Decline In Physical Fitness Research Articles

Joint exploration of network pharmacology and metabolomics on the effects of traditional Chinese medicine compounds in weaned yaks

IntroductionChinese herbal medicines are relatively inexpensive and have fewer side effects, making them an effective option for improving health and treating diseases. As a result, they have gained more attention in recent years. The weaning period is a critical stage in the life of yaks, often inducing stress in calves. Weaning stress, along with dietary changes, can lead to a decline in physical fitness and immune function, making yaks more susceptible to diarrhea and resulting in high mortality rates during this period. Therefore, our study aimed to address this issue by incorporating traditional Chinese medicine (TCM) formulas into the diet of yaks during the weaning period.MethodsFollowing a dialectical analysis, three TCM formulas, mainly composed of Paeonia lactiflora, Coptis chinensis, and Dandelion, were identified for their anti-inflammatory, antioxidant, and immune enhancing potentials. We explored the possible molecular mechanisms of these TCM formulas using network pharmacology analysis and investigated their effects on the physiology of yaks through metabolomics.ResultsNetwork pharmacology analysis revealed several key target proteins in the protein–protein interaction (PPI) network between three formulas and immune-related genes, including PIK3R1, PIK3CA, JAK2, PTK2, and PYPN11. The key target proteins in the PPI network associated with metabolism-related genes included ENPP1, CYP1A1, PTGS1, members of the CYP1 family, and EPHX2. GO analysis of co-targets revealed highly enriched pathways such as protein phosphorylation, plasma membrane, and one-carbon metabolic processes. Metabolomics revealed significant changes in the abundance of metabolites including dimethyl sulfoxide, tyrphostin A25, and thromboxane A2 in the intestines of weaned yaks supplemented with these Chinese herbal compounds. Significant changes were also observed in pathways such as vitamin A metabolism, chloroalkane, and chloroalkene degradation.DiscussionBased on these findings, it can be inferred that TCM formulas improve the physical fitness of weaned yaks by enhancing antioxidant capacity, boosting immunity, and reducing intestinal inflammation. This study preliminarily elucidates the pharmacological mechanisms by which TCM formulas prevent diarrhea and improve physical fitness in weaned yaks through metabolomics and network pharmacology, paving the way for further evaluation of the effectiveness of these three formulas.

Association of Preoperative Physical Fitness With Post-Esophagectomy Pneumonia in Older With Locally Advanced Esophageal Cancer: An Exploratory Prospective Study.

Currently, there is a lack of evidence of prehabilitation during neoadjuvant chemotherapy (NAC) to prevent pneumonia of older patients. This study aimed to investigate the association of preoperative physical fitness after NAC with post-esophagectomy pneumonia in older patients with locally advanced esophageal cancer (LAEC). This single-center exploratory prospective cohort study included 80 patients aged ≥ 65 years with LAEC scheduled for curative esophagectomy after NAC between 2021 and 2023. The post-NAC short incremental shuttle walk test (ISWT) by sex was established using the Youden index. The association of the post-NAC short ISWT with postoperative pneumonia was investigated via Firth's penalized logistic regression model with statistical significance set as two-tailed p < 0.05. A total of 69 patients were analyzed. The mean post-NAC ISWT values were 353.5 m. Short ISWT distance was defined as ≤ 395 and ≤ 195 m for men and women, respectively. Postoperative pneumonia developed in 17 (25%) patients. Short post-NAC ISWT distance was significantly associated with postoperative pneumonia (adjusted odds ratio: 1.840, 95%CI: 1.760-28.440, p = 0.004). Decline in physical fitness was associated with post-esophagectomy pneumonia, which may be a key targeted factor of prehabilitation during NAC for older patients with LAEC.

A longitudinal study to COVID-19 infection among university students: Physical fitness changes and psychological responses

BackgroundThe impact of COVID-19 infection on physical and mental health of young adults remains unclear. This study aimed to investigate the changes in the physical fitness three months after recovering from acute COVID-19 infection, and examine if the infection could also influence the mental health of university students. MethodsA total of 460 university students (mean age 18.9 ± 1.3 years, with 30 males and 27 females uninfected with COVID-19) volunteered for the study. Participants underwent a fitness test initially, followed by another physical fitness test and a mental health assessment three months after the infection of COVID-19. Physical fitness tests included body composition, flexibility, cardiorespiratory fitness, muscle strength, and muscular endurance. Mental health was assessed using the Depression-Anxiety-Stress Self-Assessment Scale (DASS-21), the Pittsburgh Sleep Quality Inventory (PSQI), and the Post-Traumatic Stress Disorder Self-Assessment Scale (PTSD). ResultsThree months after acute COVID-19 infection, the physical performance of university students had decreased compared to pre-infection levels by approximate 3–15 % (p < 0.05). Regarding mental health, a notable difference was observed in sleep quality, with the positive group scoring 19 % higher than the negative group (p < .05, d = .44). Sex (β = .164, p < .05), previous infection (β = .277, p = .019) and anxiety (β = .373, p = .002) were predictive of PSQI scores, accounting for 37.5 % of the variance. ConclusionsAll participants experienced a decline in physical fitness compared to their pre-infection levels, regardless of infection status. Those who had been infected exhibited poorer sleep quality compared to their non-infected peers. Prior COVID-19 infection and higher anxiety levels may contribute to poorer sleep quality.

Abstract A015: Aging limits stemness and tumor development in the lung by reprogramming iron homeostasis

Abstract Aging is the most important and well-recognized risk factor for cancer. Aging leads to systemic decline of physical fitness, significantly changing the macroenvironment from the early tumor initiation to the terminal stage of metastasis. However, the underlying mechanisms only start to emerge. Here, using physiologically aged autochthonous genetically engineered mouse models (GEMMs) and primary cells, we demonstrate that aging suppresses lung cancer initiation and progression by degrading stemness of the alveolar cell of origin. Using single-cell transcriptomics, we uncover a distinct compositional landscape of cancer cell subsets in aged lung tumors, revealing a delay in the molecular progression of the lung lesions and an age-specific gene expression signature. Interestingly, key components of this gene signature were traced back to the aged cell of origin. Furthermore, the age-specific signature derived from GEMMs was predictive of patient age in human lung cancer, indicating conservation of the age-associated changes across species. Interestingly, our preliminary data suggested that tumor cells derived from aged tumor-bearing mice displayed higher metastatic potential, indicating that different mechanisms may govern tumor initiation and metastasis. Functional interrogation of the age-specific gene signature revealed that the loss of stemness and tumorigenic capacity is underpinned by aging-associated induction of the transcription factor NUPR1. We find that NUPR1 is induced in the cell of origin in aged mice and humans, which leads to a functional iron insufficiency in the aged cells. Genetic inactivation of the NUPR1 or iron supplementation restores stemness and promotes tumorigenic potential of aged alveolar cells. Conversely, targeting NUPR1 is detrimental to young alveolar cells by promoting ferroptosis. We find that aging-associated DNA hypomethylation at specific enhancer sites results in elevated NUPR1 expression, which is recapitulated in young cells by inhibition of DNA methylation. We uncover that, unlike the young, aged alveolar cells are functionally iron insufficient, which leads to loss of stemness and resistance to ferroptosis. Our results indicate that aging-associated reprogramming of the cell of origin determines tumor initiation potential, alters trajectory of tumor evolution and produces age-dependent vulnerabilities. These findings demonstrate that aging fundamentally changes the biology of lung cancer, shedding light on novel therapeutic modulation of cellular iron homeostasis or ferroptosis in regenerative medicine and in cancer prevention for the elderly population. Citation Format: Xueqian Zhuang, Qing Wang, Simon Joost, Alexander Ferrena, Melissa Blum, Klavdija Krause, Zhuxuan Li, Deyou Zheng, Emily S Wong, Tuomas Tammela. Aging limits stemness and tumor development in the lung by reprogramming iron homeostasis [abstract]. In: Proceedings of the AACR Special Conference in Cancer Research: Tumor-body Interactions: The Roles of Micro- and Macroenvironment in Cancer; 2024 Nov 17-20; Boston, MA. Philadelphia (PA): AACR; Cancer Res 2024;84(22_Suppl):Abstract nr A015.

Whole-body-electro-myostimulation for the care of inclusion body myositis-A case report.

External muscle stimulation, possibly combined with active muscle contraction, could improve physical functioning and performance in inclusion body myositis. Inclusion body myositis (IBM) is a chronic, progressive inflammatory muscle disease with largely unknown causes. It typically affects men more than women, usually beginning in the latter half of life. IBM leads to muscle weakness and wasting, especially in the arms and legs, which significantly impairs daily functioning and complicates participation in exercise training. Few studies have examined the impact of physical training on fitness, inflammation markers, and quality of life in IBM patients. The patient, a Caucasian male (78.3 kg, 174.0 cm, born October 1948), was diagnosed with IBM in October 2011. From October 2017 to September 2019, he underwent exercise training focused on external muscle stimulation combined with active muscle contractions. Regular assessments included cardiopulmonary exercise testing, functional tests (6-min walking test, modified timed up and go test, modified chair rise test), lung function exams, blood parameters, body composition, and quality of life questionnaires. The decline in physical fitness may have been slowed during the intervention period, as indicated by some improvements like peak oxygen uptake and the functional test results while other parameters remained unchanged or declined like peak power output, fat-free mass or lung functioning. However, a recurrence of his prostate cancer after treatment with androgen deprivation therapy may have led to further declines and thus increased muscle wasting. The data may suggest that supportive exercise programs focusing on external muscle stimulation, possibly combined with active muscle contraction, might improve physical functioning, exercise performance, and quality of life in IBM management.

Effects of a 4-Week Detraining Period After 12 Weeks of Combined Training Using Different Weekly Frequencies on Health-Related Physical Fitness in Older Adults.

Detraining refers to the decline in physical fitness that occurs after the cessation of exercise, compromising the adaptations resulting from regular exercise training. To understand how long the benefits acquired from an exercise program can be maintained, the present study evaluated the detraining effects of a 4-week exercise cessation period in older adults who performed combined training at various weekly frequencies for 12 weeks. This randomized controlled trial assigned participants to one of two training programs: a combined training program twice a week (CT2) or four times a week (CT4) over a period of 12 weeks, followed by a four-week detraining period. The resistance training consisted of six bodyweight exercises, while the aerobic training involved either walking or running. Both the CT2 and CT4 groups completed the same total training volume and overload each week; the only difference was the number of training sessions per week. Assessments were conducted at baseline, after the training period, and after the detraining period, and included the 30-s and five-repetition chair-stand tests, isometric handgrip strength, body mass index (BMI), waist circumference, and waist-to-height ratio. Thirty-one participants completed the study (CT2: 17 and CT4: 14). The groups presented similar attendance records during the training period (CT2: 96 ± 18% versus CT4: 94 ± 19%). After the 12-week training period, CT2 and CT4 improved lower limb strength, CT2 improved upper limb strength, and CT4 reduced waist circumference and waist-to-height ratio compared to baseline. After the 4-week detraining period, the lower limb strength remained improved in both groups (CT2: 4 ± 1 repetition; p < 0.001 and CT4: 4 ± 1 repetition; p < 0.001) when compared to the corresponding baseline values. The handgrip strength decreased in CT2 compared to post-training values. And the body composition benefit in CT4 was not sustained after detraining. The effects of 4 weeks of detraining after 12 weeks of training performed two or four times per week are similar on some but not all health-related physical fitness parameters.

The effect of age on musculoskeletal injury compensation costs in South Australian professional urban firefighters: A cohort study.

Firefighting is recognised as a physically demanding occupation involving exposure to hazardous environments and activities. An aging workforce combined with the age-related decline in physical fitness may result in increased future workers' compensation expenditure for fire service organisations. The objective of this research was to investigate the costs associated with musculoskeletal sprain and strain injury and the impacts of age and injury location on Workers' Compensation claims submitted by professional urban firefighters. Claim rates, direct costs, and days lost were extracted from a professional Fire Service organisation's workers' compensation claim database for financial years between 2011 to 2018. The mean cost per claim increased with age, with a mean claim cost of the 60-70-year-old group over 10 times more than the 20-29-year-old group. The mean days lost per claim were also higher for claims submitted by firefighters aged over 50. Older firefighters miss more workdays when injured and are associated with increased claims costs, particularly those in the 60-70-year group. With an aging workforce, Fire Service organisations must implement appropriate management and prevention strategies to reduce the potential risks associated with an aging workforce.

Secular trends in underweight, overweight, and physical fitness of girls and boys aged 16–18 in eastern Poland from 2006 to 2016–2021

Introduction: Significant changes in the nutrition and physical fitness of children and adolescents have been observed in many countries around the world. The purpose of this study is to determine the changes in the prevalence of underweight, normal BMI, and overweight, as well as in the physical fitness of girls and boys from eastern Poland. Materials and methods: The study was conducted over the years 2006–2021. BMI was calculated, and physical fitness was assessed using the EUROFIT test. The results were statistically analyzed. Results: Minor changes in underweight were observed, and even a re-duction in its prevalence among girls was noted. However, a significant increase in the frequency of overweight was identified. Meanwhile, a decrease in the level of physical fitness in both girls and boys was recorded. These changes, however, were not uniform across all fitness abilities. Conclusions: The systematic decline in physical fitness among the examined girls and boys, particularly in cardiovascular-respiratory endurance, underscores the necessity for continued regular monitoring of the health of children and adolescents.

Changes in Catalan Adolescents’ Agility over Two Decades: A Temporal Trend Study

Physical fitness is considered an important indicator of health in adolescents. Despite the recognized benefits of regular physical activity, recent studies indicate a decline in physical fitness among adolescents, including agility, a key component of fitness often overlooked in research. This study aimed to investigate trends in agility among urban Catalan adolescents over two decades. A total of 1439 students, aged 13–15 years, participated in the 8 × 10 m shuttle run test between 2002 and 2022. The results revealed a significant decline in agility performance across both boys (F(3,839) = 392, p &lt; 0.001, ηp2 = 0.584) and girls (F(3,593) = 414, p &lt; 0.001, ηp2 = 0.677) over time, with notable differences observed between consecutive five-year periods. The findings underscore the urgency of addressing declining physical fitness among adolescents and advocate for enhanced physical education programs and community-based interventions to promote regular physical activity. Recognizing the importance of agility and other aspects of physical fitness in adolescent health, policymakers, educators, and healthcare professionals are urged to collaborate on initiatives to mitigate the risk of future health issues. Further research is recommended to explore the multifaceted influences on adolescent physical fitness and develop targeted interventions to improve overall health outcomes in this population.

Effects of physical inactivity behavior during COVID-19 pandemic on physical fitness, body composition, inflammatory cytokine, and immunocytes in older adults: A retrospective and prospective study

The prolonged period of COVID-19 has ingrained physical inactivity as a habit, leading to a reluctance to move. This has resulted in a decline in physical fitness and the loss of a healthy body composition. While this trend is particularly noticeable among the older adults, its impact on the immune cell defense system, which is crucial for minimizing viral infections, remains unclear. This study aimed to investigate the physical fitness, body composition, cytokines and immunocytes of older adults who engaged in physical activity (PA) before the COVID-19 pandemic but had to stop it due to the lockdown. A total of 172 older adults aged 61 to 85 years participated in this study: 90 in non-PA group (NPAG, 34 men and 56 women), and 82 in PA group (PAG, 29 men and 53 women). Physical inactivity was 45.13 ± 5.67 weeks in the NPAG and 1.70 ± 0.43 weeks in the PAG. Although there was no significant difference in calorie intake, PA volume showed a significant decrease in NPGA (P < 0.001). VO₂max, strength, and sit-ups decreased in NPAG, whereas they maintained or increased in PAG (Ps < 0.001). NPAG experienced an increase in fat mass (∼33.0 %), along with a decrease in muscle mass (∼10.4 %), but PAG showed slight increases (∼1.1 % vs. ∼1.5 %, Ps < 0.001). Interleukin-6 (∼38.9 %), tumor necrosis factor-α (∼38.3 %), and C-reactive protein (∼33.6 %) increased, whereas immunocytes decreased in NPAG (Ps < 0.001). In contrast, those in PAG showed the opposite phenomenon. This study indicates that even during the COVID-19 situation, maintaining active PA in the older adults helps retain beneficial physical fitness and body composition, reduces inflammatory factors, and contributes to preserving or enhancing the function of immunocytes.

Current Status and Optimization Strategies of Physical Fitness Training for the Elderly in the Digital Age

With the advent of digital technology and the improvement of people's living standards, the decline of physical fitness among the elderly has become an urgent problem to be addressed. Physical fitness typically includes abilities such as strength, flexibility, agility, speed, coordination, and other capacities, which not only play an important role in athletic performance but are also crucial for the daily lives of the elderly. This study investigates the current state of physical fitness training for the elderly in the digital age and aims to explore the optimization of scientific approaches and the role of digital products in improving training strategies. Through literature research and logical analysis, this paper collects and analyzes related data to further explore the status of the elderly's physical fitness training and their training strategies under the empowerment of science and technology. The investigation of related materials reveals that currently, the elderly have a low awareness of scientific training, especially regarding the concept of scientific training. Moreover, the main activities engaged in by the elderly for physical fitness training are fitness Qigong, square dancing, and other similar projects, which indicates that the elderly tend to engage in aerobic exercises and meet their psychological needs through group activities. By integrating current large-scale digital technologies and scientific products, the paper proposes optimization strategies for the elderly's training. These include utilizing robot learning and smart devices to collect information through smart devices, analyzing the collected data using large models to develop individualized training programs to improve efficiency. Additionally, wearable devices like smart bracelets, Firstbeat heart rate monitoring systems, and Gymaware monitoring systems can collect data on the body, reflecting physical conditions and further reducing the risk of injury. VR virtual interactive technology can be used to train cognitive responses, and VBT technology can make exercises more efficient, reducing the risk of injury. As technology continues to advance and awareness increases, achieving a healthy China is within reach.

Effects of fermented milk intake and physical activity on the suppression of age-related decline in physical fitness among the elderly.

Physical deterioration in the elderly can lead to disability and mortality. Although the intake of fermented milk has been recently attracting attention as a proposed measure to prevent physical weakness, studies and findings are limited. Here, we investigated the effect of intake of fermented milk products on suppression of age-related decline in physical fitness through a long-term epidemiological study of community-dwelling elderly people who are capable of independent living. A retrospective analysis was conducted on 581 elderly people aged 65-92 years from the Nakanojo Study, with the addition of a 5-year prospective analysis on 240 elderlies. Subjects were arbitrarily grouped on the basis of questionnaire estimates of fermented milk products intake (<3 or ≥3 days/week) and pedometer/accelerometer-determined patterns of physical activity (<7,000 or ≥7,000 steps/day). After adjustment for potential confounders, the retrospective study showed that the group consuming fermented milk products ≥3 days/week showed significantly faster walking speeds than the <3 days/week group. The group taking ≥7,000 steps/day had a significantly faster walking speed than the group taking <7,000 steps/day. Those who did both walked the fastest, indicating an additive effect. Adding protein or energy intake as a covariate to the potential confounders found a correlation between the intake of fermented milk products and walking speed, suggesting that the effect of fermented milk products consumption is independent of nutritional intake status, due to the beneficial properties of bacteria included in fermented milk. The 5-year prospective study confirmed a clear relationship between the frequency of consumption of fermented milk products and the suppression of preferred walking speed decline. Our findings suggest that habitual intake of fermented milk contributes to the suppression of walking speed decline in elderly people.

Physical fitness decline and career paths: a longitudinal study of medical undergraduates

IntroductionExercise enhances one's health and competitiveness. A strong physical fitness status can pave the way for a promising future. This study presents the time-based trends in physical fitness indicators—including height, weight, BMI, lung capacity, dash, long-distance running, and standing long jump—among medical undergraduates during their university years. Additionally, we analyzed the impact of students' physical fitness on their career paths.MethodWe conducted a retrospective database study by collecting physical fitness test data and career paths information for 634 medical students from a university in southwestern China. These students graduated in 2022. The career paths included pursuits in further studies, employment, and unemployment. To detect differences in these aspects, we used the t-test and Chi-square test.ResultsOur study indicates a significant declining trend in the physical fitness of medical students during their university years. The changes observed between the first and fourth tests are as follows:Weight (kg): 58.52 ± 10.48 to 60.73 ± 12.07, P < 0.00BMI (kg/m^2): 20.79 ± 2.74 to 21.24 ± 3.06, P < 0.0050-m dash (s): 8.91 ± 0.99 to 9.25 ± 1.11, P < 0.00Standing long jump (cm): 187.74 ± 30.98 to 182.59 ± 32.25, P < 0.00800-m run for females (min): 3.84 ± 0.47 to 4.48 ± 0.85, P < 0.001000-m run for males (min): 3.98 ± 0.63 to 4.62 ± 0.87, P < 0.00Sit-ups for females (count): 30.39 ± 7.5 to 29.03 ± 8.82, P < 0.00Upon analyzing the correlation between changes in physical fitness and career paths, students with stable or decreased BMI had better post-graduation outcomes compared to students with increased BMI.ConclusionsMedical students show a declining trend in physical fitness during their undergraduate years. A good physical health status is beneficial for achieving better career paths. Medical students should place greater emphasis on physical exercise during their time in school.

1930년대 말 국민체력저하 문제의 대두와 사회적 대응

In 1936, General Teraiichi Derauchi raised concerns about the declining national physical fitness during a regular assembly. This statement paved the way for the establishment of the Welfare Department in 1938. The recognition of the national physical fitness decline as an urgent issue by the army emerged around the mid-1930s. The army had been continuously analyzing the results of conscription examinations. Experiences utilizing the results of conscription examinations in the “Excellent Excellent young man Village Award(優良壯丁市町村表彰)” project conducted by the Asahi Shimbun in 1934, along with the appointment of Chikahiko Koizumi(小泉親彦) as the Director of the Medical Officer, prompted a re-evaluation of the physical fitness issue among servicemen. Subsequently, Koizumi's analysis of the national physical fitness issue led to General Koizumi's remarks. Subsequently, through academic research and mass media, the issue spread socially. Initially, the “Japan Society for the Promotion of Science(日本學術振興會)” established a related committee to initiate scientific examination. The research findings highlighted the necessity for accurate data to assess the nation's physical fitness. These academic research results provided a policy definition for 'physical fitness' and laid the groundwork for the National Physical Fitness Law(國民體力法) enacted in 1940. Asahi Newspaper(朝日新聞社), a prominent mass media outlet, provided a platform for the formation of societal consensus on the issue of national physical fitness. Particularly noteworthy is the 'National Physical Fitness Improvement Symposium(國民體力向上座談會)' held in June 1937. Government officials, along with experts from various fields including academia, labor, and sports, attended this symposium to discuss the causes of the decline in national physical fitness and potential improvement measures. Not only were policy perspectives discussed, but also vividly conveyed were the issues faced in practical settings. As a result of these processes, societal awareness of the issue of national physical fitness spread, and there was a growing chorus calling for alternative solutions to address it. The discussions and awareness spread at the societal level would go on to have a significant impact on the subsequent policy-making process. In other words, the national importance of the issue of national physical fitness, symbolized by the establishment of the Welfare Department during the wartime period, was shaped not only by political responses but also by the convergence of societal interest and awareness.

Personalized pulmonary rehabilitation program for patients with post-acute sequelae of COVID-19: A proof-of-concept retrospective study.

Long-COVID patients present with a decline in physical fitness. The aim of this study is to reveal the impact of pulmonary rehabilitation (PR) on physical fitness, quality of life (QoL), and parameters of quantified thorax CT. Long-COVID patients enrolled in a 3-month PR program were retrospectively studied. PR included endurance and resistance training three times a week. Assessments pre- and post-rehabilitation included quantified chest CT, pulmonary function tests (PFT), six-minute walk test (6MWT), cardiopulmonary exercise test, and questionnaires: Hospital Anxiety and Depression Scale, post-COVID-19 Functional Status scale, Borg score, and EuroQol. Seventeen subjects (5M/12F), mean age 42 ± 13 years, were included. PR improved all questionnaires' results significantly. Only significant difference in PFT parameters was correlation between baseline total lung capacity (TLC) and difference in TLC pre- and post-rehabilitation (p = 0.002). 6MWT increased from 329 to 365 m (p < 0.001), VO2max changed from 21 to 24 mL/kg/min (p = 0.007), peak load increased from 116 to 141 Watt (p < 0.001). Blood volume in small pulmonary vessels of 1.25 to 5 mm2 in cross-sectional area (BV5%) was higher than observed in patients with acute COVID-19 infection. After rehabilitation, BV5% decreased from 65% to 62% (p = 0.020). These changes correlated directly with changes in TLC (p = 0.039). Quantified CT airway volume increased after rehabilitation (p = 0.013). After rehabilitation, TLC tended to normalize due to (re)opening of small airways, with decline in air trapping and recruitment of alveoli. Furthermore, this study revealed that pulmonary rehabilitation can improve QoL and physical fitness in long-COVID patients.

Associations between physical fitness, body composition, and heart rate variability during exercise in older people: exploring mediating factors.

Age-related changes in body composition affect physical fitness in older adults. However, whether the autonomic response is associated with body fat percentage and its implication for physical fitness is not fully understood. To understand the association between physical fitness, body composition, and heart rate variability in older people and its mediating factors. A cross-sectional study with 81 older adults was conducted, assessing Short Physical Performance Battery (SPPB), Two-minute Step Test (TMST), body composition, and cardiac autonomic response. Correlation and mediation analyses were performed. Body fat percentage negatively correlated with physical fitness (SPPB: r=-0.273, p=0.015; TMST: r=-0.279, p=0.013) and sympathetic activity (sympathetic nervous system (SNS) index: r=-0.252, p=0.030), yet positively correlated with parasympathetic tone (root mean square of successive differences (RMSSD): r=0.253, p=0.029; standard deviation of NN intervals (SDNN): r=0.269, p=0.020). Physical fitness associated with sympathetic nervous system index (SPPB: r=0.313, p=0.006; TMST: r=0.265, p=0.022) and parasympathetic nervous system index (TMST: r=-0.344, p=0.003). Muscle mass mediated body fat's impact on physical fitness, while physical fitness mediated body fat's impact on autonomic response. Body composition and cardiac autonomic response to exercise are associated with physical fitness in older people, highlighting a possible protective effect of muscle mass against the decline in physical fitness associated with increased body fat.

Secular trends in motor abilities of Xinjiang children and adolescents aged 7-18 years from 1985 to 2019.

To assessment the secular trend in physical fitness of children and adolescents aged 7-18 years in Xinjiang from 1985 to 2019. The data are derived from test scores of Xinjiang Chinese children and adolescents aged 7-18 years by the China National Student Health Monitoring Centre National Student Physical Fitness Monitoring in 1985, 1991, 1995, 2000, 2005, 2010, 2014, and 2019. The physical fitness indicators included speed, cardiorespiratory fitness, muscular strength, power, and flexibility. The overall physical fitness of Xinjiang children and adolescents aged 7-18 in Xinjiang demonstrated downward trend from 1985 to 2019. During the period from 1985 to 1995, the speed, power, and cardiorespiratory fitness improved significantly but worsened from 1995 to 2005. The pace of decline in physical fitness slowed down from 2005 to 2014. Some components of physical fitness improved, but most components of physical fitness continued to worsen from 2014 to 2019. In conclusion, the overall physical fitness of Xinjiang children and adolescents aged 7-18 years worsened from 1985 to 2019, and some relatively positive trends have been found in recent years. Trends in physical fitness vary among children and adolescents by gender and age, and these differences should be emphasized in the development of relevant physical fitness policies as well as interventions.

Effectiveness of an Educational Intervention on Prevention of health problems due to Internet addiction among students of selected college of New Delhi

Internet Addiction (IA) has been recognized as a global concern that can lead to sedentary lifestyles and a decline in physical fitness. Digital eye strain, pain in the upper body parts, obesity, insomnia, anxiety, and depression are health problems commonly reported among internet users. There is more requirement for internet use among students owing to their educational or research needs. There is an urgent need to sensitize students about the health hazards due to IA and ways to prevent them. Thecurrent studyevaluates the effectiveness of educational intervention on the prevention of health problems due to internet addiction and to find out the association of post-test knowledge and practice score with selected demographic variables Quantitative Experimental research with one group Pre-test, and Post-test design was conducted at PGDAV College, New Delhi among 54 college students using total enumeration sampling. The t-value (18.39) and (14.76) between pre-test and post-test knowledge and practice scores were statistically significant at 0.05 level of significance. In the current study, the educational intervention was effective in enhancing the knowledge and practice expressed on the prevention of health problems due to internet addiction. A significant association was found between post-test knowledge scores and the academic year. However, no significant association was found between post-test practice scores and selected variables.

Role of Sports Based on Big Data Analysis in Promoting the Physique and Health of Children and Adolescents

ABSTRACT Healthy body is the foundation of young people's growth. With the popularization and globalization of the Internet, multimedia technology is rapidly changing the impact of traditional media on the growth of young people. The current health situation of young people is not optimistic. The decline in physical fitness, obesity and psychological dysplasia of adolescents have aroused the concern of all sectors of society. In recent years, the emergence and dissemination of big data (BD) has brought a new dimension to the value of data applications. The combination of BD and youth health services provides young people with good health opportunities. Through the recording, analysis and release of adolescent physical health data, the system has established an extensive knowledge database on adolescent physical and mental health, thus improving the physical health of adolescents. This paper summarized and combed the overview and application of BD, and analyzed and discussed the reasons for the continuous decline of young people's physique. Through the analysis of the application of BD in the promotion of young people's physical health, this paper proposed more achievable improvement strategies and plans, and then summarizes and discusses the experiment. According to the survey and experiment, the random simulation algorithm was introduced into daily exercise, diet and life preference. The new system and health improvement strategy designed for teenagers’ physical health using BD could help students improve their physical health by 55%.

Longitudinal changes in cardiorespiratory fitness among firefighters based on a fixed 12.0 MET standard and an age-adjusted fitness standard.

Firefighting is a physically demanding profession. Firefighters (FFs) need adequate physical fitness (PF) to perform duty tasks efficiently. While FFs' work demands are constant throughout their career, there is an expected age-related decline in PF. To describe longitudinal changes in cardiorespiratory fitness (CRF) based on a fixed (12.0 METs) and an age-adjusted standard and compare the prevalence of fit/unfit firefighters (FFs) over eight years. 297 Brazilian male firefighters were randomly selected. CRF was assessed by the 12-minute Cooper test. To compare the prevalence's of fit/unfit FFs depending on the standard (12 METs vs. age-adjusted), the McNemar test was used. The reduction in the prevalence of fit firefighters was 4.4-fold higher when the analysis did not consider age. After eight years, the prevalence of fit FFs decreased by 30.5% based on the fixed standard, while this reduction was only 7% when using an age-adjusted standard.