Photomultiplier Detector Research Articles

An end-to-end calibration of the Mini-EUSO detector in space

Mini-EUSO is a wide Field-of-View (44∘×44∘) telescope currently in operation from a nadir-facing Ultra-Violet (UV) transparent window in the Russian Zvezda module on the International Space Station (ISS). Mini-EUSO has been designed as a scaled-down version of the original JEM-EUSO telescope to raise its instrumentation’s technological readiness level and demonstrate its observational principle, while performing multidisciplinary studies on different fields such as atmospheric science and planetology. One of Mini-EUSO main goals is the study of the UV background for future space missions employing the same concept as the original JEM-EUSO telescope, which requires an absolute calibration of the Mini-EUSO instrument. During the past years, a few observational campaigns have been completed, employing a ground-based UV flasher to perform an end-to-end calibration of the instrument. In this paper, we present the assembled UV flasher system, the operation of the field campaign and the analysis of the obtained data. The results are interpreted by the means of a parametrization of the Mini-EUSO photon counts. The end-to-end efficiency of several pixels has been obtained, taking into account different parameters such as the atmospheric attenuation, the optics efficiency and the multi-anode photomultiplier detection efficiency.

Light Scattering Measurements of KCl Particles as an Exoplanet Cloud Analog

Salt clouds are predicted to be common on warm exoplanets, but their optical properties are uncertain. The Exoplanet Cloud Ensemble Scattering System (ExCESS), a new apparatus to measure the scattering intensity and degree of linear polarization for an ensemble of particles, is introduced here and used to study the light scattering properties of KCl cloud analogs. ExCESS illuminates particles with a polarized laser beam (532 nm) and uses a photomultiplier tube detector to sweep the plane of illumination. Scattering measurements for KCl particles were collected for three size distributions representative of modeled clouds for the warm exoplanet GJ 1214b. Our measurements show that Lorenz–Mie calculations, commonly used to estimate the light scattering properties of assumedly spherical cloud particles, offer an inaccurate depiction of cubic and cuboid KCl particles. All of our measurements indicate that Lorenz–Mie scattering overestimates the backscattering intensity of our cloud analogs and incorrectly predicts the scattering at mid-phase angles (∼90°) and the preferential polarization state of KCl scattered light. Our results align with the general scattering properties of nonspherical particles and underscore the importance of further understanding the effects that such particles will have on radiative transfer models of exoplanet atmospheres and reflected light observations of exoplanets by the upcoming Nancy Grace Roman Space Telescope and Habitable Worlds Observatory.

Hybrid FDG-PET/MRI for Diagnosis and Clinical Management of Patients with Suspected Perihilar Cholangiocarcinoma: A Feasibility Pilot Study

PurposeRecently introduced hybrid 2-[18 F]-fluoro-2-deoxy-D-glucose (18 F-FDG) Positron Emission Tomography (PET) combined with Magnetic Resonance Imaging (MRI) may aid in proper diagnosis and staging of perihilar cholangiocarcinoma (pCCA). The aim of this study is to assess the effect of 18 F-FDG PET/MRI on diagnosis and clinical decision making in the pre-operative work up of pCCA.MethodsIn this single-centre pilot study patients with presumed resectable pCCA underwent state-of-the-art 18 F-FDG hybrid PET/MRI using digital silicone photomultiplier detectors integrated within a 3-Tesla bore. Data were collected on several baseline and imaging characteristics. The primary outcome measure was the added diagnostic information and the effect on clinical decision making. Secondary aim was to correlate quantitative PET signal intensity to patient- and tumour characteristics. High and low SUVmax subgroups related to the mean value were made. Significance of lesion- and patient characteristics with the high and low SUVmax subgroups, as well as TLR and TBR, was evaluated with Fisher’s exact test or Mann-Whitney-U test.ResultsIn total 14 patients were included (mean age 62.4 years, 64% male). Final diagnosis was pCCA in 10 patients (71.4%), follicular lymphoma in one patient (7.1%) and benign disease in the remaining three patients. FDG-PET/MRI added valuable diagnostic information in six (43%) patients and affected clinical decision making in two of these patients (14%) by increasing confidence for malignancy which lead to the decision for surgery on short term. High SUVmax values were seen in half of cases with pCCA and half of cases with non-cancerous lesions. In addition, high SUVmax values were directly associated with primary sclerosing cholangitis when present (p = 0.03).ConclusionSimultaneous 18 F-FDG-PET/MRI added diagnostic information in six of fourteen patients and influenced clinical decision making in two patients (14%) with presumed resectable pCCA.

High throughput compressive fluorescence lifetime imaging with a silicon photomultiplier detector.

Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique for studying biological processes. There exists a growing interest in developing strategies to enhance throughput and reduce acquisition time of FLIM systems, which commonly employ laser scanning excitation and time-correlated single-photon counting (TCSPC) detection. In this work, we propose a wide-field FLIM microscope based on compressive sensing and high photon rate detection (beyond pile-up limit) based on a high-efficiency silicon photomultiplier detector as a single-pixel camera. We experimentally validate the capabilities of this design achieving 20 frames per second FLIM images on free-moving green algae sample.

Transformer-CNN hybrid network for improving PET time of flight prediction

Objective. In positron emission tomography (PET) reconstruction, the integration of time-of-flight (TOF) information, known as TOF-PET, has been a major research focus. Compared to traditional reconstruction methods, the introduction of TOF enhances the signal-to-noise ratio of images. Precision in TOF is measured by full width at half maximum (FWHM) and the offset from ground truth, referred to as coincidence time resolution (CTR) and bias. Approach. This study proposes a network combining transformer and convolutional neural network (CNN) to utilize TOF information from detector waveforms, using event waveform pairs as inputs. This approach integrates the global self-attention mechanism of Transformer, which focuses on temporal relationships, with the local receptive field of CNN. The combination of global and local information allows the network to assign greater weight to the rising edges of waveforms, thereby extracting valuable temporal information for precise TOF predictions. Experiments were conducted using lutetium yttrium oxyorthosilicate (LYSO) scintillators and silicon photomultiplier (SiPM) detectors. The network was trained and tested using the waveform datasets after cropping. Main results. Compared to the constant fraction discriminator (CFD), CNN, CNN with attention, long short-term memory (LSTM) and Transformer, our network achieved an average CTR of 189 ps, reducing it by 82 ps (more than 30%), 13 ps (6.4%), 12 ps (6.0%), 16 ps (7.8%) and 9 ps (4.6%), respectively. Additionally, a reduction of 10.3, 8.7, 6.7 and 4 ps in average bias was achieved compared to CNN, CNN with attention, LSTM and Transformer. Significance. This work demonstrates the potential of applying the Transformer for PET TOF estimation using real experimental data. Through the integration of both CNN and Transformer with local and global attention, it achieves optimal performance, thereby presenting a novel direction for future research in this field.

Experimental study of plastic scintillators array for compact fast neutron-gamma dual-modality imaging system

In a compact multi-radiation imaging system, the substitution of traditional charge-coupled devices with a plastic scintillators array coupled with silicon photomultiplier detectors significantly enhances the radiation tolerance of the detection and imaging module, thereby reducing the system footprint. We present a detailed structure of a compact fast neutron/gamma-ray dual-modality imaging system based on a plastic scintillators array and evaluate its performance in imaging various samples. The detector array consists of nine 14.7 × 14.7 × 100 mm3 EJ-276 plastic scintillators coupled with corresponding silicon photomultiplier units, arranged in a 3 × 3 grid. The usage of EJ-276 plastic scintillators allows for discrimination between neutron and gamma signals through pulse shape discrimination techniques, enabling data separation between neutrons and gamma rays. In this paper, we present the experimental procedure and results of fast neutron-gamma imaging for objects containing aluminum and polyethylene materials. Fast neutrons and gammas are delivered by an Cf-252 source. The experimental results demonstrate that the system achieves dual-modality grayscale imaging and has resolution for sample thickness. Reconstructed image contrast allows qualitative differentiation of sample materials, especially detecting low-Z materials encapsulated by high-Z materials.

Development and Study of Magnetic Shields for Neutrino Detector Photomultiplier Tubes under Neutrino-4M Experiment on PIK and SM-3 Reactors

Development and Study of Magnetic Shields for Neutrino Detector Photomultiplier Tubes under Neutrino-4M Experiment on PIK and SM-3 Reactors

Electronics and Detectors for the Stellar Intensity Interferometer of the ASTRI Mini-Array Telescopes.

The ASTRI Mini-Array is an international collaboration led by the Italian National Institute for Astrophysics (INAF) that will operate nine telescopes to perform Cherenkov and optical stellar intensity interferometry (SII) observations. At the focal plane of these telescopes, we are planning to install a stellar intensity interferometry instrument. Here we present the selected design, based on Silicon Photomultiplier (SiPM) detectors matching the telescope point spread function together with dedicated front-end electronics.

Auto-Lectin Dotcoding by Two Octopuses: Rapid Analysis of Fluorescence-Labeled Glycoproteins by an 8-channel Fully-Automatic Bead Array Scanner with a Rolling-Circle Detector.

Protein glycosylation is a crucial factor that must be evaluated in biological pharmaceuticals. The glycoform profile of a protein can vary depending on the conditions of the cultivation, purification process, and the selection of a host cell. Lectin microarrays are reliable bioanalytical methods used in the early phases of bioprocesses for the detection of glycosylation. The concept of a fully automated glycan detection with a bead array has been previously reported; however, no simple system has been constructed on fluorescence-based detection using a microarray. Here, we present a fully automated detection system equipped with a novel fluorescence detector for a 13-lectin bead array with a single tip. The lattice-like arrangement of a set of fibers proximate to the tip of the light emitting diode and photomultiplier tube detector minimized the noise caused by the reflection of incident light on the plastic capillary tip and bead. A unique rolling-circle fiber unit with quadruple lattices stacked in two layers realizes the 8-parallel automeasurement with a drastic reduction in scanning time and machine size. The 8-glycan profiles obtained automatically within 25 min were identical with those obtained with the conventional lectin microarray after overnight incubation. The signals obtained were represented as lectin dotcodes. Therefore, autolectin dotcoding assisted by the twin 8 legs named as "detection and irradiation octopuses" may be a rapid glyco-evaluation system during the production and development of biopharmaceuticals.

An extendable optical fibre probe survey meter for naturally occurring radioactive material (NORM) and other weak emitters

We have developed a radioluminescence-based survey meter for use in industries in which there is involvement in naturally occurring radioactive material (NORM), also in support of those needing to detect other weak emitters of radiation. The functionality of the system confronts particular shortcomings of the handheld survey meters that are currently being made use of. The device couples a LYSO:Ce scintillator with a photodetector via a polymer optical fibre waveguide, allowing for "intrinsically safe" inspection within pipework, separators, valves and other such component pieces. The small-diameter optical fibre probe is electrically passive, immune to electromagnetic interference, and chemically inert. The readout circuit is entirely incorporated within a handheld casing housing a silicon photomultiplier (SiPM) detection circuit and a microprocessor circuit connected to an LCD display. A 15 m long flexible PMMA optical fibre waveguide is butt coupled to an ABS plastic probe that retains the LYSO:Ce scintillator. Initial tests have included the use of lab-based mixed gamma-ray sources, measurements being made in concert with a reference conventional GM survey-meter. Characterization, via NORM sources at a decontamination facility, has shown useful sensitivity, covering the dose-rate range 0.10- to 28 µSv h−1 (R-squared 0.966), extending to 80 µSv/h as demonstrated in use of a Cs-137 source. The system is shown to provide an effective tool for detection of radioactivity within hard to access locations, in particular for sources emitting at low radiation levels, down to values that approach background.

Photomultiplier characterisation and its impact on background for SABRE South

SABRE (Sodium iodide with Active Background REjection) South is a NaI(Tl) based dark matter direct detection experiment located at the Stawell Underground Physics Laboratory (SUPL) [J. Phys. Conf. Ser. 2156, 012064 (2021), arXiv:2205.13849]. It is designed to detect an annual modulation of WIMP recoils as an independent replication of the long-standing DAMA/LIBRA modulation signal. SABRE South will have a low energy threshold of 1 keV in the NaI(Tl) crystal detector and a low experimental background. This requires precise characterisation of the photomultipliers used to understand both their sensitivity at low thresholds and their contribution to the background. We report on the photomultiplier characterisation test bench developed for the crystal detector photomultipliers including studies of the single photon response, transit time, and dark noise. A specific focus is on estimating the contribution to the experimental background of coincident photomultiplier noise due to its predominance at low energy and inability to be modelled using traditional MC simulation.

Measurement system for ultraviolet channel modeling and communications.

There has been an increasing interest in ultraviolet (UV) communications as a promising technology for non-line-of-sight (NLOS) networking by exploiting atmospheric scattering at UV wavelengths that enables a unique NLOS UV communication channel. While there has been significant theoretical and simulation-based investigation of the UV channel characteristics, there is limited work in terms of experimental research and validation of the analytical models. In this paper, we present a flexible experimental system for precise UV channel and communications measurements. Specifically, a transceiver system is developed that consists of a gimbal, UV light-emitting-diode array, and photomultiplier tube detector, node synchronization, and LabVIEW-based data acquisition subsystems. Novel techniques to precisely characterize the UV LED array radiation pattern, absolute transmit power, and field of view of the detector are also presented. The utility of the developed system is then demonstrated by performing a variety of experiments including UV channel model validation and steering optimization for UV communication links where the results were in very good agreement with theory and simulation.

Early detection and warning of standoff bio-threats using ultraviolet laser wavelengths

The paper presents the results of detection experiments conducted to detect bio-aerosol from a standoff distance of nearly 2 km using laser scattering and ultraviolet laser induced fluorescence (UV-LIF) LiDAR in the presence of potential interfering molecules (molecules having spectrum overlapping with the biological warfare agents). The presence of interfering molecules can make the detection of bio-aerosol difficult. Therefore, conduction of detection experiments in the presence of interfering molecules is a must to develop a system such as to keep the false signal at bay. The software for synchronized spectrum acquisition (gated mode) of UV-LIF signatures of bio-aerosol has been developed and integrated into the system. The detection algorithm on data discrimination has been implemented. Standoff experiments using the developed software have been carried out with the samples consisting of bio-aerosols and interfering molecules. The wavelengths used in the experiments are 266 and 355 nm as the fluorescence quantum yield of two prominent bio-markers is high at these excitation wavelengths. Spectra were acquired with the developed system and analyzed by the developed software. The bio-agents were detected and discriminated from the interfering molecules successfully. In addition to this, the scattering method is also utilized to make distinction between bio and non-bio-molecules using two identical photomultiplier tube detectors based on the depolarization method.

Scalable, modular continuous wave functional near-infrared spectroscopy system (Spotlight).

We present a fiberless, portable, and modular continuous wave-functional near-infrared spectroscopy system, Spotlight, consisting of multiple palm-sized modules-each containing high-density light-emitting diode and silicon photomultiplier detector arrays embedded in a flexible membrane that facilitates optode coupling to scalp curvature. Spotlight's goal is to be a more portable, accessible, and powerful functional near-infrared spectroscopy (fNIRS) device for neuroscience and brain-computer interface (BCI) applications. We hope that the Spotlight designs we share here can spur more advances in fNIRS technology and better enable future non-invasive neuroscience and BCI research. We report sensor characteristics in system validation on phantoms and motor cortical hemodynamic responses in a human finger-tapping experiment, where subjects wore custom 3D-printed caps with two sensor modules. The task conditions can be decoded offline with a median accuracy of 69.6%, reaching 94.7% for the best subject, and at a comparable accuracy in real time for a subset of subjects. We quantified how well the custom caps fitted to each subject and observed that better fit leads to more observed task-dependent hemodynamic response and better decoding accuracy. The advances presented here should serve to make fNIRS more accessible for BCI applications.

How Fast is Your Detector? The Effect of Temporal Response on Image Quality.

With increasing interest in high-speed imaging, there should be an increased interest in the response times of our scanning transmission electron microscope detectors. Previous works have highlighted and contrasted the performance of various detectors for quantitative compositional or structural studies, but here, we shift the focus to detector temporal response, and the effect this has on captured images. The rise and decay times of eight detectors' single-electron response are reported, as well as measurements of their flatness, roundness, smoothness, and ellipticity. We develop and apply a methodology for incorporating the temporal detector response into simulations, showing that a loss of resolution is apparent in both the images and their Fourier transforms. We conclude that the solid-state detector outperforms the photomultiplier tube-based detectors in all areas bar a slightly less elliptical central hole and is likely the best detector to use for the majority of applications. However, using the tools introduced here, we encourage users to effectively evaluate which detector is most suitable for their experimental needs.

Infrared laser ablation dynamics using light scattering

The dynamics of infrared laser ablation at atmospheric pressure was studied employing continuous visible laser light scattering in the expanding plume. A pulsed infrared optical parametric oscillator at 2940 nm wavelength and 5 ns pulse width was used to irradiate samples comprising liquid glycerol or 50 µm thick sections of rat liver tissue. The scattered light from the expanding laser ablation plume was measured using a 532 nm continuous laser parallel to the target and several millimeters above the ablated spot. The scattered light was recorded using a photomultiplier detector and the signal used to estimate the time at which the plume front passed through the continuous laser beam. The velocity of the ablation plume was obtained from consecutive time and distance measurements and the fraction of the laser energy transferred to the expanding shock wave was determined using the Taylor shock wave model. Plume modeling calculations indicate that the ablation is driven by phase explosion that is thermally confined and near the stress confinement regime.

ArduSiPM technology: Compact and light All-in-one detectors for space application

ArduSiPM technology integrates System on Chip (SoC) innovation and Silicon photomultiplier (SiPM) detector improvements into a new generation of all-in-one scintillation detectors, developed by INFN Rome since 2014. To minimize reliance on pre-built Commercial off-the-shelf (COTS) components, we utilize the peripherals and CPU of the SoC for edge computing tasks and various functions, such as Counters, Analog-to-Digital Converters (ADCs), Digital-to-Analog Converters (DACs), Pulse-Width modulation (PWM), and digital input/output interfaces. Our compact electronic system eliminates the need for external data acquisition systems and ASICs, while also enabling the CPU to perform edge computing functions. The detector, capable of measuring the rate, arrival time (with a resolution of 7 ns correlated to the SoC main clock), and number of photons arriving on the SiPM, is ideal for radiation monitoring and highly sensitive photon detection. The INFN MICRO experiment explores circuits and engineering solutions for developing detectors for diverse fields such as Transient Luminous Events, analytical chemistry, and nano/picosatellites. Our ultimate goal is to integrate the detector into the onboard computer of a satellite, akin to navigation instruments and attitude control systems, with future improvements in SoC technology easily leveraged thanks to our approach’s independence from the specific SoC.

A SiPM-Based Gamma Spectrometer With Field-Programmable Energy Binning for Data-Efficient Isotope Analysis

A highly reconfigurable gamma spectrometer with a silicon photomultiplier detector and a custom integrated circuit (IC)-based multi-channel analyzer (MCA) is presented. The core of the MCA comprises a custom analog front-end IC and a piecewise-linear analog-to-digital converter (ADC) IC, both fabricated in a 180nm complementary metal-oxide-semiconductor (CMOS) process. Along with a field-programmable gate array (FPGA)-based digital back-end, the proposed architecture allows pulse-height analysis with reconfigurable analog gain and ADC resolution across the full dynamic range. Specifically, the piecewise-linear ADC can increase resolution in selected regions of interest while utilizing a fixed 7-bit digital word, thus enabling data reduction and spectrum feature enhancement. Reconfigurability also allows the MCA to be tuned for different scintillator materials used in the detector. The system architecture is introduced at a conceptual level, followed by detector and circuit-level MCA implementation details and design trade-offs. Several isotope spectra were recorded with two common scintillators, LYSO and CsI(Tl), spanning energy peaks from 32keV to 1.33MeV. Variable energy bin-widths were measured across different AFE gains, ranging from 3keV to 58keV for LYSO, and 1.4keV to 51keV for CsI(Tl), demonstrating the versatility of the proposed system and its ability to provide reconfigurable peak enhancement for radiation spectroscopy.

Gamma Scientific Sets High Standards for Light Measurement

Gamma Scientific Sets High Standards for Light Measurement

High-performance UV-Vis-NIR photomultiplier detectors assisted by interfacial trapped-electrons

A photomultiplication-type YZ-PD with excellent photodetection performance in the UV–Vis–NIR region was successfully constructed using a bulk heterojunction strategy.