One way or another, students face certain difficulties and disadvantages of distance learning. This can affect students physically and emotionally if appropriate measures are not taken. The solution might be the personalization of distance learning process, which implies the application of individual approaches to learning. The article aims to determine the academic performance of students who use the system of personalized distance learning Quiz Guide. For this study, 140 students were selected. The results of the performance analysis showed that the experimental group scored higher on the final test, indicating that students using the Quiz Guide learning system had significantly better academic achievement than those who took the traditional approach to learning. According to the post-test results, the control group scored (average) 65.14 points, the experimental group, 74.71. Keywords: Academic performance, computer learning system, individualized approach, personalized distance learning, Quiz Guide system.