Due to their high reliability and precision, piston valves are frequently used for pressure regulating applications. Particularly in the aerospace industry, where cryogenic fluids such as liquid hydrogen are frequently used, the design and operation of piston valves become crucial. The current state of advancement of this technology in the cryogenic field is still in its early stages, owing to the difficulties in designing such complex systems in harsh environments. This justifies the need for further in-depth studies and analysis using CFDs tools and predictive models. In order to ensure an optimal and efficient use of a piston pressure regulating valve in cryogenic environment, it is necessary to understand the strengths and limitations of this technology in an extreme thermal and mechanical condition. The presented work concentrates therefore on a preliminary analysis and optimization of a piston valve operating in liquid hydrogen flow field, for pressure regulating applications. Particular focus will be dedicated to the overall dynamics of the main body of the piston, in terms of robustness and controllability of the desired response of the system. The dynamics of the piston within an extremely low-viscous flow, as well as the thermodynamic and fluid dynamic aspects of the valve system, will be discussed. Simulations of the flow field will be performed through CFD tool, crossing the results with the dynamics of the simulated system response through and implemented Simulink model. The obtained results will be then critically analysed in order to suggest possible optimization of the valve in the locations where the system is most affected from a thermal and mechanical standpoint.