Characterization Of Physical Properties Research Articles

Study on the Characterization of Physical, Mechanical, and Creep Properties of Masson Pine and Chinese Fir Wood Flour-Reinforced High-Density Polyethylene Composites

Improving the physical, mechanical, and creep properties of wood fiber-reinforced polymer composites is crucial for broadening their application prospect. In this research, seven types of high-density polyethylene (HDPE) composites reinforced with different mass ratios of Masson pine (Pinus massoniana Lamb.) and Chinese fir [Cunninghamia lanceolata (Lamb.) Hook.] were prepared by a two-step extrusion molding method. The mass ratios of the two fibers were 60:0, 50:10, 40:20, 30:30, 20:40, 10:50, and 0:60, respectively. The surface color, density, dimension stability, bending, tensile, impact properties, dynamic mechanical properties, and 24 h creep properties at a 10% stress level of the seven composites were investigated. Additionally, the Rule of Mixtures (ROM), the Inverse Rule of Mixtures (IROM), the Hirsch models, and the improved model were employed to simulate the mechanical properties, while the Findley index model, the two-parameter index model, and the modified ExpAssoc model were employed to simulate the creep performance of the composites. This study revealed that as the proportion of Chinese fir wood flour increased, the mechanical properties of the composites gradually improved, the storage modulus showed an increasing trend, while the loss modulus decreased, and the overall creep strain of the composites increased. Among the various models, the modified model simulated the mechanical properties of the composites the best, while the modified ExpAssoc model simulated the creep behavior most effectively.

Deterioration characterization of sandstone physical and mechanical properties under mining and water action

Mining geological disasters occur frequently in Guizhou, with mine mining and rainfall-induced avalanche geological disasters mainly, the investigation concluded that the hard rock of the overlying slide body is mostly sandstone, and it is crucial to study the physical and mechanical properties of sandstone under the action of mine mining (hereinafter referred to as the action of mining) and water action. The paper analyzes the deterioration characteristics of sandstone hydrophysical and mechanical properties under the action of mining and water. The main research results are as follows: (1) The water absorption rate of sandstone increased by 0.056% under the action of mining, the water absorption rate of sandstone increased with a good exponential relationship under the action of dry and wet cycles, the swelling rate of sandstone increased by 0.3% under the action of mining, and the index of disintegration resistance decreased by 0.3% in 5 cycles; (2) The damage rate of uniaxial compressive strength of sandstone after being subjected to mining was 6.367%. The total deterioration rate increases with the number of wet and dry cycles, the stage deterioration rate and the average stage deterioration rate first decrease and then increase, and the degree of fragmentation gradually increases; (3) According to the microscopic test results, the microstructural evolution of “mining cracking → water adsorption → water–rock interaction” model was established.

Characterization of Physical, Morphological and Mechanical Properties of Poly-Lactic Acid/Graphene (PLA/GNPs) Biopolymer Composites using Fused Deposition Modelling

A hybrid biopolymer composite consisting of Poly-Lactic Acid/Graphene Nanoplatelets (PLA/GNPs) was formulated using double planetary mixer (DPM) and processed into granules and utilized as the feedstock for additive manufacturing (AM) of structures using the Fused Deposition Modelling (FDM) technique. The study aimed to investigate the influence of different weight percentages (1%, 3% and 5%) of graphene nanoplatelets (GNPs) on the physical, morphological and mechanical properties of the printed test samples. Differential Scanning Calorimetry (DSC) revealed the temperature ranges for the glass transition temperature (Tg) and crystallinity temperature (Tc) to be 61–63 °C and 112–140 °C, respectively. Additionally, it was observed that the presence of graphene in the polymer matrix led to a decrease in the melting temperature (Tm), with the sample containing 1 wt% of GNPs displaying the highest melting point. Furthermore, the density of the biopolymer composite increased as the weight percentage of GNPs increased. Microscopic examination of the samples revealed the presence of voids, waves and interlayer gaps in all compositions containing GNPs. These conditions were likely caused by inadequate material preparation and inaccurate printing parameter settings. In terms of mechanical properties, the highest tensile modulus observed was 1.29 GPa with 5 wt% GNPs, the highest flexural modulus was 5.17 GPa with 5 wt% GNPs and the highest compressive modulus was 10.073 GPa with 3 wt% GNPs. These results may be attributed to low homogeneity during the mixing process.

Characterization of Physical and Chemical Properties of Multi-Source Metallurgical Dust and Analysis of Resource Utilization Pathways

Steel metallurgical dust, characterized by a substantial output, minute particle size, and intricate composition, poses a considerable risk of environmental contamination while simultaneously embodying an exceptionally high potential for recycling. To achieve its resource utilization, chemical analysis, particle size analysis, X-ray diffraction (XRD), scanning electron microscopy (SEM), Mössbauer spectroscopy, and water leaching methods were employed to investigate the chemical compositions, particle size distributions, phase compositions, and microscopic morphologies of blast furnace bag dust, sintering dust, converter fine dust, and electric arc furnace dust from steel plants. The results indicate that the four types of dust have extremely fine particle sizes, with the main distribution range of particle size being less than 100 μm. The main constituent element is Fe (19–56%), and it also contains Zn (1.4–33.5%), Pb, K, C, and other valuable elements. Alkali metals in blast furnace bag dust and sintering machine head dust existed mainly in the form of chloride. The zinc phases in sintering machine head dust and converter fine dust were ZnFe2O4, and the zinc phases in blast furnace bag dust were ZnCl2 and ZnFe2O4. Zinc in electric furnace dust was composed of ZnO and ZnFe2O4, accounting for 70.31% and 23.12%, respectively. There are significant differences in the types and contents of valuable elements among various dusts, making it difficult to achieve full-scale recovery through a single process. In view of this, a process of “in-plant recycling of harmless dusts—collaborative treatment of harmful dusts” has been proposed. Based on the characteristics of metallurgical dusts, multiple processes are used for collaborative treatment (using hydrometallurgical and pyrometallurgical methods), which can not only directly recover iron resources from dusts within the plant, but also avoid the waste of valuable elements such as Zn, Pb, K, Na, etc. It is hoped that the above work can provide a reference for steel enterprises to achieve full-scale and high value-added treatment of metallurgical dusts.

Innovative Al6061-gadolinium oxide ods alloys: fabrication and comprehensive characterization of microstructural, physical, mechanical, and radiation shielding properties

Innovative Al6061-gadolinium oxide ods alloys: fabrication and comprehensive characterization of microstructural, physical, mechanical, and radiation shielding properties

Reprocessable flame retardant amino-ester thermoset

Polymeric materials are vital in modern life due to their versatility and cost-effectiveness. Thermosets are highly valued for their exceptional durability, chemical resistance, and mechanical strength. Despite these advantages, challenges such as enhancing fire safety and recyclability persist. Covalent Adaptable Networks (CANs) offer a promising solution, providing a sustainable platform for materials with self-healing and recyclable properties. This study addresses these challenges by developing innovative CANs through Aza-Michael addition and retro-addition chemistry. Amino-ester networks (AE) composed of m-Xylenediamine, and pentaerythritol triacrylate were manufactured while simultaneously incorporating phosphorus-based flame retardant (FR) additives synthesized in situ. A systematic characterization of physical, thermal, flame-retardant, and reprocessability properties was performed for the novel AE. Ten thermomechanical recycling cycles were performed for the AE to demonstrate the robustness of the new material, showing no degradation or changes in its physical, thermal, and flame-retardant properties. The chemistry involved in the recyclability was characterized via Raman Spectroscopy. The thermoset containing 0.7 wt% phosphorus (P) exhibits self-extinguishing behavior, achieving a V-0 rating. Compared to the material without flame retardant additives, the presence of the new in-situ FR (3.6 wt% P) allows for a significant reduction in total heat release (43%) and total smoke release (46%). The new FR molecule was also compared with a similar, previously reported molecule (EDA-bis-TEPT) and showed significantly better flame-retardant properties. Furthermore, the potential of these innovative thermosets was explored for applications such as fire-safe carbon fiber-reinforced composites, indicating a promising direction for developing sustainable and high-performance polymer materials.

Application of seismic inversion constrained geological modeling technology in quantitative characterization of thin reservoirs

Abstract With the gradual deepening of petroleum exploration and development, the scale of reservoir research in oil and gas reservoirs is getting smaller and smaller, and the demand for accuracy is getting higher and higher. During the development of clastic reservoirs in the Tarim Basin, the lithology of reservoir sand bodies changes rapidly and the lateral continuity is poor, so it is difficult to effectively identify the space distribution of sand bodies by relying solely on geological logging data. In this study, combined with the advantages of logging curve for vertical identification of sand bodies and seismic data for horizontal distribution identification of reservoirs, the seismic inversion constrained geological modeling technology is proposed to realize the quantitative characterization of thin reservoir sand bodies in developed oil and gas reservoirs :①Through the analysis of sensitive characteristic curve and the extraction of targeted seismic plane attributes, the feasibility evaluation of inversion in the target area is completed, and the seismic inversion results of thin reservoirs are generated. ②Based on the results of seismic inversion simulation, a high-precision 3D lithofacies geological model is constructed by analyzing the applicability of stochastic modeling method. ③ Combined with geological cognition, the physical property characterization of 3D lithofacies geological model is realized by physical property truncated simulation method, and the spatial distribution pattern of effective sand bodies is depicted. Through the application of this method in the study area A, the problem of certain deviation between reservoir inversion driven by conventional frame model and geological cognition is solved. While the spatial recognition ability of sand bodies is further improved, the quantitative characterization of thin reservoir physical properties is realized, which provides effective technical support for the subsequent development of oil and gas reservoirs.

Preface

Materials are not only the basic elements of people’s daily life, but also indispensable components in high-tech fields such as energy, information, and advanced manufacturing. The unique and versatile characteristics of advanced materials make them a highly desirable group of candidate materials for various engineering applications. A thorough and comprehensive analysis of the challenges associated with advanced materials can pave the way for their cost-effective applications. In this context, the 2024 International Conference on Materials Physics and Composites (ICMPC 2024) undoubtedly provides a valuable communication platform for experts, scholars, researchers and practitioners in the field of materials science around the world. The conference was successfully held in Chengdu, China from May 24th to 26th, 2024 via virtual form, establishing a forum to gather the world’s top wisdom and strength to discuss the latest research results, technological advances and future development trends in materials physics and composites. A number of well-known scholars and experts were invited to deliver keynote speeches, and oral presentations and poster sessions were set up to provide more opportunities for the participants to communicate and demonstrate. These activities not only promoted the collision and integration of academic ideas, but also deepened the friendship and cooperation among the participants. This Proceedings, as one of the important outcomes of ICMPC 2024, contains many excellent papers submitted during the conference. These papers cover a wide range of research directions in materials physics and composites, including but not limited to the Synthesis and Characterization of Novel Materials, Physical Properties and Structural Characterization of Materials, Preparation and Application of Composites, and Mechanical Properties of Materials, etc. Each paper is the result of the authors’ hard work and wisdom, and shows the latest progress and research results in the field of materials science. In the process of reviewing the papers, we strictly followed the academic standards and criteria, and invited well-known scholars and experts in related fields to be the reviewers. After several rounds of meticulous evaluation and screening, we have finally selected the papers with innovative, prospective and practical value for this Proceedings published in IOP Press-Journal of Physics: Conference Series. We believe that the publication of these papers will not only provide useful reference for researchers in the field of materials science, but also further promote the development and progress of materials science Looking ahead, materials science will continue to play an important role in scientific and technological progress and social development. We look forward to further strengthening the communication and cooperation in the field of materials science worldwide through international academic conferences such as ICMPC 2024, and jointly promoting the prosperity of materials science. Finally, we would like to express our heartfelt thanks to all the experts, scholars, researchers, committee members and staff who have participated in ICMPC 2024. It is thanks to your hard work and selfless dedication that this conference has been a great success. We look forward to continuing to work together with you in the future to create a better future for materials science. The Committee of ICMPC 2024 List of Committee Member is available in this pdf.

Enhancement of oral bioavailability of ibrutinib using a liposil nanohybrid delivery system.

Liposils, synthesized via the liposome templating method, offer a promising strategy for enhancing liposome stability by employing a silica coating. This study focuses on the development of nanocarriers utilizing silica-coated nanoliposomes for encapsulating the poorly water-soluble drug, ibrutinib. Ibrutinib-loaded nanoliposomes were meticulously formulated using the reverse-phase evaporation technique, serving as templates for silica coating, resulting in spherical liposils with an average size of approximately 240 nanometers. Comprehensive characterization of the liposil's physical and chemical properties was conducted using various analytical methods, including dynamic light scattering, transmission electron microscopy, Fourier-transform infrared spectroscopy, and X-ray diffraction analysis. Liposils demonstrated superior performance compared to ibrutinib-loaded nanoliposomes, showing sustained drug release profiles in simulated intestinal fluids and resistance to simulated gastric fluid, as confirmed by dissolution studies. Moreover, ibrutinib liposils exhibited a significant increase in half-life (4.08-fold) and notable improvement in bioavailability (3.12-fold) compared to ibrutinib suspensions, as determined by pharmacokinetic studies in rats. These findings underscore the potential of liposils as nanocarriers for orally delivering poorly water-soluble drugs, offering enhanced stability and controlled release profiles, thereby improving bioavailability prospects and therapeutic efficacy. This approach holds promise for addressing challenges associated with the oral administration of drugs with limited solubility, thereby advancing drug delivery technologies and clinical outcomes in pharmaceutical research and development.

Green Synthesis, Characterization and Study of Physical Properties of New Nanocomposite and Used as Adsorbent Surface and Photocatalyst for Waste Water Treatment

Green Synthesis, Characterization and Study of Physical Properties of New Nanocomposite and Used as Adsorbent Surface and Photocatalyst for Waste Water Treatment

Investigation and Characterization of Physical Properties and Phonon modes of ZnO/ PVA/PANI for Photonic Crystals application

Investigation and Characterization of Physical Properties and Phonon modes of ZnO/ PVA/PANI for Photonic Crystals application

Characterization of a decellularized pericardium extracellular matrix hydrogel for regenerative medicine: insights on animal-to-animal variability.

In the past years, the use of hydrogels derived from decellularized extracellular matrix (dECM) for regenerative medicine purposes has significantly increased. The intrinsic bioactive and immunomodulatory properties indicate these materials as promising candidates for therapeutical applications. However, to date, limitations such as animal-to-animal variability still hinder the clinical translation. Moreover, the choice of tissue source, decellularization and solubilization protocols leads to differences in dECM-derived hydrogels. In this context, detailed characterization of chemical, physical and biological properties of the hydrogels should be performed, with attention to how these properties can be affected by animal-to-animal variability. Herein, we report a detailed characterization of a hydrogel derived from the decellularized extracellular matrix of bovine pericardium (dBP). Protein content, rheological properties, injectability, surface microstructure, in vitro stability and cytocompatibility were evaluated, with particular attention to animal-to-animal variability. The gelation process showed to be thermoresponsive and the obtained dBP hydrogels are injectable, porous, stable up to 2weeks in aqueous media, rapidly degrading in enzymatic environment and cytocompatible, able to maintain cell viability in human mesenchymal stromal cells. Results from proteomic analysis proved that dBP hydrogels are highly rich in composition, preserving bioactive proteoglycans and glycoproteins in addition to structural proteins such as collagen. With respect to the chemical composition, animal-to-animal variability was shown, but the biological properties were not affected, which remained consistent in different batches. Taken together these results show that dBP hydrogels are excellent candidates for regenerative medicine applications.

Preparation and characterization of physical properties of molded pulp from empty fruit bunches of oil palm

This research aims to determine the impact of pretreatment on empty fruit bunches (EFB) of palm oil fibers before the pulping process on the quality of the molded pulp produced. The study includes EFB fiber pretreatment processes, pulp production, pulp molding, physical characteristic analysis, and molded pulp performance evaluation. The pulp production process involves acid-base hydrolysis reactions. The produced molded pulp is done manually. Characterization of the molded pulp includes measurements of paper grammage, thickness, density, and moisture content. The characteristics of pulp produced from pretreated EFB fibers are as follows: an average grammage value of 415.48 g/m², paper thickness of 1.53 mm, water absorption capacity of 13.33-33.33%, density of paper of 0,026 x 106 - 0,027 x 106 g/m3, and a smooth surface morphology. Meanwhile, the characteristics of pulp produced from without pretreatment EFB fibers include an average grammage value of 372.18 g/m², paper thickness of 0.77 mm, water absorption capacity of 20.34-43.21%, density of paper of 0,004 x 106 - 0,008 x 106 g/m3, and a rough surface morphology due to pores on the fiber surface.

Active interlocking metasurfaces enabled by shape memory alloys

Interlocking metasurfaces (ILMs) are a newly developed joining technology that relies on arrays of interlocking features that transmit force and constrain motion between adjoining bodies in one or more directions. This study explores harnessing the shape memory effect (SME) in Nickel-Titanium shape memory alloys (NiTi SMAs) in structures fabricated using additive manufacturing (AM) to advance the development of active ILMs by creating unit cells that open or close at specific temperatures. The study encompasses designing and fabricating two distinct interlocking array configurations using near-equiatomic NiTi powder and the laser powder bed fusion (L-PBF) AM technique, following a previously developed AM process optimization framework to manufacture defect-free parts. To guide the design process, finite element analysis (FEA) was employed to predict strain values during engage-disengage cycles. The martensitic transformation characteristics of the ILMs were characterized. Thermomechanical testing revealed that the ILMs demonstrate high locking force once engaged, coupled with complete shape recovery and good cyclic stability. Digital image correlation (DIC) was also employed to validate the FEA predictions during the engage-disengage cycles. The results indicate that NiTi SMA-based ILMs can be designed and fabricated into complex shapes using L-PBF. By leveraging the SME, the functionality of an ILM can be improved upon. The combination of computational modeling, additive manufacturing, and thermomechanical and physical property characterization provides a framework for designing future ILMs out of active materials.

Study on structural and optical properties of Tb3+ co-doped Au glasses for green optical application

This report investigates the structure and optical properties of Tb3+ co-doped Au glasses, with a focus on their applicability in green luminescent optical behavior. The study of Tb3+ co-doping in the presence of Au nanoparticles (AuNPs) within glass matrices. The starting materials include SiO2, Al2O3, B2O3, CaO, Sb2O3, Na2O, K2O, SnO2, SeO2, Tb2O3, and AuNPs. Glass fabrication employs the conventional melt quenching technique, followed by comprehensive characterization of physical, optical, luminescence, and structural properties. The density values reported for the glass, ranged from 2.8269 to 2.8359 g/cm3, molar volume was 26.3382 to 26.2591 cm3/mol, and refractive index was 1.5438–1.5526. The absorption spectra consist of three absorption bands that are located at 524, 1894, and 2178 nm and are assigned to 7F6 → 5D4, 7F6 → 7F0,1,2, and 7F6 → 7F3, respectively. Photoluminescence (PL) and radioluminescence (RL) show similar trend and the optical properties are scrutinized using a spectrofluorometer. Size of the nanoparticle was evaluated and show around 8–16 nm and interplanar distance showing 2.1 Å. This study underscores the potential of Tb3+ and Au co-doped materials as promising for green optical applications.

Designing biodegradable aqueous biphasic systems for the selective separation of enzymes

In this work, the salting-out strength of reline eutectic mixture in aqueous solution of the non-ionic surfactant Triton X-102 has been demonstrated at temperatures between 298.15 and 323.15 K as a preliminary step to be employed in downstream operations of a biotechnological process. The phase diagrams data of reline-based Aqueous Two Phase Systems (ATPS) have been correlated using empirical models based on exponential and polynomial equations. The tie-lines have been empirically ascertained through physical properties characterization and Othmer-Tobias equation was proposed to correlate those data. After having studied the effect of the proposed reline eutectic mixture on two model enzymes (protease and lipase), the performance of this ATPS for selectively separating them was evaluated for three different feed compositions on the same tie-line, demonstrating their pertinence to segregate the lipase to one of the phases (yield about 95 %) and the protease to the other phase (yield about 98 %). These promising results are interesting for application in biotechnological reactions where proteases have been proved to be deleterious for lipases activity, as the biocompatibility of the proposed platform does not involve drastic negative effects on any of the enzymes.

A comparative study between aqueous and methanol solutions of barium hydroxide: implications for applying barium protectants in gypsification calcareous relics

Gypsification is a common problem in weathered calcareous relics. In previous studies, the solutions of barium hydroxide in water and methanol were used as protectants for gypsification calcareous relics and showed significant differences in permeability. In this study, the underlying reasons for permeability differences between these two solutions were investigated using optical microscopy, ultraviolet–visible spectrophotometry, X-ray diffractometry, Fourier transform infrared spectroscopy, the phenolphthalein test and physical property characterizations. The results indicated that the permeability differences were primarily caused by the solutions’ reactivity. Specifically, owing to the high reactivity of barium hydroxide in water, it reacted rapidly with atmospheric CO2 and gypsum (the weathering product) to generate barium carbonate, barium sulfate and calcium hydroxide precipitates. These precipitates hindered the penetration of solution into weathered relics. In contrast, barium hydroxide in methanol did not react with atmospheric CO2 or weathered relics, which also kept the solution in a liquid state during the infiltration process. Therefore, the solution of barium hydroxide in methanol exhibited high permeability. Based on the above findings, this study is meaningful for applying barium protectants in the conservation of gypsification calcareous relics.

3D-Printed Biomimetic Hydroxyapatite Composite Scaffold Loaded with Curculigoside for Rat Cranial Defect Repair.

The treatment of various large bone defects has remained a challenge for orthopedic surgeons for a long time. Recent research indicates that curculigoside (CUR) extracted from the curculigo plant exerts a positive influence on bone formation, contributing to fracture healing. In this study, we employed emulsification/solvent evaporation techniques to successfully fabricate poly(ε-caprolactone) nanoparticles loaded with curculigoside (CUR@PM). Subsequently, using three-dimensional (3D) printing technology, we successfully developed a bioinspired composite scaffold named HA/GEL/SA/CUR@PM (HGSC), chemically cross-linked with calcium chloride, to ensure scaffold stability. Further characterization of the scaffold's physical and chemical properties revealed uniform pore size, good hydrophilicity, and appropriate mechanical properties while achieving sustained drug release for up to 12 days. In vitro experiments demonstrated the nontoxicity, good biocompatibility, and cell proliferative properties of HGSC. Through alkaline phosphatase (ALP) staining, Alizarin Red S (ARS) staining, cell migration assays, tube formation assays, and detection of angiogenic and osteogenic gene proteins, we confirmed the HGSC composite scaffold's significant angiogenic and osteoinductive capabilities. Eight weeks postimplantation in rat cranial defects, Micro-computed tomography (CT) and histological observations revealed pronounced angiogenesis and new bone growth in areas treated with the HGSC composite scaffold. These findings underscore the scaffold's exceptional angiogenic and osteogenic properties, providing a solid theoretical basis for clinical bone repair and demonstrating its potential in promoting vascularization and bone regeneration.

Characterization of physical and chemical properties of dietary fiber from grain bran and its regulation of gut microbiota and metabolite to prevent colitis

Grain bran dietary fiber (DF) has the effect of promoting intestinal health and is worth being studied. In the present study, the physicochemical properties and prevention effect of DF on ulcerative colitis (UC) were investigated. The results showed that the optimal extraction conditions were determined as α-amylase (350 U/g, 70 °C, pH 7.0, 2.5 h) and papain (100 U/g, 60 °C, pH 7.0, 1.5 h), resulting in a yield of 83.81% for DF. Moreover, DF exhibited unique physicochemical properties contributing to its preventive effects, as evidenced by its ability to mitigate symptoms such as hematochezia, immune inflammation, and impaired intestinal barrier in UC mice. The underlying mechanism can be attributed to the regulation of phenylalanine, tyrosine and tryptophan biosynthesis pathway and maintenance of intestinal microbial homeostasis. Therefore, our study suggests that grain bran DF holds potential for the prevention of UC, providing a basis for the development and utilization of grain bran.

A Novel MXene@MOF@Pt NPs-Based Enzyme-Free Electrochemical Sensor for Highly Sensitive Detection of Hydrogen Peroxide Released from Living Cells

Rapid and accurate detection of hydrogen peroxide (H2O2), an important reactive oxygen species (ROS) released from living cells, is of great significance for early diagnosis of tumors. Here, a high sensitive enzyme-free electrochemical sensor for the detection of H2O2 released from living cells was constructed based on MXene@ZIF-8@Pt NPs nanocomposites. Through the characterization of physical and chemical properties, it was observed that Pt NPs with excellent catalytic activity were uniformly supported on MXene@ZIF-8, which exhibited excellent conductivity and large specific surface area. Thanks to the significantly enhanced catalytic activity derived from the successful integration of MXene, ZIF-8 and Pt NPs, under the optimal conditions, the sensing platform based on MXene@ZIF-8@Pt NPs exhibited a wide linear range from 355.4 nM to 21.75 mM, with a limit of detection as low as 120.9 nM, while showing satisfactory reproducibility and selectivity. Furthermore, the developed electrochemical sensor enables real-time monitoring of H2O2 released from living Hela cells under N-formylmethionyl-leucyl-phenylalanine stimulation. Overall, the MXene@ZIF-8@Pt NPs developed in this article will become a promising candidate in monitoring physiological processes.