Musculoskeletal injuries in horses are the main cause of retirement, rest, and death. To understand these injuries, it is necessary to study loads in muscles, tendons and ligaments. A musculoskeletal model makes it possible to consider all structures simultaneously and avoids invasive measurements. At present, most computational models of the equine limb described in the literature have been limited to the distal limb. The aim of this study was to create a preliminary musculoskeletal model of the whole equine forelimb and to run it with kinematic data collected during gait. The model was developed with the AnyBody Modelling System. It includes six limb segments, 11 muscle groups and 17 ligaments. Kinematic data were collected from the right forelimb of four Thoroughbreds at trot, right and left lead canter, and were then used in the model to compute sagittal plane joint excursions and ligament and tendon strains. The modelled joint excursions were in reasonable agreement with previous reports in the literature despite breed, gait and surface differences. Strain patterns of the tendons of the suspensory apparatus agreed with the literature, with maxima in mid-stance or at the end of stance. Strains in the distal palmar ligaments peaked in mid-stance, while strain in lacertus fibrosus peaked at the stance-swing transition. Tendon and ligament strains at canter were greatest when the measured forelimb was the trailing limb. Strain amplitudes varied against earlier models and these differences are discussed in relation to variations in methods, and especially in relation to attachment points of tendons and ligaments.