The aim of this study was to examine the relationships between personality factors and the symptomatology of fatigue among people with chronic fatigue syndrome (CFS), and compare them to people from the general population. Seventy-seven CFS patients (47 women, 30 men) were compared with 72 healthy individuals (44 women, 28 men) to investigate whether personality factors are related to the symptomatology of fatigue. All participants were asked to complete the NEO Five Factor Inventory (NEO-FFI), the Modified Fatigue Impact Scale (MFIS), the Fatigue Severity Scale (FSC), and the Mental Health Inventory (MHI). The results revealed that the CFS group reported higher levels of neuroticism and conscientiousness than the control group. These two personality factors were significantly related to fatigue symptoms, impact, and severity in both groups. These findings suggest that personality factors of neuroticism and conscientiousness may play an important role in the development and perpetuation of fatigue symptoms.
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