reproduced and is consistent with the previously created 3D model. In addition, the possibility of generating the plantar orthosis model from plantar pressure insoles, enables the necessary data to be obtained under free conditions, taking into account the relationship between the foot and the shoe, without the constraints of an instrumented treadmill. As development progresses, comparisons between the two methods of producing insoles will be made, and new filling materials and different filling percentages will be studied to optimize 3D printing.