In oncology settings, music, especially music therapy (MT), is frequently used to improve patients' quality of life, pain situation, anxiety, depression, fatigue, and comfort. However, to date, there are no prospectively collected data correlating regular standardized MT sessions during radiotherapy (RT) to physical parameters such as heart rate, blood pressure, respiratory rate, and oxygen saturation and corresponding quality of life measures using quantitative descriptive scales in oncological patients. Thus, the aim of this study was to investigate the effect of MT on the condition of radiooncology patients using these parameters. During this study, patients participated weekly MT sessions guided by aboard-certified music therapist. Data such as pain, physical comfort, and respiratory comfort based on the visual analogue scale (VAS) were collected before and after MT sessions. Furthermore, vital signs including heart rate, blood pressure, respiratory rate, and oxygen saturation as well as RT side effects were recorded. A total of 57patients (age 61 ± 11years) were enrolled in the study. Median VAS score was significantly different before and after MT for pain: VAS1 (interquartile range [IQR]: 0-3) vs. VAS0 (IQR: 0-2; p < 0.001); physical comfort: VAS7 (IQR: 6-7) vs. VAS8 (IQR: 7-9; p < 0.001); and respiratory comfort only in the patients with pre-existing symptoms (VAS < 10 before therapy): VAS8 (IQR: 6-8) vs. VAS9 (IQR: 8-10; p = 0.002). Furthermore, vital signs were significantly reduced from pre-session to post-session (p > 0.001): heart rate 81 ± 14 min-1 to 76 ± 13 min-1 and respiratory rate from 12 ± 5 min-1 to 10 ± 4 min-1. RT-related side effects did not interfere with participation in MT sessions. In our study cohort of radiooncology patients, weekly MT sessions improved defined physical parameters as well as pain, physical comfort, and respiratory comfort. Establishing MT in the routine clinical setting should be more readily considered to further improve patient outcomes.
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