Pigmented Bowen's Disease Research Articles

Dark Plaques in Nether Regions

UNDER the title Multicentric Pigmented Bowen's Disease of the Groin, Lloyd1reported a case of squamous cell carcinoma in situ in a 22-year-old Yemenite man. The eruption consisted of jet-black plaques on either side of the scrotum and inner aspects of the thighs. The plaques were sharply demarcated, with the larger lesions coalescing and showing a velvety surface. Matta and Kaidbey2described a 32-year-old Lebanese man who had two brownish-black pruritic plaques of the prepuce. Both patients had biopsy specimens that showed Bowen disease, with an increased amount of epidermal and dermal pigment. I report two cases of similar multicentric eruptions in female patients. Report of Cases Case 1.— A 37-year-old white woman had a leukoplakic area of the vulva. Bowen disease was diagnosed on biopsy. A radical vulvectomy and an inguinal and iliac lymphadenectomy were performed. The pathologic report was carcinoma in situ without invasion and without

Dark plaques in nether regions. A sign of carcinoma in situ

UNDER the title "Multicentric Pigmented Bowen's Disease of the Groin," Lloyd¹reported a case of squamous cell carcinoma in situ in a 22-year-old Yemenite man. The eruption consisted of jet-black plaques on either side of the scrotum and inner aspects of the thighs. The plaques were sharply demarcated, with the larger lesions coalescing and showing a velvety surface. Matta and Kaidbey²described a 32-year-old Lebanese man who had two brownish-black pruritic plaques of the prepuce. Both patients had biopsy specimens that showed Bowen disease, with an increased amount of epidermal and dermal pigment. I report two cases of similar multicentric eruptions in female patients. <h3>Report of Cases</h3><h3>Case 1.—</h3> A 37-year-old white woman had a leukoplakic area of the vulva. Bowen disease was diagnosed on biopsy. A radical vulvectomy and an inguinal and iliac lymphadenectomy were performed. The pathologic report was carcinoma in situ without invasion and without

Multicentric Pigmented Bowen's Disease

Multicentric Pigmented Bowen's Disease

PIGMENTED BOWEN'S DISEASE

To the Editor.— Recently, Lloyd recorded the first case of multicentric pigmented Bowen's disease of the groin. 1 To underline this distinctive variant of Bowen's disease, we would like to describe a similar patient in whom the clinical diagnosis was missed. Report of a Case A 34-year-old Lebanese man presented with two brownish-black pruritic plaques over the prepuce of 2 years' duration. The plaques were roughly circular, each measuring about 5 mm in diameter. They were slightly elevated and sharply demarcated, having a smooth velvety surface. The lesions had remained stationary. The clinical diagnoses considered were seborrheic keratosis and lichen planus. There was no response to topically or intralesionally administered steroids. A biopsy showed diffuse epidermal hyperplasia. The prickle cells appeared disorganized with foci of atypical changes consisting of loss of polarity, hyperchromasia, and dyskeratoses Many mitotic figures were seen (Figure). The basal cell layer was intact but was heavily

Multicentric pigmented Bowen's disease of the groin

Multicentric pigmented Bowen's disease of the groin

Multicentric Pigmented Bowen's Disease of the Groin

An unusual case of squamous cell carcinoma in situ is reported in a 22-year-old Yeminite man. It was characterized by extensive pigmentation, bilateral groin involvement, and multicentric origin.