Pharyngeal Pain Research Articles

LMA-ProSeal insertion by novice doctors as affected by a 90° bend created by an intubating stylet: a randomized clinical trial

Study ObjectiveThis study aimed to test the hypothesis that insertion of the supraglottic device LMA-ProSeal (ProSeal) by novice doctors in anesthetized patients can be improved by using an intubating stylet to create a 90° bend and that better sealing pressure is achieved. DesignRandomized clinical trial. SettingOperating room. PatientsSeventy adult patients scheduled for elective surgery under general anesthesia using ProSeal with American Society of Anesthesiologists physical status 1 to 3. InterventionsProSeal were inserted with the 90° bend created by the intubating stylet (90D group, 35 patients) or not (ie, conventional insertion; C group, 35 patients). MeasurementsThe number of attempts to successful insertion, sealing pressure, subjective difficulty of insertion by novice doctors, and postoperative pharyngeal pain or hoarseness were compared between groups. Main ResultsThe total number of insertion attempts for the 90D and control groups were 1 (24 and 8, respectively), 2 (8 and 13), 3 (3 and 9), and failure (0 and 5), respectively, showing significant differences between groups (P<.001). Sealing pressure was significantly higher in the 90D group than in the C group (90D group, 23.3±3.7cm H2O; C group, 19.5±2.6cm H2O; P<.001), and the subjective difficulty of insertion was significantly lower in the 90D group (90D group, 27.3±17.6mm; C group, 55.4±22.8mm; P<.001). The incidence of postoperative pharyngeal pain and hoarseness did not differ significantly between groups. ConclusionsOur results suggest that creating a 90° bend using an intubating stylet facilitates ProSeal insertion by novice doctors, as reflected by higher successful insertion rates, higher sealing pressure, and lower subjective difficulty of insertion in anesthetized patients.

Managing Pharyngeal and Oral Mucosal Pain

Oropharyngeal pain is a common chief complaint in the emergency department and primary care offices. Etiologies include pharyngitis from viral or bacterial infections, tonsillitis, oral mucositis from chemotherapeutic agents, infections such as the herpes simplex virus, aphthous stomatitis and dental pain from abscesses, decay and post-extractions. Patients present for evaluation of their disease, but importantly, patients also seek pain control. This review focuses on pain management of the simple acute sore throat, dental pain, and oral mucosal pain. Common medications such as acetaminophen, non-steroidal anti-inflammatory agents (NSAIDS), corticosteroids, topical agents, and natural agents may be utilized for oropharyngeal and dental discomfort. With the exception of two societies that recommend NSAIDs and acetaminophen as first line medications for managing pain from acute pharyngitis, no other guidelines or useful recommendations are currently available. Thus, while this review does discuss several options for pain control, it will be up to the clinician to weigh the benefits and drawbacks of the medications and find the right one for each patient and his or her condition.

Esophageal Intramural Abscess from Injury in an Adult

A 33-year-old man with diabetes was referred to our hospital with the complaints of retrosternal pain, pharyngeal pain and high fever up to 39°C. He had history of fish bone ingestion 2 weeks previously. Examination of the heart and lungs was normal, and there were no apparent enlarged lymph nodes. The tumor markers were all within neutrophils. Subsequent chest contrast-enhanced CT showed diffuse thickening of esophageal wall in the middle and lower part, associated with inner low density similar to fluid. There were large quantities of gas retention in the lumen of esophagus, which suggested disorder of esophageal peristalsis in this region. Minimal effusion was also noticed in both pleural cavit. In combination with different data from this patient, esophageal abscess was first proposed. The patient accepted conservative treatment including nothing by mouth, broadspectrum antibiotics and intravenous fluid support for ten days. The patient’s symptoms improved significantly and his temperature recovered to be normal level. Follow-up CT revealed the disappearance of low attenuation within thickening esophageal wall and endoluminal air.

Bevacizumab plus cisplatin and helical tomotherapy in treatment of locally advanced nasopharyngeal carcinoma.

BackgroundIn recent years, chemotherapy, radiotherapy, and targeted drugs have been respectively used in nasopharyngeal carcinoma. In our research, we combined all of them for better curative effects.Materials and methodsThirty patients with histologically confirmed stage III~IV (without distant metastasis) nasopharyngeal carcinoma were recruited between December 2013 and October 2014 with strict eligibility requirements and exclusion criteria. Bevacizumab 5 mg/kg, 80 mg/m2 cisplatin and 67.5 Gy radiotherapy (helical tomotherapy [TOMO]) was given according to standard treatment protocols.ResultsAfter 3 months, 24 complete responses (80%) and six partial responses (40%) were observed in our research. Twenty-four patients (80%) experienced oropharyngeal mucositis, 26% patients experienced weight loss caused by pharyngeal pain and dysphagia caused by oropharyngeal mucositis.ConclusionBevacizumab plus cisplatin and TOMO in treatment of locally advanced nasopharyngeal carcinoma can increase curative effects with low side effects and toxicities.

Clinical observation on treating reflux esophagitis of deficiency of spleen Qi syndrome byHezhong-Jianpi decoction

Objective To observe the clinical curative effect of treating reflux esophagitis of spleen qi deficiency syndrome by Hezhong-Jianpi decoction. Methods 90 patients in October 2012 to March 2014 in the standard of traditional Chinese medicine hospital of Shanghai were randomly divided into a western medicine group (omeprazole), a Chinese medicine group (Hezhong-Jianpi decoction), and a Chinese and western medicine group (Hezhong-Jianpi decoction + omeprazole), 30 cases in each group. All groups were treated for successive 8 weeks and the changes of the symptoms of integral and esophageal mucosa under gastroscope change situation were observed, and the clinical efficacy was evaluated. Results After the treatment, the esophagus gastroscope integral of the western medicine group, the Chinese medicine group and the Chinese and western medicine group were all significantly improved than those before the treatment group (Z value was respectively -4.351, -4.300, -5.143, P<0.01). Total effective rate was 83.3% (25/30) in the western medicine group, 86.7% (26/30) in the Chinese medicine group, and 90.0% (27/30) in the Chinese and western medicine group, the difference among the three groups was statistically significant (χ2=6.800, P=0.030). The difference of symptoms integral of the western medicine, Chinese medicine, and Chinese and western medicine group was statistically significant (Z values are -5.482, -5.991, -6.120, respectively, P<0.01).Comparison between two groups after treatment showed only Chinese traditional medicine group and the Chinese and western medicine group was statistically significant (Z=-2.113, P=0.040). After the treatment, symptoms as heartburn (Z value -3.390, -3.882, -3.666, respectively), the acid regurgitation (Z value -4.850, -5.004, -5.722, respectively), the food regurgitation (Z value -2.791, -3.422, -2.854, respectively) in the three groups improved significantly than those before the treatment (P<0.01); The retrosternal pain improved significantly in the Chinese and western medicine group after the treatment (Z=-0.873, P=0.380). The pharyngeal foreign body sensation or pain symptoms (Z value were -2.382 and -2.724, respectively), belching symptoms (Z value were -5.074 and -5.061, respectively) in the Chinese traditional medicine group and the Chinese and western medicine group significantly improved after the treatment(P<0.05); The abdominal distension (Z value were 2.772 and -2.032, respectively), the abdominal pain (Z value were 2.26 and 2.02, respectively) in the western medicine group and the Chinese and western medicine group were significantly improved (P<0.05). Conclusion Hezhong-Jianpi decoction can significantly improve the clinical symptoms of reflux esophagitis of spleen qi deficiency, and the curative effect is similar to omeprazole. It has advantage for relieving belch and retrosternal pain. The combined therapy was more effective than either Hezhong-Jianpi or omeprazole, but no difference was showed in the improvement of esophageal gastroscopy. Key words: Esophagitis, peptic; Hezhong-Jianpi decoction; Omeprazole; Treatment outcome

The first case of human infestation with Linguatula serrata in Kermanshah province

Linguatula serrata is a cosmopolitan organism belonging to the Phylum Pentastomida. Humans may act as an intermediate (Halzoun syndrome) or accidental definitive host of this parasite, manifesting the nasopharyngeal or visceral form. Linguatulosis occurs accidentally in human by ingestion of raw or undercooked visceral tissues of sheep, goat, camel, and other herbivores. This is the first report of Halzoun syndrome in Kermanshah province. In this case report, a 34-year-old man, from Salas-o-babajani district infested with this parasite was presented. Clinical signs and symptoms included pricking sensation in throat, coughing, sneezing and nasal discharge, which started 2-3 hours after eating undercooked goat liver. An organism in about 8 mm length was isolated from his pharyngeal discharge. The sample was examined in the pparasitology llaboratory of Kermanshah school of medicine. The results of analysis showed that this organism was the nymph of L. The serrata had a mouth surrounded by four hooks and a segmented body with small hooks. The patient was treated using oral anti histamines and gargling and nasal washing with saline solution. So, it is recommended that physicians consider L. Serrata infestation in patients with complaints such as pharyngitis accompanied by pharyngeal pain, coughing, sneezing and vomiting.

Laryngoscopy facilitates successful i-gel insertion by novice doctors: a prospective randomized controlled trial

This study investigated the hypothesis that the efficacy of insertion of the supraglottic device i-gel(®) (i-gel) can be improved by laryngoscopy and can provide better sealing pressure in anesthetized patients by novice doctors. Eighty-four adult patients were assigned to the laryngoscopy group (L group, 42 patients) or control group (i.e., conventional blind insertion; C group, 42 patients). Anesthesia was induced with propofol and remifentanil, and rocuronium 0.6-0.9 mg/kg was administered. The number of attempts until successful insertion, sealing pressure, vital sign changes upon insertion, and subjective difficulty of insertion by novice doctors were compared between the groups. The total number of insertion attempts was one (L group 36 cases, C group 23 cases), two (L group 6 cases, C group 18 cases), and three (L group 0 case, C group 1 case), with significant differences between groups (P = 0.007). The sealing pressure was significantly higher in the L group than in the C group (L group 22.3 ± 2.6 cmH2O, C group 19.5 ± 2.7 cmH2O, P < 0.001). Vital sign changes (heart rate and blood pressure) did not differ between the two groups. The subjective difficulty of insertion was significantly lower in the L group than in the C group (L group 26.8 ± 11.8 mm, C group 47.0 ± 15.1 mm, P < 0.001). The incidence of postoperative pharyngeal pain was significantly lower in the L group than in the C group (P < 0.001), while the incidence of hoarseness did not differ between the two groups (P = 1.00). Our results suggest that laryngoscopy facilitates i-gel insertion by novice doctors, as reflected in the rate of successful insertions, higher sealing pressure, and lower subjective difficulty of insertion in anesthetized patients.

Disorders of the lower cranial nerves.

Lesions of the lower cranial nerves (LCN) are due to numerous causes, which need to be differentiated to optimize management and outcome. This review aims at summarizing and discussing diseases affecting LCN. Review of publications dealing with disorders of the LCN in humans. Affection of multiple LCN is much more frequent than the affection of a single LCN. LCN may be affected solely or together with more proximal cranial nerves, with central nervous system disease, or with nonneurological disorders. LCN lesions have to be suspected if there are typical symptoms or signs attributable to a LCN. Causes of LCN lesions can be classified as genetic, vascular, traumatic, iatrogenic, infectious, immunologic, metabolic, nutritional, degenerative, or neoplastic. Treatment of LCN lesions depends on the underlying cause. An effective treatment is available in the majority of the cases, but a prerequisite for complete recovery is the prompt and correct diagnosis. LCN lesions need to be considered in case of disturbed speech, swallowing, coughing, deglutition, sensory functions, taste, or autonomic functions, neuralgic pain, dysphagia, head, pharyngeal, or neck pain, cardiac or gastrointestinal compromise, or weakness of the trapezius, sternocleidomastoid, or the tongue muscles. To correctly assess manifestations of LCN lesions, precise knowledge of the anatomy and physiology of the area is required.

Tinnitus Associated with Eagle Syndrome: A Case Report

Introduction: Eagle syndrome is a condition characterized by elongated styloid process or calcification of the stylohyoid ligament associated with cervicofacial painful symptoms. Incidence varies from 4 to 28% prevailing in adult women. The classic syndrome leads to pharyngeal pain and earache, relating to healing after tonsillectomy or cervical trauma. The syndrome styloid apophysis with carotid artery involves compression of the carotid arteries, predominantly dysphagia, earache, and headache, with few reported symptoms such as dizziness and tinnitus. The diagnosis is clinical and radiographic. Treatment may be conservative or surgical. However, the most effective is surgical resection of the styloid apophysis.

Hypopharyngeal Airway Surgery for Obstructive Sleep Apnea: Morbidity in the Early Postoperative Period

Objectives: Determine if hypopharyngeal surgery for obstructive sleep apnea is associated with significant morbidity in the early postoperative period. Methods: Medical records review and retrospective telephone survey of patients who underwent hypopharyngeal surgery for obstructive sleep apnea between November 2012 and September 2013 at a tertiary care facility. Results: Twenty-two patients underwent hypopharyngeal surgery for obstructive sleep apnea. No patient experienced intraoperative complications, postoperative O2 desaturation &lt;90%, prolonged admission for inadequate pain control, pulmonary edema, or airway compromise requiring re-intubation. Postoperative complications included 1 episode of nasal hemorrhage, 1 infection requiring hospitalization, and 1 episode of dehydration treated with IV fluids. Twenty-five percent of patients experienced some degree of postoperative dysphonia, and 87.5% of patients experienced postoperative dysphagia. The average rating for postoperative pharyngeal pain was 3.5 by week 3 and 1.75 by week 4. Most patients described decreased snoring (93.75%), improved feeling of overall health (75%), and increased daytime energy (62.5%). All patients undergoing hypopharyngeal airway surgery were discharged within 23 hours. Conclusions: Hypopharyngeal surgery is a safe and well-tolerated procedure for the treatment of OSA. Our findings suggest that hypopharyngeal surgery may be performed on an outpatient basis.

Chemistry and pharmacology of Siraitia grosvenorii: A review

Siraitia grosvenorii is a perennial herb endemic to Guangxi province of China. Its fruit, commonly known as Luo hanguo, and has been used for hundreds of years as a natural sweetener and as a traditional medicine for the treatment of pharyngitis, pharyngeal pain, as well as an anti-tussive remedy in China. Based on ninety-three literary sources, this review summarized the advances in chemistry, biological effects, and toxicity research of S. grosvenorii during the past 30 years. Several different classes of compounds have been isolated or detected from various parts of S. grosvenorii, mainly triterpenoids, flavonoids, polysaccharides, amino acids, and essential oils. Various types of extracts or individual compounds derived from this species exhibited a wide array of biological effects e.g. anti-tussive, phlegm-relieving, anti-oxidant, immunomodulatory, liver-protecting, glucose-lowering, and anti-microbial. The existing research has shown that extracts and individual compounds from S. grosvenorii are basically non-toxic. Finally, some suggestions for further research on specific chemical and pharmacological properties of S. grosvenorii are proposed in this review.

Endovascular Microcatheter Provocation Test for the Diagnosis of Glossopharyngeal Neuralgia

Glossopharyngeal neuralgia (GN) is a rare disease often clinically misdiagnosed as trigeminal neuralgia. An endovascular provocative test has been applied to assist in making the diagnosis of GN caused by vascular compression. We similarly used endovascular provocative techniques to identify the causative vessel and to evaluate the indication for microvascular decompression (MVD) in two patients. Two patients had severe retroauricular and pharyngeal pain that could not be controlled by medical therapy. Magnetic resonance imaging and magnetic resonance angiography showed a high-riding right posterior inferior cerebellar artery (PICA). We decided to apply the endovascular provocation test to prove the assumed GN and identify potential indications for MVD. A loop of the PICA appeared to compress the glossopharyngeal nerve in the first patient. In this patient, a microcatheter was inserted into the right PICA, decreasing the GN. The patient underwent MVD, resulting in complete pain relief. In the second patient, a microcatheter was inserted into the right PICA, and an attack of typical GN occurred, with pain in the posterior region of the tongue, tonsils, oropharynx, and larynx. The patient's severe pain was clearly different from this typical GN caused by the microcatheter provocation test, and MVD was not performed. The diagnosis of GN is sometimes complex. The endovascular provocative technique may allow identification of GN caused by vascular compression.

症候性頚部頚動脈蛇行に対し手術的治療が奏功した1例

A 74-year-old woman presented with dysphagia, hoarseness, dry cough and deep pharyngeal pain that persisted and gradually progressed despite medication and nerve block anesthesia. A CT scan showed an unusually tortuous left cervical carotid artery that compressed and displaced the trachea and esophagus. Surgery was conducted to shorten the common carotid artery by resection of a 2-cm segment and to transpose the tortuous cervical internal carotid artery. Immediately following surgery, the patient’s pre-operative symptoms resolved. Tortuous cervical carotid artery is a rare cause of both specific and non-specific pharyngeal and laryngeal symptoms. Transposition and shortening of the tortuous artery is effective in reducing or eliminating the symptoms for cases in which the tortuous artery is identified as the cause of the symptoms.

Transoral, retromolar, para-tonsillar approach to the styloid process in 6 patients with Eagle’s syndrome

Objectives: Eagle’s syndrome is caused by an elongated or mineralised styloid process and characterised by facial and pharyngeal pain, odynophagia and dysphagia. Diagnosis is based on clinical findings. However radiologic imaging, like panoramic radiograph, helps to confirm the diagnosis. There are different treatments of the Eagle’s syndrome. Anti-inflammatory medication (carbamazepime, corticosteroids) and/or surgical interventions are established. The aim of the different surgical techniques is to resect the elongated styloid process near the skull base. Study Design: A transoral, retromolar, para-tonsillar approach was performed to expose and resect the elongated calcified styloid process in a consecutive series of six patients. The use of different angled ring curettes, generally used in hypophysis surgery, facilitated the preparation of the styloid process through the surrounding tissue to the skull base, without a compromise to the surrounding tissue. Clinical examinations were performed pre- and postoperatively (3 month and after 1 year after surgery) in all patients. Results: No intra- or postoperative complications were observed. The hypophysis ring curettes facilitated the preparation of the styloid process to the skull base. Conclusions: The transoral, retromolar, para-tonsillar approach is a secure and fast method to resect an elongated symptomatic styloid process. Side effects of the classical transoral trans-tonsillar approach did not occur. Key words:Retromolar, para-tonsillar approach, Eagle syndrome, clinical features.

Tonic stimulation of the pharyngeal mucosa causes pain and a reversible increase of inflammatory mediators

Objective and design To develop a model of the inflammatory component of non-infectious sore throat using tonic stimulation and quantification of inflammatory mediators in pharyngeal lavage fluid.Material or subjectsForty-five healthy volunteers.TreatmentCold dry air.MethodTonic stimulation of the pharynx was achieved using a constant stream of cold dry air to the back of the throat. Following optimization of stimulation conditions (phase 1), pharyngeal pain, irritation, and swallowing discomfort were assessed using visual analog scales, and the concentration of inflammatory markers were measured in pharyngeal lavage fluid (phase 2).ResultsOptimum conditions for tonic pharyngeal stimulation were cold dry air at 12 °C, relative humidity 20 %, at a flow rate of 12 L/min for 15 min. Analysis of pharyngeal lavage fluid collected 5 min after stimulation showed significant increases in prostaglandin E2 (P = 0.018), thromboxane B2 (P < 0.001), and substance P (P < 0.001), but no increase in peptidoleukotriene. When the stimulus was removed, the level of inflammatory markers in pharyngeal lavage fluid returned to baseline by 30 min post-stimulation. These objective measures mirrored subjective pain ratings.ConclusionsTonic stimulation of the pharyngeal mucosa with cold dry air causes pain and an increase of inflammatory mediators which are reversible.Electronic supplementary materialThe online version of this article (doi:10.1007/s00011-013-0663-7) contains supplementary material, which is available to authorized users.

Application des recommandations de la conférence de consensus devant des symptômes ORL, respiratoires ou des douleurs thoraciques considérés comme dus à un reflux gastro-œsophagien

The primary objectives of this observatory were: (1) to assess the prevalence of extradigestive symptoms (EDS) (asthma, pharyngeal pain, chronic hoarseness, nocturnal breathlessness, chronic or nocturnal cough, non-cardiac chest pain) which are suspected of being associated with gastro-oesophageal reflux (GERD) in a population consulting in general practice; (2) to compare the diagnostic and therapeutic approach adopted initially and at follow-up to the recommendations of the French-Belgian Consensus Conference on adult GERD (1999). The survey was conducted among 578 general practitioners (GPs). All EDS were investigated in patients (≥ 18 y.o.) consulting over 3 days. Only patients considered a priori as having GERD related EDS were included in study. At each visit (initial and at 1 and 4 months), the diagnostic and therapeutic approach was analyzed, scored, and the GP's certainty regarding the accountability of GER in the EDS rated using the visual analogue scale (VAS). The criteria used by GPs to evaluate GER accountability as certain or doubtful were examined. Out of 33,487 consulting patients, 14% presented EDS (cough: 6.7%; ENT symptoms: 7.7%; chest pain: 2.3%). Among patients presenting EDS, 22% (1063) were included in the study based on suspicion of GERD, whereas 45% (481) had neither history nor digestive symptoms typically associated with GERD. The diagnostic approach did not vary whether the patient presented typical EDS associated symptoms (A+) or not (A-): 83.7% of patients (A+) versus 86.5% (A-) immediately received acid reflux treatment; 4.6% (A+) versus 7.9% (A-) underwent additional testing and 5.2% (A+) versus 4.4% (A-) were referred to a specialist. In 87% of cases, acid reflux treatment included a proton pump inhibitor (PPI) (half-dose: 47.2%, standard dose 50.3%, double dose 2.5%); in 8.1% of patients initial acid reflux treatment included an H2 antagonist while in 3.2% of patients treatment included prokinetic drugs. At 4 months of follow-up, GERD accountability was considered certain in 74.7% of the patients included in the assessment (794/1063). The GPs opinion was based on response to acid reflux treatment in 92% of cases, on endoscopy in 6.7% of cases, on pH monitoring in 0.3% of cases and on a specialist's opinion in 6% of cases. There is a considerable difference between the recommendations of the French-Belgian Consensus Conference on adult GERD and the practices observed in general medicine. The diagnostic and therapeutic approaches were empirical with recourse to additional exams in less than 10% of cases. The degree of certainty as to GERD accountability was based primarily on response to PPI treatment.

Diagnosis and treatment of pyriform sinus perforation

To study the early diagnosis, treatment and Prognosis of pyriform sinus perforation. To study the clinical feature about 15 cases of pyriform sinus perforation, Most of the 15 cases with pyriform sinus perforation were associated with pharyngeal pain or fever. contrast x-ray studies and CT scan were used to confirm the perforation. conservative treatment in 9 cases and surgical intervention in 6 cases. and review relevant literature. Of all 15 cases, 9 cases with wild symptoms for conservative treatment, 6 cases with severe symptoms and complications were treated surgically. All achieved better clinical efficacy, By relevant examination, the perforation were healed within 2 - 4 weeks and none had re-perforation for 1 - 30 months follow-up. Pyriform sinus perforation with wild symptoms and within 12 hours can be treated conservatively. Large perforation (> 2 cm) last more than 12 hours or any complications require exploration, operation repair if possible and adequate drainage. early diagnosis and effective treatment can reduce the incidence of complications and improve the survival rate of patients.

Acute Myelogenous Leukemia with &lt;i&gt;Leptotrichia trevisanii&lt;/i&gt; Bacteremia

A 74-year-old woman visited an otolaryngology clinic with pharyngeal pain, and was diagnosed with a peritonsillar abscess. She received antibiotics and underwent incisional drainage, but displayed high white blood cell and blast cell counts, and was referred to our hospital. Gram-negative rods (Leptotrichia trevisanii) were detected in blood cultures performed on admission. She was diagnosed with bacteremia and acute myelogenous leukemia (FAB classification: M1). After antibiotic therapy, she temporarily recovered from the bacteremia, but subsequently died on day 34. Although Leptotrichia trevisanii bacteremia is extremely rare, clinicians should consider it in cases involving immunocompromised patients with oral lesions.

Hunt综合征误诊1例

本文介绍一例以咽痛为主诉的中年男性Hunt综合征患者，该病例不仅以咽痛主诉就诊，并可见扁桃体炎之体征，但治疗过程中发现，按扁桃体炎治疗无效果，并逐渐出现耳带状疱疹症状与体征。最后经治疗痊愈。 This paper introduces a case for complaint with pharyngeal pain middle-aged men Hunt syndrome patients. This case is not only to angina complained of a doctor, and visible tonsillitis, but the signs are found in the course of treatment, according to the tonsillitis treatment no effect, and gradually appear ear herpes zoster symptoms and signs. Finally, after treatment, the patients are healed.

Nasopharyngeal tuberculosis

Today, the opportunity to see tuberculosis is decreasing. Nasopharyngeal tuberculosis is a rare entity, even in endemic tuberculosis areas. A case of nasopharyngeal tuberculosis is described. A 28-year-old woman presented with a sore throat. Irregular mucosal thickening was seen in the nasopharynx. Staining for acid-fast bacilli was positive (Gaffky 1), and the PCR test was positive for Mycobacterium tuberculosis from pharyngeal mucus. Computed tomography showed mucosal thickening in the pharynx and old pulmonary tuberculosis in the right upper lobe. Multiple anti-tuberculosis drug therapy was performed for 6months. A few days after the initiation of therapy, the pharyngeal pain subsided. The irregular mucosal thickening was quite thin after 1month of multidrug therapy and was no longer observed after 2months. A case of nasopharyngeal tuberculosis is reported. A good result was obtained with multiple anti-tuberculous drug therapy for 6months. Nasopharyngeal tuberculosis should be considered in the differential diagnosis of a white nasopharyngeal coating, especially in a patient with a history of pulmonary tuberculosis.