Objective to systematically evaluate the efficacy of Pilates exercises for nonspecific low back pain. Methods Computerized searches of CNKI, Wan fang Data, VIP and PubMed, EM base, and Web of science databases for randomized controlled trial studies on risk factors for NLBP published since the database was created until March 1, 2022. Literature extraction and risk of bias evaluation were performed independently by 2 investigators, and Meta-analysis was performed using RevMan5.4 software. Results A total of 14 included RCTs containing 975 patients were included. Meta-analysis results showed that in terms of relief of low back pain, VAS scores in the Pilates exercise group were statistically significant compared to other muscle group training [MD=-1.71, 95% CI (-3.86,0.45), Z=1.55, P=0.003<0.05], while compared to other exercise workouts [ MD=0.25, 95% CI (-3.72,4.21), Z=0.12, P=0.9>0.05] and medication and physical therapy [MD=-1.15, 95% CI (-2.75,0.46), Z=1.40, P=0.16>0.05] were not significantly different compared to other exercise workouts [ MD= -0.55, 95% CI (-1.16,0.06), Z=1.76, P=0.08>0.05] and routine care and missionary group [MD=-0.85, 95% CI (-1.80,0.10), Z=1.75, P=0.08>0.05] compared to other exercise [MD=-0.55, 95% CI (-1.16,0.06), Z=1.76, P=0.08>0.05]. In terms of improving low back dysfunction, the Pilates exercise group ODI scores were significantly different compared to other muscle group training [MD=-2.35, 95% CI (-4.06,-0.65), Z=2.71, P=0.007] and medication and physiotherapy [MD=-10.25, 95% CI (-11.24,-9.26), Z=20.34, P<0.00001 ] were significantly different compared to other exercise workouts, QBPDS scores in the Pilates exercise group were not statistically significant compared to other exercise workouts [MD=-1.11, 95% CI (-6.48,4.27), Z=0.40, P=0.69], RMDQ scores in the Pilates exercise group were not statistically significant compared to the usual care and mission group [MD=-1.60, 95% CI (-3.06,-0.15) Z=2.16, P=0.03] were significantly different. Conclusion Pilates exercises improve low back dysfunction in patients with non-specific low back pain. Pilates exercises are more effective than other muscle group training in relieving low back pain, while there is no significant difference compared to other exercise exercises, and drug and physical therapy, as well as conventional care and missionary therapy.