Abstract Rock physics provides a dynamic tool for quantitative analysis by developing the basic relationship between fluid, lithological, and depositional environment of the reservoir. The elastic attributes such as impedance, density, velocity, V p/V s ratio, Mu-rho, and Lambda-rho are crucial parameters to characterize reservoir and non-reservoir facies. Rock physics modelling assists like a bridge to link the elastic properties to petrophysical properties such as porosity, facies distribution, fluid saturation, and clay/shale volume. A robust petro-elastic relationship obtained from rock physics models leads to more precise discrimination of pay and non-pay facies in the sand intervals of the study area. The Paleocene aged Lower Ranikot Formation and Pab sandstone of Cretaceous age are proven reservoirs of the Mehar gas field, Lower Indus Basin. These sands are widely distributed in the southwestern part of the basin and are enormously heterogeneous, which makes it difficult to distinguish facies and fluid content in the reservoir intervals. So, an attempt is made in this paper to separate the reservoir facies from non-reservoir facies by using an integrated approach of the petro-elastic domain in the targeted sand intervals. Furthermore, missing logs (S-sonic and P-sonic) were also synthesized in the wells and missing intervals along with improving the poor quality of the density log by captivating the washouts and other side effects. The calibrated rock physics model shows good consistency between measured and modelled logs. Petro-elastic models were predicted initially using petrophysical properties and incorporated at true reservoir conditions/parameters. Lithofacies were defined based on petrophysical cut-offs. Rock physics modelled elastic properties (Lambda-rho versus Mu-rho, impedance versus V p/V s ratio) were then cross-plotted by keeping lithofacies in the Z-axis. The cross-plots clearly separated and demarcated the litho-fluid classes (wet sand, gas sand, shale, and limestone) with specific orientation/patterns which were randomized in conventional petrophysical analysis.