A compact ultra-wideband planar monopole antenna with a size of 22 mm by 34 mm is presented to achieve the quintuple-band-notched characteristics. The proposed antenna consists of a Mickey-mouse shaped radiating element, a truncated/smoothed ground plane and a microstrip feed-line. The quintuple-band-notched function is achieved by integrating five specially designed half/one-wavelength M-shaped resonators into the radiator, feed-line and ground plane. The simulated and measured results show that the proposed antenna is able to operate from 2.24 to 10.8 GHz for |S11| < −10 dB with excellent band rejection performance in the frequency bands of 2.35 to 2.61 GHz, 3.16 to 3.69 GHz, 5.0 to 6.1 GHz, 7.2 to 7.7 GHz and 8.1 to 8.74 GHz for some existing communication systems such as wireless local area networks, worldwide interoperability for microwave access, downlink of X-band satellite communication and ITU 8-GHz band, respectively. In addition, both the frequency-domain and time-domain performances of the antenna are investigated by simulation and measurement. The results obtained are also in very good agreement.