Abstract Due to the specificity of neutral beam injection (NBI) system, the control of its actual physical system is achieved by the integrated control system (ICS). The current NBI ICS adopts a distributed design structure to balance the system load, which is also the mainstream system design and architecture model of ICS around the world. However, from a practical point of view, the distributed system architecture is not perfect. In the long run, upgrading the system intelligence and automation capabilities is an inevitable choice for the future, so it is necessary to explore ways to transform and upgrade the ICS. At present, Internet of Things (IoT), as an important part of the new generation information technology, can realize the control of everything through data exchange. This is because on the one hand, IoT has wide compatibility and powerful scenario-based capabilities, it not only has the advantages and characteristics of distributed design, but also can pull the NBI subsystems into the same level scenario and lay the foundation for the further construction of digital NBI; on the other hand, the intervention of artificial intelligence makes IoT have some new typical characteristics such as intelligent sensing, ubiquitous connectivity, precise control, digital modeling, real-time analysis and iterative optimization, which is enough to pull the current NBI ICS into a new intelligent control era. Finally, it is worth mentioning that due to its inherent design structure and functional characteristics, ICS tends to be broadly generic, so it is not exclusively used for NBI operation in nuclear fusion, and it can provide some insight into other application areas.