To evaluate the impact of a clinical pharmacist managed medication refill clinic on physician workload. A retrospective case study was conducted for patients receiving refill authorizations or denials from the clinical pharmacist from 2008 to 2010. Data related to refill request volume and interventions undertaken were collected. A total of 5706 refill requests were processed by the clinical pharmacist during the study period. The collaboration decreased physician refill request volume up to 60%. Of the total amount of refill requests processed, 42% required the pharmacist to make an intervention. The most common interventions were reminders for follow-up. The collaboration between a clinical pharmacist and family physicians to develop a clinical pharmacist managed medication refill clinic decreased physician workload and improved patient care.