Dealing with the risk factors has got much attention specifically in the health and pharmaceutical industry. However, due to complex nature, several risk both financial and non-financial in nature are associated with the title of supply chain in pharmaceutical industry. The purpose of this research is to analyze the various risk factors which are linked with the supply chain in the pharma sector of Thailand to predict the trends in corporate repute. For this purpose, supply side risk factors, demand side risk factors, financial risk factors, and operational risk factors were selected from the existing literature of supply chain. Besides, reputational trends through five sub items were observed through set of these risk factors. To examine the relationship between the variables, a questionnaire was developed for the data collection in the economy of Thailand with a sample of 169 respondents. The results show that supply chain risk factors like lack of information sharing, lack of captain category supplier, interest rate risk, exchange rate risk, machine or equipment failure, quality risk are significantly and adversely impacting on the different dimensions of corporate repute in pharma sector of Thailand. Besides, detailed review of the literature has demonstrated that this research is among the initial contribution for discussing the relationship between supply chain risk factors and their influence on the corporate repute in pharmaceutical sector of Thailand. for this reason, various stakeholders would get the benefit from the study findings in compiling the future studies on the similar topic. However, research limitations like expanding the sample size, considering cross country analysis, and implication of structural modelling approaches may provide some interesting and different results in coming time.