Background and ObjectivesThis study investigates the association of sociodemographic and attitudinal factors with blood donation frequency in Turkey that may contribute future strategies on donor recruitment.Materials and MethodsA face‐to‐face interview was designed including items about history of prior donations and about attitudinal factors such as personal beliefs, moral norms and personal satisfaction with donation experiences among first‐time, returning and regular donors. Binary logistic regression analysis was used to estimate the effect of donor characteristics, sociodemographic and attitudinal variables.ResultsTotally, 7400 whole blood donors attended to the study (20% first‐time, 39% returning and 41% regular donors). Most donors were men; however, women clearly more often donate for the first time and donate less regularly. Age showed a clear effect on the chance of being both of returning and regular donors. Employed returning donors were less likely to return to donation. Education status affected first‐time donation negatively whereas affected regular donation positively. Level of income affected first‐time donation negatively whereas affected returning to donation positively. Blood need of a family member affected on returning to donation and regular donation; however, the conditions of donation units such as ventilation or crowdedness affected on lapsing.ConclusionOur results show that age, gender, socio‐economic‐status and attitudinal factors were associated with being a first‐time, returning or regular donor. These data provide Turkish Red Crescent with knowledge on Turkish donor population, which help to build donor recruitment and retention policies.