Planning Program Research Articles

Klasterisasi Peserta KB Aktif di Desa Kalirejo Lawang Menggunakan Metode K-Means

The Family Planning (KB) program in Kalirejo Lawang Village faces challenges in the process of clustering active participants, which is time-consuming and prone to errors. Based on these challenges, a clustering solution using the K-Means algorithm was proposed. Experiments were conducted by testing the number of clusters from 2 to 8 and evaluating them using the silhouette score. The results of the study showed that the optimal number of clusters is two, as indicated by a silhouette score of 0.447. This value represents the best clustering quality compared to other cluster numbers, where the scores for clusters 3 to 8 did not exceed this value. This demonstrates that clustering into two groups provides the most optimal results. Lower scores for clusters 3 to 8 indicate that dividing the clusters into more groups did not create clear separations or worsened the cohesion within clusters. The conclusion of this study shows that the K-Means method can be applied and is reliable for clustering active KB participants in Kalirejo Lawang Village. With its speed and accuracy, K-Means offers a significant solution to improving the efficiency of the KB program at the village level. The practical implication of this research is to provide a more structured basis for planning and decision-making in the KB program at the village level. These findings mark an important step in optimizing the management of KB program data, opening opportunities for broader implementation in other areas.

Instruments for Value Elucidation in Older Adults in Clinical Practice-A Scoping Review.

To ensure appropriate care for the individual older adult, an ideal treatment should align with patients' values. However, healthcare professionals struggle with how to elucidate patient values effectively. To offer guidance to healthcare professionals, we performed a scoping review, thereby mapping and categorizing instruments specifically developed to elucidate values of older adults in clinical practice. A systematic search was conducted from inception up to October 2023 in PubMed, Psychinfo, CINAHL, and Cochrane Library. Articles on instruments clarifying older adults' values in a clinical setting were included. Articles on instruments elucidating patients' wishes, preferences, or goals were excluded. After screening 7759 eligible studies, we included 37 studies outlining unique instruments. Instruments were subdivided into the following categories, based on the setting in which the instruments were used: "instruments with a general scope," "health record-based interventions," "advance directives," "advance care planning programs," and "decision support tools." Values were made plain in different ways, and instruments promoted different approaches. We further categorized these approaches alongside different axes: "open versus closed," "process-oriented versus decision-oriented," "confronting versus nonconfronting," and "explicit versus implicit." Some instruments focused on establishing a process of deliberation, whereas others focused on achieving treatment decisions. We found and categorized a large range of instruments, which promoted different ways to elucidate older adults' values. This scoping review serves as an introduction for healthcare professionals to available instruments, which help to clarify patients' values. By categorizing the instruments along different axes of approaching value clarification, we offer healthcare professionals guidance for selecting an appropriate instrument.

IMPLEMENTASI PROGRAM PENCEGAHAN HUMAN IMMUNODEFICIENCYVIRUS/AQCQUIRRED IMMUNODEFICIENCY SYNDROME (HIV/AIDS) PADA PUSKESMAS PARINGIN SELATAN KABUPATEN BALANGAN

To prevent and overcome HIV/AIDS cases in Balangan Regency,the implementation of prevention programs at the South Paringin Health Center still faces several challenges.Community stigma and discrimination against this disease are still high, and the lack of infrastructure such as leaflet counseling media is an obstacle. This study used qualitative descriptive method involving 14 respondents.Data were collected through interviews, observation, and documentation, and analyzed using a variety of analytical techniques.The results showed that the HIV/AIDS prevention program at Puskesmas Paringin Selatan was effective, but there was still a lack of resources and communication. Factors supporting program implementation include policy stakeholder commitment, cross-program and cross-sector involvement, and community participation. However, stigma and societal discrimination are inhibiting factors. To improve program implementation, it is recommended that the Health Office and Puskesmas program managers strengthen information about HIV/AIDS, at-risk groups conduct routine screening,and communities participate in the planning and implementation of this prevention program.

Aggression in crime and sports: a study on prisoners and amateur combat athletes in Türkiye

BackgroundThis research focuses on examining and comparing the aggression levels of prisoners incarcerated for intentional injury and amateur combat athletes. The study aims to explore the differences in aggression levels among these groups to understand the impact of incarceration and sports participation on aggression.MethodsThe participants included in the analysis consist of prisoners (n = 363) housed in Marmara No. 7 and No. 3 Type L Closed Penal Institutions, who have been incarcerated for intentional injury, with an average age of 36.64 ± 10.30 years and an average custody period of 980.47 ± 1335.27 days. Amateur combat athletes (n = 203) with an average age of 25.17 ± 10.09 years have been actively engaged in sports for an average of 11.83 ± 9.53 years. The control group (n = 329) has an average age of 32.65 ± 7.56 years. Data collection instruments included a personal information form and the Buss-Perry Aggression Questionnaire. The data were analyzed using IBM SPSS Statistics 23.0, with a significance level set at p < 0.05.ResultsAnalysis of the Buss-Perry Aggression Questionnaire scores revealed that the aggression levels of prisoners incarcerated for intentional injury were statistically significantly lower than those of both amateur combat athletes and control group participants (p < 0.001). Additionally, a significant reduction in overall aggression scores was observed among prisoners as the number of days in custody increased (p = 0.045). No significant differences were found among amateur combat athletes concerning the discipline variable, and no meaningful relationship was identified between years of active sports participation and aggression scores.ConclusionThe findings indicate that educational, social, and sports activities organized in correctional facilities can be effective in reducing aggression levels among inmates. Systematic planning, professional implementation, and continuous evaluation of such programs can make significant contributions to the rehabilitation of prisoners and their successful reintegration into society.

A Bildung theoretical framework for Models-based Practice in physical education

ABSTRACT Background: Models-based Practice (MbP) has gained popularity in the literature on physical education. It offers a comprehensive approach to teaching and programme planning. However, MbP lacks a solid theoretical foundation to guide reflections on educational purposes, teaching methods and learning aspirations. Purpose: This paper proposes a framework to address this shortcoming by drawing on Wolfgang Klafki's theory of general Bildung. The goal is to provide a theoretical foundation for MbP and contribute to its further development. By exploring the potential of a Bildung theoretical framework for MbP, this paper also seeks to bridge the gap between the Anglo-American tradition that MbP adheres to and the Continental tradition of Bildung. Relevance and Implications: The analysis demonstrates how Bildung theory can complement and challenge elements in MbP. First, it can contribute with an overarching educational purpose, which is to develop the capacity for self-determination, co-determination, and solidarity. Second, the principle of exemplarity can secure alignment between the main themes of models and epochal key problems. Third, the principles of non-affirmativity and versatility can inform learning aspirations for students, and the principle of multidimensionality can inform a multi-model approach where students engage with different body-cultural practices. Fourth, the principles of autonomy and interdependency can inform the pedagogical work of teachers. Conclusion: We conclude that, on the one hand, MbP can serve as a framework for integrating the educational principles of Bildung in schools, enriching the pedagogical landscape of physical education. On the other hand, Bildung theory can provide a solid theoretical framework for MbP, as it underpins several strengths of the approach and can guide its future development. Thus, MbP can provide a practical framework for working with general Bildung in physical education, while Bildung theory can provide a theoretical framework with criteria for the development and use of pedagogical models in MbP that align with democratic and educational objectives.

Peningkatan Kapasitas Pengelola Kampung Edukasi di Desa Kembangkuning, Kabupaten Boyolali

In the development process in the era of globalization, empowerment is a very important form of development. The institutional partner in this service is Kembangkuning Village with Kampung Edukasi as the program implementation partner. The aim of this service is to improve the quality of service from partners who have been engaged in educational tourism. The implementation method is carried out in several stages, namely: situation analysis, program planning, implementation and evaluation. The results of the activities that have been carried out show that the potential for partner development is divided into two aspects, namely educational and industrial-based tourism. Partners have experienced an increase in quality in terms of understanding efforts to provide excellent service to every visitor. The digitization aspect is carried out through the development of a website and also barcodes for each collection in the museum.

Uncovering the Life Experiences Being Fathers of Children With Cerebral Palsy.

This research aims to uncover the life experiences of fathers of children with Cerebral Palsy (CP) in Indonesia. This study utilized a descriptive phenomenological approach. Nine fathers of young children and adolescents with CP were purposively recruited and were interviewed in-depth between June and August 2023. Data were analysed by using Giorgi's descriptive phenomenological approach. Our study identified three main themes: uncovering the meaning of being a father, expectations and hope for children's growing up, and the challenges of being a father. These themes were further divided into 10 sub-themes. Our research suggests that fathers consider having a disabled child as a gift and a test from God, and they hold specific meanings about being a father that gives them strength. Fathers are responsible for taking care of their children and not neglecting them. They have expectations and hopes for their children to become independent and successful, with the skills needed to make a living. Fathers face many challenges, such as dividing their time between work and family and figuring out how to stimulate their children's motor skills. The research indicates that involving fathers in caring for children, particularly those with CP, has significant implications for program planning and service delivery. Therefore, professionals should integrate fathers' role in planning and delivering services for childcare.

Risk Factors for Adults with Chronic Obstructive Pulmonary Disease in the United States, Utilizing State-Based Surveillance

Chronic Obstructive Pulmonary Disease (COPD) is a complex and heterogeneous condition. Exposure to tobacco smoke and air pollutants are key risk factors for COPD development; however, other risk factors include race/ethnicity, sex of adults, a history of asthma, occupational exposures, and chronic respiratory infections. Data for the current study were from the 2022 Behavioral Risk Factor Surveillance Survey. Chi-squares and multinomial logistic regression analyses, adjusted with the survey’s sampling weight, were used to examine how critical health indicators impacted a COPD diagnosis. Participants (N = 311,175) were adults aged 45 years and older. Adjusted multinomial regression analyses showed adults who reported asthma, current and former smoking, poor physical health, depression, less physical activity, and fatigue were more likely to report COPD. Those with COPD were more likely to be male than female. Moreover, those with COPD reported higher rates of health insurance coverage, and yet had lower income and more financial difficulty affording a doctor for health services. In a follow up regression analysis, examining racial differences in COPD for participants, American Indian adults had a higher odds of reporting COPD than the “other” race groups. Because COPD remains a leading cause of death and disability in the U.S., and racial disparities persist in respiratory outcomes, continuing to identify risk factors for vulnerable groups could assist health program planners with development of successful health messaging.

THE EFFECTIVENESS OF THE FAMILY PLANNING PROGRAM IN CONTROLLING THE POPULATION GROWTH RATE IN NORTH MINAHASA REGENCY, NORTH SULAWESI PROVINCE

This research aims to assess the effectiveness of the Family Planning Program in controlling the population growth rate in North Minahasa Regency, North Sulawesi Province. The research employs a qualitative descriptive method to collect and analyze data, with a total of 9 informants. Data collection was conducted through observation, interviews, and documentation. The data analysis process involved reduction, presentation, conclusion, and verification. The research is grounded in Duncan's theory of effectiveness, which consists of three components: (1) Goal Achievement, (2) Integration, and (3) Adaptation. The findings indicate that the Family Planning Program has effectively reduced the population growth rate in North Minahasa Regency by 0.6% compared to the previous year. The success of the program can be attributed to efforts to address various challenges, including enhancing human resource competency through training, conducting continuous socialization during key family-related events, and improving infrastructure, such as providing transportation to facilitate access to services for family planning participants. Keywords: Effectiveness, Family Planning Program, Population Growth Rate

Effectiveness of Installment Payment Plan Program through Face-to-Face Service Channels and Non-Face-to-Face Service Channels

This study evaluates the effectiveness of registration services for BPJS Kesehatan's REHAB (Installment Payment Plan) program through face-to-face channels at branch offices and non-face-to-face channels via the Mobile JKN application. Employing a qualitative descriptive design, data were collected from 33 informants, including frontline coordinators, frontline staff, UP3KC staff, and 30 participants using purposive sampling. Data collection methods comprised interviews, observations, and documentation, with data validity ensured through triangulation. Analysis followed Miles, Huberman, and Saldana’s interactive model, involving data reduction, presentation, and conclusion verification. Results indicate that the Mobile JKN application is the preferred registration channel due to its convenience and practicality. At the same time, face-to-face services are utilized as a backup option during technical disruptions. However, challenges such as incorrect participant data and system reliability hinder registration. This study underscores the need for improvements in the Mobile JKN system, particularly in data validation and technical stability, to enhance service accessibility and ensure seamless participant registration

Mitigating the Risks of Enterprise Software Upgrades: A Change Management Perspective

Enterprise software upgrades are crucial for maintaining competitive advantage, ensuring security, and enhancing operational efficiency. However, these upgrades often pose significant risks, including system disruptions, data loss, and user resistance. The problem lies in effectively managing these risks to avoid operational setbacks and ensure successful adoption. This paper explores the role of change management in mitigating these risks by offering solutions through strategic planning, stakeholder engagement, and comprehensive training programs. The research employs a mixed-methods approach, integrating quantitative survey results from 185 participants and qualitative insights from 20 in-depth interviews. Results indicate that organizations prioritizing stakeholder engagement, tailored training, and proactive communication achieve higher user satisfaction, improved system performance, and enhanced operational efficiency. These findings provide a framework for best practices in change management that minimize risks and promote successful software upgrades.

VOLUNTARY CHILDLESS SEBAGAI PILIHAN TAHDID AL-NASL UNTUK MEWUJUDKAN KELUARGA BERENCANA DALAM PERSPEKTIF HILAH

The background of this study is the childfree phenomenon that has re-emerged in the public eye amidst the decline in the ideal age marriage rate and the still high rate of early marriage. This study describes the phenomenon of voluntary childlessness, or the absence of children as an option in the context of tahdid al-Nasl (birth control) to realize family planning, with a hilah perspective approach. The focus of the study is the application of hilah in the case of voluntary childless couples who assume that they have supported the family planning program with their willingness to live without children so that they are able to reduce the birth rate. This study is normative with a literature study approach to collect primary legal materials. The results of this study indicate that voluntary childlessness is included in the hilah ghair syar'iyyah, or cases that are not permitted; the practice of family planning is permitted in Islam, but there are terms and conditions for its implementation and the goals to be achieved.

A descriptive summary of the WHO availability assessments of medical abortion medicines in eight African countries

BackgroundThe use of medical abortion using either a combination of mifepristone and misoprostol, or misoprostol alone has contributed to increased safety and decreased mortality and morbidity. The availability of quality medical abortion medicines is an essential component in the provision of quality abortion care. Understanding the factors that influence the availability of medical abortion medicines is important to help in-country policymakers, program planners, and providers improve availability and use of medical abortion.MethodsUsing a national assessment protocol and an availability framework, we assessed the availability of medical abortion medicines across five elements (Registration & Quality Assurance, Policy & Financing, Procurement & Distribution, Provider Knowledge, and End-user Knowledge) in eight countries: Botswana, Burkina Faso, Central African Republic, Democratic Republic of the Congo, Eswatini, Lesotho, Namibia and Uganda between November 2020 and November 2021. The assessment included an online desk review and virtual or telephone-based key informant interviews.ResultsRegistration of medical abortion medicines—misoprostol or co-packaged mifepristone and misoprostol products (combi-pack)—was established in all countries, except the Central African Republic. In Lesotho and Eswatini, the national regulatory agency is still in development and importation of Cytotec™ misoprostol is permitted for off-label use in obstetrics/gynecology. Misoprostol was included in all countries’ essential medicines lists, except Botswana. Burkina Faso and Democratic Republic of the Congo also include mifepristone on their essential medicines list and medical abortion regimens in national abortion care service and delivery guidelines. Additionally, guidelines clarified health worker roles in the provision of abortion care specific to the legal context of each country and permitted task-shifting of abortion service provision. Where guidelines did not exist, medical abortion medicines and their use were not well integrated into the public health care system. Community awareness activities on abortion rights and services have been limited in scope across the countries assessed, however, end-users' awareness of misoprostol as a medical abortion medicine was reported.ConclusionThe national landscape assessments identified several cross-cutting opportunities to improve availability of medical abortion medicines, including importing quality-assured medical abortion medicines; developing nationally approved abortion service and delivery guidelines that optimize healthcare worker roles; and expanding communication strategies to reach end-users and pharmacists.

Strategi Pengembangan Atribut Green City Kota Malang

A green city is a city with good planning that has an environmentally friendly character and seeks to manage its resources for everything that focuses on environmental balance. In an effort to create a green city, various planning and implementation programs have been and are being carried out, both by the government, private sector and also the community in order to realize the concept of a green city. One form of sustainable program to support, this is known as the Green City Development Program (Program Pengembangan Kota Hijau) or more easily abbreviated as P2KH which refers to the Regional Spatial Planning Plan (Rencana Tata Ruang Wilayah) or abbreviated as RTRW. Green cities themselves have indicators called eight (8) green city attributes, including: green open space, green waste, green transportation, green water, green energy, green building, green community, and green planning and design. The background on this research is presented in three criteria, including empirical problems, theoretical frameworks, and legal foundations used as references or legal guidelines for implementing the green city concept. It is known that the complexity of society's demands increases as the population increases. This of course becomes a challenge in managing environmental resources. Problems such as traffic jams, air pollution, increasing volumes of waste, slums, flooding and other social inequality problems, which of course with the increasing population, logically result in the living area becoming increasingly narrow. What happened in Malang City is no exception. Malang City has great potential for better services, especially in the context of realizing a green city. The research results show that there are eight green city attributes that have been implemented in several activities in Malang City. In practice, these eight attributes need continuous development. The concept of a green city is not a simple concept that can be planned once and then realized, it is a holistic, continuous and sustainable concept. Therefore, this research provides an in-depth look at strategies for developing green city attributes in Malang City using a qualitative approach. The strategy for developing green city attributes in the city of Malang is carried out through the SOAR and SWOT analysis stage, the development stage, the role enhancement stage, the support and development stage of appropriate technology, coordination and synergy between actors, as well as evaluation and supervision in improving the quality of the green environment and public awareness of development of the green city concept in Malang City.

Perceptions on circumcision for HIV prevention: an application of the health belief model in a qualitative enquiry among young men in Eswatini

ABSTRACT Voluntary medical male circumcision (VMMC) was identified as an effective strategy in HIV prevention. Although circumcision reduces heterosexual acquisition of HIV by 60%, there is low uptake of VMMC services in Eswatini. This study applies the health belief model (HBM) in understanding perceptions of young men in Eswatini towards VMMC for HIV prevention to upscale its adoption. A qualitative design was followed. Uncircumcised males aged 20–29 years were recruited among university students. In-depth interviews were conducted, transcribed verbatim, and transcripts imported into NVivo12 for line-by-line analysis. Emerging codes were categorized under major constructs of the HBM. Condomless sex, having multiple sex partners, genital caressing and being uncircumcised were seen as susceptible exposure. Taking life-long treatment and stigma were perceived as severity. However, participants had no intent to circumcise in the near future even after acknowledging the severity. Hygiene, prevention of sexually transmitted infections including HIV were perceived as main benefits. Fear of pain was perceived as key barrier impeding adopting circumcision and seemed to outweigh the benefits for some participants. These findings will assist programme planners to review and promote VMMC services that will improve good health and well-being of young men to avert HIV new infections in Eswatini.

Preoperative planning programme in minimally invasive lung surgery reduces intraoperative adverse events.

While minimally invasive surgery (MIS) is the preferred approach in patients with early-stage lung cancer, intraoperative adverse events (IOAE) may still occur. The objective of this study was to assess the impact of a dedicated preoperative planning program on adverse event occurrence. A single-centre cross-sectional comparative study was conducted, including all patients with proven/suspected lung cancer undergoing curative MIS, prior (September 2021-October 2022) and after (November 2022-January 2024) the implementation of a preoperative planning program. The preoperative planning program consisted of a weekly assessment of upcoming surgical cases, evaluating surgical strategy, anatomical variations and anticipating surgical difficulties. Data were prospectively collected. The primary outcome was the rate of IOAE. Secondary outcomes were conversion rate, healthcare-associated adverse events and postoperative morbi-mortality. We included 553 patients, 290 without preoperative planning and 263 undergoing a preoperative planning program. The overall IOAE rate was 11.4%, significantly lower after preoperative planning (7.6% vs 14.8%, P = 0.008). The overall healthcare-associated adverse events rate was 23.2%, significantly lower after preoperative planning (17.1% vs 28.6%, P = 0.0014). There were no statistical differences before and after preoperative planning for conversion rate (8.37% vs 10.7%, P = 0.354), complication rate (33.1% vs 34.5%, P = 0.73) and 90-day mortality (0.38% vs 2.07%, P = 0.126). Preoperative planning program impacted surgical strategy in 61/263 patients (23.2%) including a change in the extent of resection in 25/263 patients (9.5%). Implementation of a systematic preoperative planning program in MIS for lung cancer decreases IOAE enabling an improvement in surgical safety.

Assessment of dietary intake and its determinants in adult patients on anti-tubercular treatment in Aligarh, India: a cross sectional study

Background and objectives: Adequate nutrition and a good dietary practice play an important role in recovery from tuberculosis (TB). Improper dietary practice and poor nutrition lead to low immunity in the host and thus increase the risk of active TB in addition to relapse and mortality. The objective of the study was to assess the dietary intake and its determinants in patients on anti-tubercular treatment. Materials and methods: A cross-sectional study was conducted, in four Designated Microscopic Centres under the administration of the District TB Cell of Aligarh district from January 2020 to December 2021. Adult TB patients undergoing treatment between the ages of 18 to 60 years were enrolled. A semi-structured questionnaire was used as a study tool. The 24-hour recall method was used for eliciting dietary intake as it had less recall bias. The sufficient and insufficient dietary cut offs were chosen from the Indian Council for Medical Research (ICMR) nutrient guidelines for TB patients. The data was analyzed by appropriate statistical tests. Results: A total of 410 TB patients participated in the study. Majority (61.7%) of the patients were unemployed and 46.8% belonged to the lower middle class. Of the total cases, 83.2% patients were consuming energy below the Recommended Dietary Allowance (RDA). The protein intake was sub-optimal in 71%, while 52% were taking fat below RDA. Age, gender, and education of the participants were significantly associated (&lt; 0.05) with their energy and protein intake. Conclusions: The participants’ intake of nutrients was suboptimal compared to RDA. Thus, there is a need to improve the nutritional status of TB patients. Therefore, findings of the study could be utilised to plan programs for improved nutritional care for under privileged TB patients living in rural and urban areas. *Correspondence: S. Danish Iqbaal, Senior Resident, Department of Community Medicine, Indira Gandhi Institute of Medical Sciences, Patna-800014, Bihar, India. Email: iqbalsdalig@gmail.com; © 2025 The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License(CC BY 4.0).

COMMUNICATION PROGRAM PLANNING STUDY: THE EFFECT OF THE USE OF CHATGPT ON EDUCATION TO ENCOURAGE RESPONSIBLE AND ETHICAL LIFELONG LEARNING

Technology, which continues to develop along with the advancement of science, plays a key role in improving the understanding of science in education. Artificial intelligence (AI) is playing a key role in the transformation of education, and ChatGPT, as a generative language model, opens up new opportunities for innovative learning experiences. The determination of strategies in communication planning is always related to the elements of communication. The purpose of this study is to find out how the role of Communication Program Planning Studies has the Influence of the Use of ChatGPT on Education to Encourage Responsible and Ethical Lifelong Learning. The research method uses a descriptive qualitative method. The data used is secondary data, the researcher uses 16 articles and appropriate books as a reference in writing scientific papers. The results of this study show that the presence of ChatGPT is the result of the implementation of communication program planning that has received a positive response from various circles, namely students, students, and educators.

Preimplantation genetic testing for structural rearrangements by genome-wide SNP genotyping and haplotype analysis: a prospective multicenter clinical study.

Preimplantation genetic testing for chromosomal structural rearrangements (PGT-SR) has been widely utilized to select euploid embryos in patients carrying balanced chromosomal rearrangements (BCRs) by chromosome copy number analysis. However, reliable and extensively validated PGT-SR methods for selecting embryos without BCRs in large-cohort studies are lacking. In this prospective, multicenter, cohort study, carriers with BCRs undergoing PGT-SR were recruited across 12 academic fertility centers within China. PGT-SR was performed using genome-wide SNP genotyping and haplotyping approach. Parental haplotypes were phased by available genotypes from a close relative or an unbalanced embryo. The karyotypes of embryos were inferred from the haplotypes. Only a single embryo was transferred in each cycle. Between April 2018 and March 2023, 1298 carriers we randomly enrolled. A total of 7867 blastocysts from 1603 PGT-SR cycles were biopsied, in which 7750 (98.51%) were successfully genotyped and analyzed. Overall, 75.98% (1218/1603) of cycles obtained euploid embryos and 53.15% (852/1603) generated non-carrier embryos. The proportion of carrier and non-carrier embryos was similar in different subgroups. A total of 1030 non-carrier and 439 carrier embryos were transferred, 817 healthy babies were delivered cumulatively. Our results demonstrate that SNP-haplotyping method is highly accurate (sensitivity 95% CI: 98.34%-100%, specificity 95% CI: 96.63%-100%, respectively), and can be applied universally to different BCR types. Moreover, the clinical outcomes were comparable between the carrier and non-carrier embryo groups. This study demonstrates the effectiveness of preimplantation genetic genome-wide SNP-genotyping and haplotyping method, resulting in the delivery of more babies with a normal karyotype. This study was funded by the National Key Research and Development Program of China (2022YFC2703200, 2021YFC2700600, 2021YFC2700500), National Natural Science Foundation of China (82201807, 82171639, 82071717). Shanghai Science and Technology Innovation Action Plan Program (18411953800), and the Municipal Human Resources Development Program for Outstanding Young Talents in Medical and Health Sciences in Shanghai (2022YQ075).

Late antenatal care booking and associated factors among pregnant women in Ethiopia: evidence from 2019 performance monitoring for action data analysis

IntroductionPregnancy is a crucial period for a woman, her family, and society. Early initiation of antenatal care (ANC) follow-up helps to identify pre-existing health conditions and complications arising during pregnancy. It also allows the mother to receive health promotion and disease prevention services. On the other hand, late initiation or missing of ANC follow-up may lead to transmission of the infections to their fetus, stillbirth, anemia, congenital malformation, and congenital syphilis. This study aims to determine the magnitude and determinant factors of late ANC booking in Ethiopia.MethodsThe 2019 Ethiopia Performance Monitoring for Action (PMA) cross-sectional survey data was used for this study. It is a multistage cluster, nationally representative household survey. A total of 709 pregnant women were eligible for our study. The results of this study were presented as narrations, frequency tables, and graphs. Variables with p-value < 0.2 in univariable logistic regression were taken to a multi-variable logistic regression analysis and in the final model variables with Adjusted Odds Ratio (AOR) at 95% confidence interval and p-value of ≤ 0.05 were identified as predictor variables of late antenatal care booking.ResultsThe overall prevalence of late ANC booking was 54.28% (95% CI: 48.85, 59.49). Women who never attend formal education (AOR = 0.16 95% CI: 0.13, 0 0.67), women whose parity was 1 or 2 (AOR = 2.30, 95% CI: 1.05, 4.53) and women with wanted pregnancies (AOR = 1.80, 95% CI: 1.73, 4.32) were significant variables associated with late antenatal care booking.ConclusionIn Ethiopia, over half of the pregnant mothers initiated their ANC follow-up late and it is high as compared to the WHO recommendation. Unwanted pregnancy, being uneducated, and parity I or II were the factors for late ANC booking. Hence, it is important to provide health education on the timing of ANC among women within reproductive ages. Priority should be given to women with low levels of education, women who have one or more parity, and women with unplanned pregnancies. Family planning or birth spacing programs should be enhanced to prevent unwanted pregnancies.