Picture Naming Test Research Articles

Protocol for Cerebellar Stimulation for Aphasia Rehabilitation (CeSAR): A randomized, double-blind, sham-controlled trial.

In this randomized, double-blind, sham-controlled trial of Cerebellar Stimulation for Aphasia Rehabilitation (CeSAR), we will determine the effectiveness of cathodal tDCS (transcranial direct current stimulation) to the right cerebellum for the treatment of chronic aphasia (>6 months post stroke). We will test the hypothesis that cerebellar tDCS in combination with an evidenced-based anomia treatment (semantic feature analysis, SFA) will be associated with greater improvement in naming untrained pictures (as measured by the change in Philadelphia Picture Naming Test), 1-week post-treatment, compared to sham plus SFA. We will also evaluate the effects of cerebellar tDCS on naming trained items as well as the effects on functional communication, content, efficiency, and word-retrieval of picture description, and quality of life. Finally, we will identify imaging and linguistic biomarkers to determine the characteristics of stroke patients that benefit from cerebellar tDCS and SFA treatment. We expect to enroll 60 participants over five years. Participants will receive 15, 25-minute sessions of cerebellar tDCS (3-5 sessions per week) or sham tDCS combined with 1 hour of SFA treatment. Participants will be evaluated prior to the start of treatment, one-week post-treatment, 1-, 3-, and 6-months post-treatment on primary and secondary outcome variables. The long-term aim of this study is to provide the basis for a Phase III randomized controlled trial of cerebellar tDCS vs sham with concurrent language therapy for treatment of chronic aphasia. Trial registration: The trial is registered with ClinicalTrials.gov NCT05093673.

Mental health problems raise the odds of cognitive impairment in COVID-19 survivors.

COVID-19 survivors around the globe are suffering from mental health issues. While mental health problems can be an early warning sign of dementia, they may also increase the chances of developing the disease. In this study, we examined the mental health of COVID-19 survivors and mapped its associations with cognitive and demographic variables. COVID-19 survivors listed in the databases of three tertiary care hospitals in Kolkata were contacted sequentially. 376 willing patients were interviewed over the telephone. 99 COVID-19 patients and 31 matched controls participated in the in-person interviews that were arranged for a more detailed investigation. The participants were administered standardized tests that are widely used for the assessment of cognitive functioning and mental health status. 64.89% of COVID-19 survivors reported a deterioration in physical functioning. 44.95% reported a decline in mental health, whereas 41.49% reported a drop in cognitive performance. Detailed investigations revealed that they had an increased risk of having depression, anxiety, and poor sleep quality by 91%, 68%, and 140%, respectively. 6.1% of the patients had mild cognitive impairment, and 4% had dementia. COVID-19 patients who had depression and anxiety were 8.6 and 19.4 times more likely to have cognitive decline, respectively. Compared to the matched controls, COVID-19 patients had greater depression (p<.001), anxiety (p<.001), stress (p =.003), and insomnia (p <.001). They also scored significantly lower on Addenbrooke's Cognitive Examination-III (p =.009) and Picture Naming Test (p =.005) and took significantly longer to complete Trail Making Test-A (p =.002). COVID-19 survivors in this study had major mental health issues even one year after contracting the virus. They had significant cognitive deficits that might progress into dementia. Strict monitoring and systematic treatment plans should be implemented as soon as possible.

Establishing and evaluating the gradient of item naming difficulty in post-stroke aphasia and semantic dementia

Anomia is a common consequence following brain damage and a central symptom in semantic dementia (SD) and post-stroke aphasia (PSA), for instance. Picture naming tests are often used in clinical assessments and experience suggests that items vary systematically in their difficulty. Despite clinical intuitions and theoretical accounts, however, the existence and determinants of such a naming difficulty gradient remain to be empirically established and evaluated. Seizing the unique opportunity of two large-scale datasets of semantic dementia and post-stroke aphasia patients assessed with the same picture naming test, we applied an Item Response Theory (IRT) approach and we (a) established that an item naming difficulty gradient exists, which (b) partly differs between patient groups, and is (c) related in part to a limited number of psycholinguistic properties - frequency and familiarity for SD, frequency and word length for PSA. Our findings offer exciting future avenues for new, adaptive, time-efficient, and patient-tailored approaches to naming assessment and therapy.

Assessing Relative Linguistic Impairment With Model-Based Item Selection.

A picture naming test is presented that reveals impairment to specific mechanisms involved in the naming process, using accuracy scores on curated item sets. A series of psychometric validation experiments are reported. Using a computational model that enables estimation of item difficulty at the lexical and sublexical stages of word retrieval, two complimentary sets of items were constructed that challenge the respective psycholinguistic levels of representation. The difference in accuracy between these item sets yields the relative linguistic impairment (RLI) score. In a cohort of 91 people with chronic left-hemisphere stroke who enrolled in a clinical trial for anomia, we assessed psychometric properties of the RLI score and then used the new scale to make predictions about other language behaviors, lesion distributions, and functional activation during naming. RLI scores had adequate psychometric properties for clinical significance. RLI scores contained predictive information about spontaneous speech fluency, over and above accuracy. A dissociation was observed between performance on the RLI item sets and performance on the subtests of an independent language battery. Sublexical RLI was significantly associated with apraxia of speech and with lesions encompassing perisylvian regions, while lexical RLI was associated with lesions to deep white matter. The RLI construct was reflected in functional brain activity during naming, independent of overall accuracy, with a respective shift of activation between dorsal and ventral networks responsible for different aspects of word retrieval. The RLI assessment satisfies the psychometric requirements to serve as a useful clinical measure.

Awake Craniotomy for Astrocytoma in the Left Frontal Lobe Using Augmented Reality Superimposing Tumor and White Matter Tracts: 2-Dimensional Operative Video.

Augmented reality (AR) is expected to serve as an assistive intraoperative technology in neurosurgery.1 Awake craniotomy (AC) for gliomas benefits the extent of resection, survival, and postoperative neurofunctional outcomes.2 In AC, it is critical to understand the cortical and subcortical anatomy.3 We describe the use of AR superimposing tumor and deep white matter tracts in AC. A 29-year-old right-handed woman presented to a local hospital after an episode of generalized convulsions. MRI of the head revealed a widely spreading tumor in the left middle frontal gyrus. After a left frontal craniotomy while the patient was asleep, AR was used to indicate the tumor boundary with subcortical fibers including the corticospinal tract, inferior fronto-occipital fasciculus, and cingulate fasciculus. We performed AR-assisted removal of the tumor on the surface of the middle frontal gyrus. On subcortical stimulation (SCS) of the frontal aslant tract and inferior fronto-occipital fasciculus, the patient stopped naming objects in the picture-naming test, while SCS of the left cingulate gyrus caused the patient to mistake colors in the Stroop test. The subcortical fibers identified by AR coincided with the sites of symptom elicitation by SCS. We eventually removed a large part of the tumor. Postoperative MRI confirmed 96.2% resection. The patient was discharged without any new neurological deficits. AC with AR is useful for resection of gliomas in the dominant hemisphere. The patient consented to the procedure and to the publication of her image. The ethics committee of our hospital does not require approval for case reports.

Evaluation of the Oxford cognitive screen Indonesian version (OCS-Ina) for assessing cognitive function disorders: validation and reliability study

Background and objectives. The Oxford Cognitive Screen (OCS) is a valuable tool for assessing cognitive function, particularly in the context of aphasia and neglect. This study aims to assess the validity and reliability of the Indonesian version of OCS (OCS-INA), which has been adapted and translated following WHO guidelines. Materials and methods. The adaptation and translation process of OCS, in accordance with WHO guidelines, preceded the validity and reliability testing of OCS-INA. The study included participants aged 18 years and above with normal cognitive function, as assessed by the Moca-INA. Data collection took place in social institutions and healthcare facilities that met the specified inclusion criteria. Results. Among the 104 participants meeting the inclusion criteria, a majority were male (51.92%), with ages ranging from 20 to 87 years, and the highest age group being above 60 years (60%). Most participants had a high school education level (35.58%) and were not employed (62.5%). Validity testing, using the Spearman correlation coefficient formula, revealed that the majority of domains had calculated correlation coefficients (r values) exceeding the table values (0.1927). In terms of reliability, the kappa p statistic indicated very good agreement for six examination tasks: semantic (0.874), orientation (0.842), verbal memory (0.822), episodic memory (0.870), and visual field test (1.000). Good agreement scores were obtained for the picture naming test (0.774), sentence reading (0.726), and calculation (0.774). Conclusions. In conclusion, OCS-INA demonstrates both validity and reliability as a screening tool for cognitive impairment. It serves as a valuable complement to existing instruments used for similar purposes.

Picture naming test through the prism of cognitive neuroscience and linguistics: adapting the test for cerebellar tumor survivors-or pouring new wine in old sacks?

A picture naming test (PNT) has long been regarded as an integral part of neuropsychological assessment. In current research and clinical practice, it serves a variety of purposes. PNTs are used to assess the severity of speech impairment in aphasia, monitor possible cognitive decline in aging patients with or without age-related neurodegenerative disorders, track language development in children and map eloquent brain areas to be spared during surgery. In research settings, picture naming tests provide an insight into the process of lexical retrieval in monolingual and bilingual speakers. However, while numerous advances have occurred in linguistics and neuroscience since the classic, most widespread PNTs were developed, few of them have found their way into test design. Consequently, despite the popularity of PNTs in clinical and research practice, their relevance and objectivity remain questionable. The present study provides an overview of literature where relevant criticisms and concerns have been expressed over the recent decades. It aims to determine whether there is a significant gap between conventional test design and the current understanding of the mechanisms underlying lexical retrieval by focusing on the parameters that have been experimentally proven to influence picture naming. We discuss here the implications of these findings for improving and facilitating test design within the picture naming paradigm. Subsequently, we highlight the importance of designing specialized tests with a particular target group in mind, so that test variables could be selected for cerebellar tumor survivors.

Production of nouns and adjectives of children with cochlear implants and of children with typical hearing

This analytical cross-sectional study aimed to investigate the production of nouns and adjectives in 62 children between the ages 5 and 7, with 31 children having Cochlear Implants (CIs) and 31 children having Typical Hearing (TH). The study compaired their performance in a picture naming test of nouns and adjectives. Poisson regression models were fitted to compare the responses of both groups of children, and intra-subject differences between responses to the noun and adjective naming tasks were also analyzed. The results showed that both groups of children produced the same number of non-responses of nouns and of adjectives and a higher number of correct productions of nouns than of adjectives. However, children with CIs produced more errors when naming adjectives than when naming nouns, while this difference is not observed in children with TH. The comparative analysis between both groups of children indicates that children with CIs produced a higher proportion of non-responses when naming nouns, but the same proportion as children with TH when naming adjectives. Children with CIs also produced fewer correct nouns and adjectives and more errors than children with TH. Vocabulary expansion and repair of production errors in children with CIs should be targeted by speech-language pathologists in intervention programs.

Picture naming test: Linguistic challenges of the method and ways to solve them

The paper considers benefits and drawbacks of the Picture Naming Test (PNT) as a diagnostic method suggesting the ways to improve its diagnostic and research validity. Although this test is popular in both national and international neuropsychological assessment and research practice, its use is largely due to tradition and practical convenience. However, theoretical underpinnings for its effectiveness are not sufficiently represented in the pertinent literature, which determines the relevance of the study. The major objective of the paper is to consider the PNT as a research technique from the point of view of psycholinguistics, cognitive science, and corpus linguistics and to propose integrated approaches for the further development of these tests. The material comprises picture naming tests developed for the Russian and English languages. The study sets the following aims: 1) to define the main features of PNT and the principles of its application viewed from a historical perspective; 2) to identify the theoretical foundations (linguistic and neuropsychological) for its use as a diagnostic tool; 3) to highlight the problematic aspects of the method; 4) to suggest possible ways to eliminate them. To accomplish these tasks, various methods of corpus linguistics are applied throughout the article. The historical outline of PNT development suggests that the current design might stem from earlier contexts of use. A review of existing models of lexical access provides a theoretical basis for the test in its current form and suggests possible avenues for its development grounded in experimental research, advances in linguistics and big data analysis. A separate section of the article presents critique of the most popular tests. Finally, the analysis of the existing English and Russian tests through the corpus-based methodology clearly demonstrates the need for more detailed norming and stimuli selection. By way of conclusion the authors outline the principles of designing Picture Naming Tests for specific purposes and put forward a step-by-step algorithm that enables careful selection of the necessary indicators and parameters.

Preoperative word-finding difficulties in children with posterior fossa tumours: a European cross-sectional study.

Posterior fossa tumour surgery in children entails a high risk for severe speech and language impairments, but few studies have investigated the effect of the tumour on language prior to surgery. The current crosslinguistic study addresses this gap. We investigated the prevalence of preoperative word-finding difficulties, examined associations with medical and demographic characteristics, and analysed lexical errors. We included 148 children aged 5-17years with a posterior fossa tumour. Word-finding ability was assessed by means of a picture-naming test, Wordrace, and difficulties in accuracy and speed were identified by cut-off values. A norm-based subanalysis evaluated performance in a Swedish subsample. We compared the demographic and medical characteristics of children with slow, inaccurate, or combined slow and inaccurate word finding to the characteristics of children without word-finding difficulties and conducted a lexical error analysis. Thirty-seven percent (n = 55) presented with slow word finding, 24% (n = 35) with inaccurate word finding, and 16% (n = 23) with both slow and inaccurate word finding. Children with posterior fossa tumours were twice as slow as children in the norming sample. Right-hemisphere and brainstem location posed a higher risk for preoperative word-finding difficulties, relative to left-hemisphere location, and difficulties were more prevalent in boys than in girls. The most frequent errors were lack of response and semantically related sideordinated words. Word-finding difficulties are frequent in children with posterior fossa tumours, especially in boys and in children with right-hemisphere and brainstem tumours. Errors resemble those observed in typical development and children with word-finding difficulties.

Phonological development in first language Laki-speaking children aged 3 to 5 years: A pilot study

Purpose To date there are no studies of speech sound acquisition in Laki, a language spoken in western regions of Iran. Thus, we set out a pilot study to investigate the speech development of 56 first language Laki-speaking children (aged 3–5 years). Method Single words were elicited through a picture naming test specifically developed for this study. After recording and transcribing of speech samples, percentage of consonants correct (PCC), percentage of vowels correct (PVC), and proportion of whole word proximity (PWP) were documented in four age groups (36–41, 42–47, 48–53, and 54–59 months) and both genders. Children’s phonetic inventories and consonant and vowel accuracy were also described. Result All the sounds were considered as emerging by 53 months of age. For speech sound accuracy, all the speech sounds except /ɢ, z, ŋ, ʒ/ were mastered by 5 years. The effect of age on PCC values was significant. Also, age groups showed significant differences for PWP but were not significant for PVC. Boys and girls did not differ for PCC, PVC, and PWP values. Conclusion From a theoretical perspective, findings contribute to theories about phonological acquisition in general and will enable crosslinguistic comparisons. From an applied standpoint, language-specific characteristics are identified, which are much needed for clinical practice with Laki-speaking children.

The MINT Sprint 2.0: A picture naming test for detection of naming impairments in Alzheimer's disease and in preclinical AD.

Evidence on the onset of naming deficits in Alzheimer's disease (AD) is mixed. Some studies showed an early decline, but others did not. The present study introduces evidence from a novel naming test. Cognitively normal (n=138), mild cognitive impairment (MCI; n=21), and Alzheimer's disease (AD; n=31) groups completed an expanded Multilingual Naming Test with a time-pressured administration procedure (MINT Sprint 2.0). Cerebrospinal fluid biomarkers classified participants as true controls (n=61) or preclinical AD (n=26). Total correct MINT Sprint 2.0 scores exhibited good sensitivity and specificity (>0.85) for discriminating true controls from cognitively impaired (MCI/AD) groups and showed significant differences between true controls and preclinical AD groups. Time measurement did not improve classification, but percent resolved scores exhibited promise as an independent AD marker. Naming deficits can be detected in the earliest stages of AD with tests and procedures designed for this purpose.

Comparing two picture naming tasks in primary progressive aphasia: Insights from behavioural and neural results

Picture naming tests are widely used to evaluate language impairments in neurodegenerative diseases, especially in Primary Progressive Aphasia (PPA). The available tests differ for many factors affecting the performance, e.g. format of stimuli and their psycholinguistic properties. We aim to identify the most appropriate naming test to be used on PPA according to the clinical and research demands. We investigated the behavioural characteristics, i.e. proportion of correct responses and error type, and their neural correlates in two Italian naming tests, CaGi naming (CaGi) and naming subtest of the Screening for Aphasia in NeuroDegeneration battery (SAND), administered to 52 PPA patients who underwent an FDG-PET scan. We analysed the effectiveness of the tests in distinguishing PPA versus controls and among PPA variants, considering the psycholinguistic variables affecting performance. We explored the brain metabolic correlates of behavioural performance in the tests. SAND, differently from CaGi, has time limits for the response and its items are less frequent and acquired later. SAND and CaGi differed in terms of number of correct responses and error profile, suggesting a higher difficulty to name SAND items compared to CaGi. Semantic errors predominated in CaGi, while anomic and semantic errors were equally frequent in SAND. Both tests distinguished PPA from controls, but SAND outperformed CaGi in discriminating among PPA variants. FDG-PET imaging revealed a shared metabolic involvement of temporal areas associated with lexico-semantic processing, encompassing anterior fusiform, temporal pole, and extending to posterior fusiform in sv-PPA. Concluding, a picture naming test with response time limit and items which are less frequent and acquired later in life, as SAND, may be effective at highlighting subtle distinctions between PPA variants, improving the diagnosis. Conversely, a naming test without time limit for the response, as CaGi, may be useful for a better characterization of the nature of the naming impairment at the behavioural level, eliciting more naming errors than anomia, possibly helping in the development of rehabilitation protocols.

Articulation Test for Bahdini Kurdish Preschool Children

ABSTRACT &#x0D; Articulation tests record and analyze children’s speech and they are used to determine which sounds children can or cannot say or if the speech errors the children produce are developmentally appropriate or they are delayed. The aim of this study was to develop an articulation test for Bahdini Kurdish preschool children. For this purpose, a picture-naming test was designed to elicit spontaneous single-word responses representing 26 consonants in initial, medial and final positions and 8 vowels in medial positions. Seven experts were asked to review the test and complete a questionnaire. Then, it was presented to 65 normal Bahdini Kurdish speaking children. They were 38 males and 27 females from three different age groups: 3, 4, and 5 years old. The children’s responses were recorded and then scored for each correct utterance and picture identification. The results show that there are no significant differences among the experts’ responses which reflect their approval for the test to be a valid tool for collecting the phonetic inventory of the children. There is a significant and high correlation between correct word utterances and picture identification which prove the content validity of the test. Finally, there are no significant differences between males and females which indicates that the test is suitable for both genders, while significant differences were found among age groups in which old children performed better than younger ones. Thus, the test is a valid and a reliable tool that can be applied to collect the phonetic inventory of Bahdini Kurdish speaking children.

Refining Semantic Similarity of Paraphasias Using a Contextual Language Model.

ParAlg (Paraphasia Algorithms) is a software that automatically categorizes a person with aphasia's naming error (paraphasia) in relation to its intended target on a picture-naming test. These classifications (based on lexicality as well as semantic, phonological, and morphological similarity to the target) are important for characterizing an individual's word-finding deficits or anomia. In this study, we applied a modern language model called BERT (Bidirectional Encoder Representations from Transformers) as a semantic classifier and evaluated its performance against ParAlg's original word2vec model. We used a set of 11,999 paraphasias produced during the Philadelphia Naming Test. We trained ParAlg with word2vec or BERT and compared their performance to humans. Finally, we evaluated BERT's performance in terms of word-sense selection and conducted an item-level discrepancy analysis to identify which aspects of semantic similarity are most challenging to classify. Compared with word2vec, BERT qualitatively reduced word-sense issues and quantitatively reduced semantic classification errors by almost half. A large percentage of errors were attributable to semantic ambiguity. Of the possible semantic similarity subtypes, responses that were associated with or category coordinates of the intended target were most likely to be misclassified by both models and humans alike. BERT outperforms word2vec as a semantic classifier, partially due to its superior handling of polysemy. This work is an important step for further establishing ParAlg as an accurate assessment tool.

Outcomes from a pilot dose comparison study of naming therapy in aphasia

ABSTRACT Background People with aphasia vary considerably in response to aphasia treatments. Treatment dose is likely to be an important factor in understanding treatment response variability and optimising aphasia recovery; however, there is limited empirical evidence to guide dose prescription in post-stroke aphasia rehabilitation. In the present study, we used a novel approach to personalise dose prescription and explored the effect of dose on treatment response in chronic post-stroke aphasia. Aims Examine the effect of providing personalised doses of a cued picture naming treatment (Kendall et al., 2014) on acquisition and maintenance of picture naming outcomes. Method This pilot study used a multiple-baselines design with follow-up at 4- and 12-weeks with replication across four people with chronic post-stroke anomia. Prior to treatment, a comprehensive battery of cognitive and language tests was completed. Participants then undertook a period of cued picture naming treatment (45-minute sessions, five days per week for three weeks) totalling 15 sessions (11.25 hours). Participants were allocated four picture sets – one each for three treated conditions (low dose, moderate dose, and high dose) and one for an untreated control set. The number of naming opportunities provided per dose condition was calibrated against individuals’ pre-treatment picture naming accuracy and speed. Generalised linear mixed effects models were used to evaluate learning effects during treatment, maintenance of these effects, and dose-response relationships. Outcomes Participants received 99% of prescribed treatment doses (i.e., number of naming opportunities provided over the course of treatment). As anticipated, individual treatment responses varied substantially. Three participants demonstrated significantly improved picture naming accuracy on probed items during treatment, with varying response profiles by participant and dose. All participants were able to name more pictures accurately on a bespoke 298-item object picture naming test following treatment. However, no participant demonstrated significant pre-post treatment gains relative to untreated items, although one person demonstrated improved naming four weeks after treatment for items treated under the high dose condition. Dose-response relationships amongst these participants exhibited a greater number of significant results on naming probes in the high dose condition, possibly suggesting superiority of the high dose condition over lower doses of cued picture naming treatment. Conclusion Modest treatment effects and variable dose-response relationships were observed. We explore the role of dose, cognitive factors such as self-monitoring abilities, and linguistic factors such as underlying lexical-semantic and phonological processing that may have influenced treatment response in these participants. Avenues for future research are identified.

Validation of and Normative Data of the DVAQ-30, a New Video-Naming Test for Assessing Verb Anomia.

Anomia is usually assessed using picture-naming tests. While many tests evaluate anomia for nouns, very few tests have been specifically designed for verb anomia. This article presents the DVAQ-30, a new naming test for detecting verb anomia in adults and elderly people. The article describes three studies. Study 1 focused on the DVAQ-30 development phase. In Study 2, healthy participants and individuals with post-stroke aphasia, mild cognitive impairment, Alzheimer's disease, or primary progressive aphasia were assessed using the DVAQ-30 to establish its convergent and discriminant validity, test-retest reliability, and internal consistency. In Study 3, a group of adults and elderly Quebec French-speaking adults were assessed to obtain normative data. The DVAQ-30 had good convergent validity and distinguished the performance of healthy participants from that of participants with pathological conditions. The test also had good internal consistency, and the test-retest analysis showed that the scores had good temporal stability. Furthermore, normative data were collected on the performance of 244 participants aged 50years old and over. The DVAQ-30 fills an important gap and has the potential to help clinicians and researchers better detect verb anomia associated with pathological aging and post-stroke aphasia.

Reliability of data on percent consonants correct and its associated quality indicator in the Swedish cleft lip and palate registry.

Data in national health care quality registries must be valid and reliable in order to enable open comparisons of results. To assess the reliability of data on percent consonants correct (PCC) and its associated quality indicator ≥86% correct consonants in the Swedish quality registry for patients born with cleft lip and palate (CLP) registry. Six independent speech-language pathologists re-assessed the audio recordings of 96 five-year-olds with PCC data in the CLP registry. Target consonants of a single-word picture-naming test were phonetically transcribed, and PCC was calculated. The reliability of PCC data was assessed with the intraclass correlation coefficient (ICC). The reliability of the quality indicator ≥86% correct consonants was assessed with point-by-point percentage agreement and Cohen's kappa. Intra- and inter-judge agreement for PCC was excellent with ICCs above 0.9, and so was the agreement of data from the CLP registry and the six judges' re-assessments. The percentage agreement between all judges and the CLP registry for the quality indicator ≥86% correct consonants was poor (67%). However, in 88% of the cases, results from four judges and the CLP registry agreed, corresponding to good agreement. The mean of all kappa values for six judges and the CLP registry corresponded to good agreement (0.72). The results indicate the PCC data in the CLP registry and the quality indicator ≥86% correct consonants to be reliable. When differences in outcome between treatment centres are detected, the raw data collected should always be re-examined before drawing definitive conclusions.

Picture-naming test for a linguistically diverse population with cognitive impairment and dementia.

Picture-naming tests (PNTs) evaluate linguistic impairment in dementia due to semantic memory impairment, impaired lexical retrieval or perceptual deficits. They also assess the decline in naming impairment at various stages of dementia and mild cognitive impairment (MCI) that occurs due to progressive cognitive impairment. With the increasing numbers of people with dementia globally, it is necessary to have validated naming tests and norms that are culturally and linguistically appropriate. In this cross-sectional study we harmonized a set of 30 images applicable to the Indian context across five languages and investigated the picture-naming performance in patients with MCI and dementia. A multidisciplinary expert group formed by the Indian Council of Medical Research (ICMR) collaborated towards developing and adapting a picture naming test (PNT) known as the ICMR-PNT in five Indian languages: Hindi, Bengali, Telugu, Kannada and Malayalam. Based on cross-cultural adaptation guidelines and item-wise factor analysis and correlations established separately across five languages, the final version of the ICMR-PNT test was developed. A total of 368 controls, 123 dementia and 128 MCI patients were recruited for the study. Psychometric properties of the adapted version of the ICMR-PNT were examined, and sensitivity and specificity were examined. The ICMR-PNT scores in all languages combined were higher in controls compared with patients with dementia and MCI (F2, 615 = 139.85; p < 0.001). Furthermore, PNT scores for MCI was higher in comparison with patients with dementia in all languages combined (p < 0.001). The area under the curve across the five languages ranged from 0.81 to 1.00 for detecting dementia. There was a negative correlation between Clinical Dementia Rating (CDR) and ICMR-PNT scores and a positive correlation between Addenbrooke's Cognitive Examination-III (ACE-III) and ICMR-PNT scores in control and patient groups. The ICMR-PNT was developed by following cross-cultural adaptation guidelines and establishing correlations using item-wise factor analysis across five languages. This adapted PNT was found to be a reliable tool when assessing naming abilities effectively in mild to moderate dementia in a linguistically diverse context. What is already known on this subject Picture-naming evaluates language impairment linked to naming difficulties due to semantic memory, lexical retrieval or perceptual disturbances. As a result, picture naming tests (PNTs) play an important role in the diagnosis of dementia. In a heterogeneous population such as India, there is a need for a common PNT that can be used across the wide range of languages. What this study adds to existing knowledge PNTs such as the Boston Naming Test (BNT) were developed for the educated, mostly English-speaking, Western populations and are not appropriate for use in an Indian context. To overcome this challenge, a PNTwas harmonized in five Indian languages (Hindi, Bengali, Telugu, Kannada and Malayalam) and we report the patterns of naming difficulty in patients with MCI and dementia. The ICMR-PNT demonstrated good diagnostic accuracy when distinguishing patients with mild to moderate dementia from cognitively normal individuals. What are the potential or actual clinical implications of this work? With the growing number of persons suffering from Alzheimer's disease and other forms of dementia around the world, its critical to have culturally and linguistically relevant naming tests and diagnosis. This validated ICMR-PNT can be used widely as a clinical tool to diagnose dementia and harmonize research efforts across diverse populations.

Comparison of language and narrative features of individuals among amnestic mild cognitive impairment and healthy adults

AbstractBackgroundMild Cognitive Impairment (MCI) is a stage between normal aging and dementia. Even though individuals have some decline in cognition due to normal aging, preserved daily life functioning skills is the main distinction between dementia and MCI. Individuals with MCI experience mild impairments in memory, language and judgement.MCI is classified in two subtypes: one is amnestic MCI which is characterized by memory impairment, the other one is non‐amnestic MCI in which other cognitive domains are impaired. Individuals with amnestic MCI (aMCI) are at increased risk of developing Alzheimer disease (AD). The purpose of this study is to determine the language and narration skills of individuals with aMCI and to compare their scores with healthy participants.MethodFor this purpose, the Test Your Memory – Turkish Version (TYM‐TR), the Turkish Picture Naming Test (T‐RAT), the Aphasia Language Assessment Test (ADD) Repetition Subtest, the Turkish Nonword Repetition Test (TAST) were administered to 60 participants between the ages of 60‐85, 30 with aMCI and 30 healthy individuals. Pyramid and Palm Trees Test (PPTT) and the Multilingual Assessment Instrument for Narratives (MAIN‐TR) Dog Story Retelling tasks were also administered.ResultAfter the distribution of the data was examined, those with normal distribution were compared between the groups with independent samples T test and the data that did not show a normal distribution were calculated using non‐parametric Mann Whitney‐U. As a result of the statistical analysis, it was determined that nonword repetition differed significantly between the groups. As for macrostructures, it was determined that there was a difference between the groups in terms of story structure and comprehension. As for the other parameters, even though the average of healthy individuals was higher, no significant difference was found between the groups.ConclusionThis study is the first on the language and narrative skills of the participants with aMCI in Turkish, and it is thought that it will shed light on the language skills of individuals with aMCI during the neurodegeneration process. Determining the changes in language skills is very important in setting goals for Language and Speech Therapy.