The article deals with the presence of religion in the life and work of Ukrainian public and cultural figure, doctor, writer and thinker Yuri Lypa. The definition of „religiousness” is given, relevant biographical facts found, non-random works are analyzed. Yuriy Lypa is a native of Poltava region (town of Stari Sanzhary, April 22, 1900, 5.05 in the new style). After the adoption by his family of his father – a doctor, writer, politician Ivan Lypa – he lived in the Odessa region (1909-1918). Participant in revolutionary events in Odessa (1917–1918), co-founder of the publishing house „Narodni Styag” (1917–1936). Yu. Lypa studied law at Odessa (1918) and Kamyanets-Podilsky (1919–1920) universities and medicine at the universities of Poznan (1922–1928) and Vilno (1932). During 1929–1943 Yu. Lypa lived in Warsaw, where he carried out his medical, literary, scientific and public activities. Member and co-organizer of the literary groups „Soncecvit” (1921) and „Tank” (1929), the Ukrainian student corporation „Chornomore” (1925–1933), the Ukrainian Economic Bureau (1933–1934); Ukrainian Black Sea Institute (1940–1944). Yu. Lypa’s creative legacy includes more than 360 poetic and prose works, publicistic and medical works. The last year of his life (1943–1944) was in the Lviv region (Yavoriv, Buniv and Ivanyky). Yu. Lypa was tortured by the enkavedysts on August 19, 1944 for being a UPA doctor. From many interpretations of religiosity as spirituality and faith, religious knowledge and practices, the subjective manifestation of the existence of religion, etc., to analyze the emergence of this worldview trait chosen understanding of the phenomenon by the Pope Ivan Pavlo II: „Religiousness originates from a deep human desire for truth and underlies the free and personal search for the divine”. Yuri Lypa’s religiousness arose and deepened under the external influence (origination, upbringing, environment) and the internal needs of personal development, as well as a result of his spiritual experience, including spiritual practices.