Development Perspective Research Articles

The use of the Isolation Forest model for anomaly detection in measurement data

The subject of the research is the Isolation Forest model, which is a powerful and efficient tool for detecting anomalies in measurement data and outliers, applicable in various fields where ensuring high accuracy and reliability of measurements is important. The goal of the study is to apply the Isolation Forest model to identify unusual or anomalous patterns that differ from typical patterns in the output data. This is achieved by isolating anomalous patterns from normal ones through the construction of multiple different decision trees. The task of the research is to detect outliers in data obtained during the preparation for international comparisons on the state primary standard for mass and volume flow rate of fluid, mass and volume of fluid flowing through a pipeline, by measuring with a сoriolis flowmeter. Data collected during metrological studies undergo processing by the model to detect anomalies. This model analyzes the data and identifies anomalous or outlier values that may indicate systematic or random measurement errors. It enables quick and efficient detection of even the smallest deviations in the data, helping to maintain high accuracy and reliability of measurement results. The main methods for detecting outliers in statistical analysis, which are distribution-independent, are the Grubbs' criterion, interquartile range distribution, and standard deviation. They are sensitive to sample size but are simple and understandable tools. However, the Isolation Forest model also has its limitations, particularly it can be resource-demanding for large datasets. Additionally, it is necessary to consider that using the model requires proper parameter tuning to achieve optimal results. The results of the research include assessment of the Isolation Forest model's effectiveness by comparing it with traditional outlier detection methods. Comparative analysis of the results of different approaches to the same task is an effective method for evaluating the model's performance. Conclusion. The article concludes with the perspective of further research development in this direction. The work will focus on further developing methods for detecting anomalies in measurement data and improving the accuracy and reliability of measurement results in various application fields, which can find broad applications in science and industry.

New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives.

In recent years, synthetic lethality has been recognized as a solid paradigm for anticancer therapies. The discovery of a growing number of synthetic lethal targets has led to a significant expansion in the use of synthetic lethality, far beyond poly(ADP-ribose) polymerase inhibitors used to treat BRCA1/2-defective tumors. In particular, molecular targets within DNA damage response have provided a source of inhibitors that have rapidly reached clinical trials. This Perspective focuses on the most recent progress in synthetic lethal targets and their inhibitors, within and beyond the DNA damage response, describing their design and associated therapeutic strategies. We will conclude by discussing the current challenges and new opportunities for this promising field of research, to stimulate discussion in the medicinal chemistry community, allowing the investigation of synthetic lethality to reach its full potential.

Preventing Online Addictive Behaviors Promoting Active Online Use: Preliminary Findings in Italian Early Adolescents

<strong>Introduction:</strong> Information and Communication Technologies (i.e., ICT) are fundamental in everyone’s daily lives, especially for youths who integrate them into their routines as instruments for academic, relational, and entertainment purposes (Oka et al., 2021). Thus, it becomes crucial to differentiate positive or proactive online behaviors, which motivate people to interact directly with others and are positively associated with well-being, from negative or addictive online behaviors, which increase emotional, behavioral, or work-related and academic problems (Alimoradi et al., 2019; Gjoneska et al., 2022; Oka et al., 2021). Social and clinical policies are mostly focused on negative and addictive online behaviors in youths, due to their huge effects on mental health, which also significantly impact social and health costs to deal with these problems (Cañas & Estévez, 2021; Lopez-Fernandez & Kuss, 2020). To our knowledge, promotive policies and interventions in this field are still lacking, because they mostly focus only on the reduction of problematic behaviors rather than promoting individual or contextual protective factors (Cañas & Estévez, 2021; Li et al., 2020). Contrary to this trend, considering the potentiality of ICTs for youths, research is now highlighting the importance of considering both preventive and promotive components in online behaviors. According to the Positive Youth Development perspective (Lerner et al., 2018), which emphasized the importance of focusing on individuals’ resources and protective factors, a preventive-promotive intervention was developed and implemented in an Italian Junior High School, that aimed to contrast negative online behaviors, while promoting positive ones (La Rose et al., 2010). <strong>Aims of this Study:</strong> Thus, the present study preliminary investigated the effectiveness of this intervention, by analyzing longitudinal mean differences of two negative (i.e., problematic use of social network and smartphones) and two positive (i.e., searching for social support online, offering social support online) internet-related behaviors in youths. <strong>Method and Results:</strong> 358 youths (35% females; Mage=15.35, S.D.=.63) completed the Bergen Social Media Addiction Scale (Monacis et al., 2017), the Smartphone Addiction Scale (Kwon et al., 2013), and the Active and Passive Use of Social Networking Sites Scale (Remondi et al., 2023) in the pre-and-post intervention assessments. Repeated Analysis of Variances showed that smartphone and SNS addictions significantly decreased from pre-to-post assessments. In addition, offering and searching for social support on SN significantly increased across the two time points. <strong>Discussion:</strong> Our findings showed that addictive smartphone and SNS use significantly decreased in a short time period, while relational activities engaged with SNS significantly increased across the intervention. These results could suggest the short-term efficacy of the project and could be considered in the implementation of other school-based interventions, and in the implementation of more effective socioeconomic strategies to contrast internet-related addictive behaviors (Andreassen et al., 2017).

Entrepreneurship amid armed conflicts: Insights from Artsakh

Armed conflicts are exogenous shocks that engender multifaceted turbulence. This article explores the corporate behavior of companies operating in the active conflict of Artsakh and their strategic responses to the devastating war of 2020 by using multiple case studies. Building on the Business for Peace literature, this article contextualizes the mission and governance mechanisms of companies and their interlinkages with the company activities perceived as peace-enhancing. The research findings support existing evidence indicating that (semi)hybrid business forms are appropriate in unconventional contexts. The article unfolds the mechanisms that enable companies to work through conflict and identify key moderating factors that significantly affect their development perspectives. This study is the first to illuminate how companies from several sectors in a conflict-affected zone in the South Caucasus pursue different combinations of social and economic goals, maintain and develop relationships with stakeholders, and interact progressively with markets and institutions.

Pengembangan Flipbook “Dukung” tentang Peduli Lingkungan sebagai Media Dakwah pada Pembelajaran PAI Kelas 6 SD

This research aims to develop a flipbook entitled "SUPPORT" (Da'wah Cares for the Environment) as a medium for da'wah in 6th-grade elementary school Islamic Religious Education (PAI) learning that is effective for conveying environmental care da'wah messages, as well as testing the effectiveness of the flipbook in increasing understanding and a caring attitude towards the importance of caring for the environment in the context of Islamic religious teachings that are appropriate according to the assessment of material experts, media experts and students. The research method used in this development research is Design and Development (D&D), which has a focused objective on the process of designing and developing educational products, analyzing and evaluating these products from a design and development perspective. This research procedure uses the Analyze, Design, Develop, Implement, Evaluate (ADDIE) model, which is a learning development model that is effective, dynamic, and supports ongoing learning. The instruments for collecting this data are observation, material expert validation questionnaire, media expert validation questionnaire, student response questionnaire, and documentation. The results of the research show that the "SUPPORT" flipbook developed is very good and suitable for use in conveying environmental care da'wah messages. The conclusion of this research is that the development of flipbooks as a medium for preaching environmental care in PAI learning for grade 6 elementary schools can make a new contribution to delivering preaching material and environmental education in elementary schools.

Developmental Roots of Human Self-consciousness.

Human consciousness is considered in the perspective of early development. Infants and young children remind us that at its core, the problem of consciousness is primarily a problem of identity, in particular a problem of self-identity with others in mind. It is about how we feel and construe ourselves as an entity among other entities. It is about becoming co-conscious: Aware of oneself through the evaluative eyes of others. This development unfolds in the first 18 months of life, following major steps that are described, and arguably considered as a human trademark.

Next Generation Risk Assessment approaches for advanced nanomaterials: Current status and future perspectives

This manuscript discusses the challenges of applying New Approach Methodologies (NAMs) for safe by design and regulatory risk assessment of advanced nanomaterials (AdNMs). The authors propose a framework for Next Generation Risk Assessment of AdNMs involving NAMs that is aligned to the conventional risk assessment paradigm. This framework is exposure-driven, endpoint-specific, makes best use of pre-existing information, and can be implemented in tiers of increasing specificity and complexity of the adopted NAMs. The tiered structure of the approach, which effectively combines the use of existing data with targeted testing will allow safety to be assessed cost-effectively and as far as possible with even more limited use of vertebrates. The regulatory readiness of state-of-the-art emerging NAMs is assessed in terms of Transparency, Reliability, Accessibility, Applicability, Relevance and Completeness, and their appropriateness for AdNMs is discussed in relation to each step of the risk assessment paradigm along with providing perspectives for future developments in the respective scientific and regulatory areas.

Life Cycle Assessment of Large-Scale Solar Photovoltaic Plant based in Malaysia

Abstract A cradle-to-grave life cycle assessment (LCA) has been performed on a Large Scale Solar Photovoltaic (LSSPV) plant based in Peninsular Malaysia to study the detailed environmental impact of its life cycle. The LSSPV, with a capacity of 78 MWdc, is currently one of Malaysia’s largest solar power plants. The different life cycle phases of the LSSPV, starting from resource manufacturing and transportation, through plant construction and electricity generation, and to decommissioning of the plant, were assessed using the SimaPro software with the Ecoinvent v3.8 database. Results show that the overall emission rate for the LSSPV is 0.0309 kgCO2eq/kWh. It is estimated that the construction phase of the power plant, which includes activities such as infrastructure works and production of PV modules and Balance of System, yields the largest amount of kgCO2eq/kWh emission at 85.7% and imposes the highest environmental impact as compared to the other phases. The second biggest contributor is attributed to the transportation phase, contributing to 14.0% of the total kgCO2eq/kWh emission, of which most of the emission is emitted during the sea freight transportation of PV components from China port to Malaysia port (12.4%). A sensitivity analysis was performed to compare the environmental impact between open ground installation and the slanted roof installation mounting system of LSSPV. The findings from LCA proposed that open-ground installation has a greater negative impact on the environment because it involves additional land clearing and infrastructure transformation. The findings from this study serve as a benchmark for the LSSPV system in Malaysia and present technical perspectives for the future development of PV projects considering environmental impacts across the project lifetime.

An Empirical Analysis of the Content of Vocational Students Sports Activities Based on Video Data Segmentation and Mining From the Perspective of Motor Development

The key factor that promotes Vocational students development is the development of movement, which requires children to have excellent motor skills to develop their intellectual level, physical function and social adaptability in daily study and life. Data mining technology is an economical and practical core technology, which obtains useful information for the service system from a large amount of data. However, many teaching deficiencies in this area are prevalent in the field of early childhood education. In the current research on the content of Vocational students physical activities, a large amount of data information needs the support of data mining technology. This paper aims at how to combine data mining technology to study the content of Vocational students sports activities from the perspective of movement development, establish a decision support system for Vocational students sports activities, and conduct experiments on Vocational students sports activities from the perspective of action scientific arrangement and implementation of activity content, carry out empirical research on the content of Vocational students sports activities.

FINANCIAL INCLUSION: DOES IT PLAY AN IMPORTANT ROLE IN A COUNTRY? REVIEW OF THE LITERATURE

Financial Inclusion (FI) is a key pillar of financial development and inclusive growth in a country. It plays an immense role and is showing an evolving nature around the world. Most research now investigates this concept mainly due to its supportive nature for a country’s development perspectives. Many countries make investments and pay considerable attention to initiating FI agendas and national FI strategies to improve the level of FI in their countries. Economic empowerment through formal financial sector activities, poverty reduction, lowering income inequality, enhancing savings and investments, and improving productivity are some of the contributory factors of FI. Reviewing nearly 50 past literature, this article attempts to develop new literature regarding the importance of FI for a country. Furthermore, the study examines FI definitions and barriers to FI. The findings of the literature reveal that FI directly supports the achievement of a country's growth objectives. The main contributory factors of FI are employment creation, reducing income inequality and poverty, smoothing the financial sector while maintaining financial system stability, and working with technological developments towards financial activities. However, there are several important bottlenecks such as lack of income, difficult access points due to long distance, barriers to digital finance and payments, and lack of financial knowledge. Affordable financial sector products and services for everyone tend to improve the level of FI. The outcome of the research provides valuable insight for policymakers and responsible authorities to take proactive actions to reach the FI targets by eliminating barriers to FI. In this regard, higher participation of the population towards the formal financial sector in a country is an important element, and actions should be arranged for the gradual transformation of people to achieve this target. The findings of this study further provide avenues for future studies and policy-level decisions, highlighting the fact that FI is an important concept for creating a financially inclusive country.

Perspectives of Farm Development Under the War Conditions in Ukraine

Perspectives of Farm Development Under the War Conditions in Ukraine

Prototype of a web tool for psycho-pedagogical intervention and stimulation of children with ADHD

Digital tools for students with ADHD have been scarcely implemented in current education due to the challenges they pose. Therefore, rigorous research, from the perspective of web application development, will strengthen students' formative process. In the present study, a web platform prototype was developed to automate the process of psycho-pedagogical intervention in children aged 5 and 12 with ADHD, focused on evaluating how this tool contributes to the process of psycho-pedagogical stimulation. The prototype was developed using XP methodology divided into two general phases and semi-structured interview techniques and structured surveys to gather relevant information. The first general phase involved the construction of the prototype, which included applying the interviews to obtain the system requirements and the BPMN process model of the general pedagogical approach. Interface design, architecture design, and prototype development were also carried out. The second general phase evaluated the system through acceptance and load and stress tests. Finally, usability evaluation was conducted following ISO 25010 and ISO 25040 standards. The usability measure obtained was "good," defined according to decision criteria, allowing us to infer the impact of implementing web tools.

The 5Cs of positive youth development: their impact on symptoms of depression, anxiety, stress, and emotional distress in Chilean adolescents

Effective approaches to addressing mental health challenges faced by adolescents require a deep understanding of the factors contributing to optimal development, well-being, and prosperity. From the perspective of Positive Youth Development (PYD), this study proposes to examine the relationship between the 5Cs of PYD (Competence, Confidence, Connection, Character, and Caring) and symptoms of depression, anxiety, stress, and emotional distress among Chilean adolescents. A quantitative, cross-sectional, non-experimental study was conducted with 425 adolescents (ages 12 to 19, M = 14.95, SD = 1.81) from three Chilean cities: Arica (23%), Alto Hospicio (32%), and Iquique (46%). Data analysis included the use of confirmatory factor analysis (CFA) and structural equation modeling (SEM). The results indicate that two of the 5Cs, Confidence and Connection, have a significant negative direct effect on the four evaluated criterion indicators. These findings contribute to the literature on positive youth development in Latin America and underscore the importance of fostering confidence and connection in interventions aimed at promoting the mental health of adolescents in Chile and in similar contexts.

Regenerating small historic villages. Possible strategies through the vision of experts

ABSTRACT This article aims to explore the critical issues and strategies for the enhancement and regeneration of small Italian historic villages, making use of the opinions of experts from different backgrounds, collected in the context of open-ended interviews. The analysis of the results of the interviews paints a nuanced picture of the challenges facing these communities, which include environmental and economic sustainability, demographics, access to essential services, and the preservation of cultural identity. The integration of perspectives derived from interviews with politicians, technicians, health professionals and cultural experts highlights the importance of a multidisciplinary approach to address the complexity of the challenges. Themes emerge such as the need for strategies that can be adapted to local specificities, the active involvement of local communities in decision-making and a delicate balance between preservation of traditions and innovation. The article’s conclusions underline the urgency of flexible strategies that can adapt to the changing needs of these communities. As a whole, the work offers a contribution to the debate on regeneration policies, offering key ideas to orient the future of the many smaller Italian historic centers towards a perspective of sustainable and lasting development.

Towards a debinding-free additive manufacturing of ceramics: A development perspective of water-based LSD and LIS technologies

Ceramic additive manufacturing (AM) requires a complex process chain with various post-processing steps that require expensive machines and special expertise. The key to further market penetration is AM that makes it possible to integrate into an already established ceramic process chain. Most successful AM technologies for ceramics are, however, based on processes that initially have been developed for polymeric materials. For ceramics AM, polymers or precursors are loaded with ceramic particles. This strategy facilitates the entry into AM, however the introduction of organic additives into the ceramic process chain represents a considerable technological challenge to ultimately obtain a ceramic component after additive shaping. In the present communication, two technologies based on ceramic suspensions will be introduced, the “layerwise slurry deposition” (LSD) and “laser induced slip casting” (LIS) technology. Both technologies take advantage of the high packing densities reached by conventional slip casting and moreover enable the processing of fines, even nanoparticles.

Research on Public Policies to Promote the Organic Connection Between Rural Revitalization and Poverty Alleviation

Poverty alleviation is foundational to maintaining Chinas comprehensive progress towards a moderately prosperous society. Rural revitalization is a crucial measure to further realize the modernization of agriculture and rural areas. The organic connection between these two is a focal issue in the development process of China's agricultural and rural areas, playing a strategic support role in achieving Chinas second centennial goal. Based on this, this paper focuses on the organic connection between poverty alleviation and rural revitalization in the new era. By summarizing the basic background and overall connotations of both, and employing a research methodology that integrates theory with practice, this study explores the achievements and inherent logical relations of poverty alleviation and rural revitalization at this stage, as well as the strategic significance of their integration in various aspects. With the shift of strategic focus to the "three rural issues," promoting the organic connection between poverty alleviation and rural revitalization may face challenges from group coverage, spatial scope, work objectives, task deadlines, and policy allocation in the future. Therefore, this paper further proposes feasible suggestions for the implementation of governance policies that promote the organic connection between poverty alleviation and rural revitalization from the perspectives of people, society, organizations, institutions, and development.

Balancing Protection of Plant Varieties and Other Public Interests

The interplay between intellectual property rights for new plant varieties and public interests, particularly farmers’ rights, is critically examined within the context of global agricultural practices and Sustainable Development Goals (SDGs). According to the Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS), World Trade Organization (WTO) members shall establish a mechanism to grant effective protection to new plant varieties. There are two typical compliance mechanisms with TRIPS: the model developed by the International Convention for the Protection of New Varieties of Plants (UPOV Convention) and India’s sui generis system. A comparison from the sustainable development perspective is conducted through the textual analysis of the regulations of each model. The results show that the UPOV Convention cannot advance the achievement of Sustainable Development Goals and might have adverse effects. Conversely, India’s sui generis system represents a more balanced approach, addressing the needs of the farmers, the community, and environmental protection alongside those of breeders and benefitting sustainable development. The conclusion advocates for revising the UPOV Convention to incorporate broader concerns, including farmers’ rights and environmental sustainability, to ensure a more equitable approach to the protection of plant varieties.

Transferability of new methods for health technology assessment in the field of diabetes between early and late adopters’ countries

This study aimed to investigate the transferability of novel artificial intelligence (AI) methods for prediction modelling of diabetes based on real-world data (RWD) between early and late adopters of emerging health technologies from the perspective of developers and health technology assessment (HTA) experts. A two-step approach was used. Developers of the new AI methods within HTx consortium completed a survey about the benefits, usability, barriers associated with implementing the new prediction models in routine HTA practices. Then, HTA experts from Central and Eastern European (CEE) countries participated in a focus group discussion. Developers generally expressed optimism regarding the transferability of the methods, while acknowledging potential disparities across CEE countries. Key benefits that were identified included enhanced understanding of diabetes, improved cost-effectiveness modelling, and refined patient stratification, all of which could contribute to clinical and reimbursement decisions across various jurisdictions. The focus group underscored the value of real-world data for diabetes prediction modelling, serving as a beneficial resource for both clinicians and HTA agencies. However, there was a recognized need to clarify the processes of integrating randomized clinical trial data with real-world data. For the other stakeholders, the advancement of the methodology will improve the diagnosis and therapy during the process of decision making. Experts from CEE countries recognized the potential of artificial intelligence-based methods employing real-world data for diabetes modelling. These methods are seen as instrumental in elucidating the heterogeneous nature of the disease, supporting clinician decision-making and holding promises for HTA purposes.

The governance of peri-urban green infrastructures in the perspective of sustainable development. A Comparison in Europe

The paper analyses the governance models of six peri-urban green infrastructures (GIs) in Europe to reflect on GIs as critical loci to operationalize the sometimes naïve and rhetorical aim of sustainable development. In the study, the case of “Corona Verde”, the green belt around the City of Turin (Italy), is compared with other peri-urban GIs to discuss the potential of territorial governance for the construction of objective-led deliberative arenas as promoted by the UN 2030 Agenda for Sustainable Development. As a result, the hypothesis that peri-urban GIs are the most appropriate territorial systems to organise and manage a viable system of sustainability objectives is discussed and reframed. Although limited in scope and data, original traits of this study are the development of a territorial benchmarking comparing governance models rather than territories and the operationalisation of the governance for sustainability in terms of a continuous negotiation between the socio-ecological actors of a given territorial system.

A methodological study on the identification of ecological security change processes and zoning control strategies —— Based on the perspective of sustainable development

Ecological security (ES) is a crucial indicator for assessing the sustainable development of a region. Currently, most studies on ES primarily focus on process analysis, and the integration of environmental variability into the development of tailored control strategies for regions with varying ecological quality is overlooked. Therefore, in this study, we identified regional ES change processes, employed an optimized system to calculate the ecological security index (ESI), and identified ecological corridors (ECs) through the Minimum Constrained Resource (MCR) model to determine zoning strategies for typical arid regions, using the Ningxia region in the Yellow River Basin of China as an example. The findings showed that (1) from 2006 to 2020, the ESI values of most regions were between 0.2 and 0.4, with small but consistent increases in the ESI values over the years. (2) The proportion of regions with high ES ratings increased by 9.08 % across all districts and counties, and the center of gravity of ES shifted in a north–south and east–west direction. (3) The ESI exhibited a strong positive spatial correlation, characterized by spatial diffusion and spillover effects in most regions. (4) The ECs were predominantly distributed in a north–south direction, involving a total of 20 districts and counties. Based on the principles of sustainable development, we developed a model for the dynamic identification and zoning control of regional ES, aiming to provide a practical framework for effective ecological restoration and protection measures. Additionally, the strategies and methodologies presented in this study serve as important references for similar regions worldwide to facilitate the zoning control of ES, highlighting the broader significance and applicability of the study.