Phenoxide Nucleophiles Research Articles

Studies on ristocetin A. A synthesis of protected ristomycinic acid using organomanganese chemistry.

Aryl ether formation by reaction of phenoxide nucleophiles with chloroarene-Mn(CO) 3 cationic complexes, followed by reaction of the aryloxyarene-Mn(CO) 3 complex with chiral glycine enolate equivalents, provides methodology for the synthesis of protected ristomycinic acid derivatives in a state of high optical purity.

Studies on selective nucleophilic substitution reactions of [(cyclopentadienyl)(1,3-dichlorobenzene)M]+ PF6- complexes (M = iron, ruthenium)

Reactions of [cyclopentadienyl)(1,3-dichlorobenzene)M] + PF 6 - complexes (M= Fe, Ru) with phenoxide nucleophiles were found to proceed with excellent selectivity under mild conditions to give products of monosubstitution. Using aminophenoxides, a preference for O-arylation was observed, while amino alcohols such as prolinol react selectively on nitrogen. Methodology for sequential selective displacement of both chlorides by different nucleophiles is reported

ChemInform Abstract: SYNTHESIS OF 5‐(SUBSTITUTED METHYL)‐6,8‐DIMETHYL‐4‐CHROMANONES

AbstractUmsetzen der Chromanone (I) mit verschiedenen nucleophilen Reagenzien liefert die Titelverbindungen (II), (IV), (VI) und (VIII).

Synthesis of 5-(Substituted methyl)-6,8-dimethyl-4-chromanones

Abstract 5-(Substituted methyl)-6,8-dimethyl-4-chromanones were synthesized from the reactions of 5-hydroxymethyl-6,8-dimethyl-4-chromanone with nucleophilic reagents in acid media, and the reactions of its 5-halomethyl derivatives with ethoxide or phenoxide nucleophiles.