Persistent Trait Research Articles

In situ predator exposure creates some persistent anti-predator behaviours: insights from a common environment experiment

Prey naiveté has been implicated in the global decline and reintroduction failure of many threatened species. A number of tools have been developed to combat prey naiveté including in situ predator exposure using live predators. However, determining the effectiveness and persistence of these interventions can be difficult, and requires comparisons of individual responses from predator-naïve and predator-trained populations. Even when this occurs, interpreting behavioural responses can be challenging because of the constraints of experimental design in large scale population manipulations. We used a common environment experiment and placed burrowing bettongs (Bettongia lesueur) from predator-free and predator-exposed populations together in an 8 ha fenced paddock. The predator-exposed population had been previously exposed to feral cats (Felis catus) under controlled wild conditions for up to six years and initial work suggested this exposure had led to physical and behavioural changes. Within our common environment experiment we compared a range of anti-predator behaviours including trap and feeding behaviour and response to predator scent and models. We found evidence for persistent trait changes up to 7 months, the latest time behaviours were tested, after bettongs were moved to the predator-free common environment and isolated from predators. These behaviours include reduced alarm rates, preference for open areas, and responses to predator scent and model stimuli. Additionally, high risk predator cues were more likely to elicit anti-predator responses than passive measures of anti-predator behaviour. Our design shows that predator exposure leads to persistent shifts in some, but not all, anti-predator behaviours. Identifying the proximate basis of anti-predator traits is important to develop successful tools to combat prey naiveté.

Species preference for seagrass restoration using vertical distribution model in Tidung Island, Indonesia

Tidung Island is one of the small inhabited islands and a tourist destination that allows the degradation of seagrass meadow and requires physical restoration using transplantation techniques. The seagrass species’ preference suitability needs to assess with this island for this case. This study aims to provide information on species that are possible to choose in seagrass transplantation based on their growth zones. The number of seagrass species, depths, and types of substrates was taken using seagrasswatch guideline by line transects along the coast to the reef slope with 10% plot intervals from the total length of the transect. Seagrass growth is divided into three zones: near the coast (back), middle, and near the reef slope (front). Enhalus acoroides, Cymodocea rotundata, and Thalassia hemprichii were found in almost all zones. Halophila ovalis, Halophila minor, and Halodule uninervis were distributed in the middle to front zone, while Syringodium isoetifolium was only in the middle zone. These findings suggest that transplant areas with high anthropogenic disturbances can use Enhalus acoroides and Thalassia hemprichii because they have the persistent trait. Meanwhile, the areas with low anthropogenic disturbance and low nutrients can use Halophila spp. and Halodule spp., because they can grow shoots and recover quickly.

Measuring attentional bias in smokers during and after psychosocial stress induction with a Trier Social Stress Test in virtual reality via eye tracking.

Attentional bias (AB) is considered an important factor not only in the etiology of addiction, but also with respect to relapse. However, evidence for the predictive ability of AB for relapse is not robust. One reason for this might be fluctuations of AB due to stress. Therefore, the current study investigated whether AB was present during and after stress induction and whether AB was enhanced by stress induction. A Virtual Reality (VR) adaptation of the Trier Social Stress Test (VR-TSST) was used to induce psychosocial stress in smokers (n = 34) and non-smokers (n = 37) followed by a novel free-viewing task in VR. Eye tracking data was recorded to examine gaze behavior to smoking-related and neutral stimuli presented in the VR-TSST and the free-viewing task. Stress ratings increased significantly from baseline to post VR-TSST in smokers and non-smokers. During the VR-TSST we observed, more frequent, longer, and earlier fixations on smoke-related compared with neutral stimuli without significant group differences. However, in the free-viewing task following the stress induction, a specific AB of smokers in terms of earlier and longer fixations on smoke stimuli was found. Results indicate that AB is not a persistent trait in smokers, but is context dependent. It is suggested that emotional learning processes such as smoking in the context of relief after stress may contribute to changes of AB both in terms of increased initial attention and deeper stimulus processing. Additionally, the potential of the VR-TSST to induce psychosocial stress could be replicated.

‘Tis Pity She’s (Still) a Whore: Mary Magdalene in The Chosen

Abstract Early Jesus films reveled in the traditional, historically inaccurate interpretation of Mary Magdalene as a penitent prostitute. While films produced since the 1980s are less heavy-handed in explicitly sexualizing or shaming Mary, promiscuity remains her most persistent trait. Traces of the penitent prostitute are detectable in The Chosen, a crowd-funded evangelical series on the life of Jesus which foregrounds Mary as a disciple. Her story arc in The Chosen mirrors that of the prostitute protagonist in Redeeming Love (2022), another evangelical film based on Francine River’s fictional adaptation of the Hosea/Gomer story. Both works adhere closely to what film scholar, Russell Campbell, identifies as the ‘martyr’ character type and ‘love story’ narrative structure commonly found in cinematic depictions of sex work. Ultimately, these films reinscribe patriarchal ideology when the woman is rescued and reformed by a virtuous man at risk of his own reputation.

Long‐term minnow community trait shifts and metacommunity dynamics in a geomorphically unstable river

AbstractEcological disturbances may affect both habitat connectivity and heterogeneity, changing the dominant metacommunity processes affecting local communities. Altered fluvial sediment dynamics in rivers experiencing headcutting and accelerated erosion may foster morphologically unstable reaches in which supplies of habitat‐forming materials are spatially and temporally unpredictable. We hypothesise such environments will select for species with traits which promote dispersal or rapid resource use. We tested this hypothesis using historical and recent datasets from a biologically and functionally diverse taxonomical group, minnows (Leuciscidae and Cyprinidae) in the Bayou Pierre, Mississippi. Local communities decreased in both α and β‐diversity over time. Spatial autocorrelation of communities was consistently high through time, and more strongly related to regional community structure than local habitat variables in contemporary data. Communities shifted towards species with larger body sizes, less parental care, shorter age at maturity and higher fecundity. Communities also shifted towards more generalist species with lower potential trophic positions, and keystone species declined. Our data support the hypothesis of community‐level shifts towards species with dispersal trait syndromes and opportunistic resource utilisation. These shifts have led to a decrease in ecological complexity and overall homogenisation of minnow communities in the geomorphically evolving Bayou Pierre mainstem. The Bayou Pierre presents a unique window into ecological dynamics in a watershed characterised by altered sediment dynamics and sediment loss, in contrast to the large body of literature examining systems with increased sedimentation. These insights demonstrate the importance of studying the full range of fluvial sediment dynamics, including how broader processes of loss and transport may affect long‐term habitat stability, persistent trait syndromes and metacommunity dynamics.

Objective rapid eye movement sleep characteristics of recurrent isolated sleep paralysis: a case-control study.

Recurrent isolated sleep paralysis (RISP) is a rapid eye movement (REM) parasomnia characterized by a dissociative state with characteristics of REM sleep and wakefulness. Pathophysiology has not yet been clarified and very little research has been performed using objective polysomnographic measures with inconsistent results. The main aim of our study was to find whether higher REM sleep fragmentation is consistent with the theory of state dissociation or whether signs of dissociation can be detected by spectral analysis. A total of 19 participants in the RISP group and 19 age- and gender-matched participants in the control group underwent two consecutive full-night video-polysomnography recordings with 19-channel electroencephalography. Apart from sleep macrostructure, other REM sleep characteristics such as REM sleep arousal index, percentage of wakefulness and stage shifts within REM sleep period were analyzed, as well as power spectral analysis during REM sleep. No difference was found in the macrostructural parameters of REM sleep (percentage of REM sleep and REM latency). Similarly, no significant difference was detected in REM sleep fragmentation (assessed by REM sleep arousal index, percentage of wakefulness and stage shifts within REM sleep). Power spectral analysis showed higher bifrontal beta activity in the RISP group during REM sleep. The results showed an underlying persistent trait of higher cortical activity that may predispose patients with sleep paralysis to be more likely to experience recurrent episodes, without any apparent macrostructural features including higher REM sleep fragmentation.

Conspiracy, Complicity, Critique

Conspiracy, Complicity, Critique Peter Knight (bio) The coronavirus pandemic and the storming of the Capitol have created a perfect storm of conspiracism, especially visible on social media. Many commentators have returned to Richard Hofstadter's analysis of the "paranoid style in American politics" to make sense of the surge of conspiracy-minded populism and the spread of disinformation. Conspiracism is usually framed as beyond the pale of rational discourse, a symptom and a cause of the delegitimization not only of the media, scientific expertise, and democratic institutions, but also of the very idea of objective truth (see Rosenblum and Muirhead 2019 on the nihilistic tendencies of the "new conspiracism" of post-truth politics). But does Hofstadter's diagnosis of the paranoid style still make sense today, when, for example, President Trump himself was one of the most significant "superspreaders" of misinformation about the coronavirus and the 2020 election (Evanega et al. 2020)? Although Hofstadter acknowledges that the paranoid style is a persistent trait in American politics, he nevertheless insists that it is "the preferred style only of minority movements" (1996, 7). Hofstadter, like other consensus historians and sociologists in the 1950s and 1960s, wanted to explain but also to stigmatize what they regarded as mass political delusions (see Butter 2014; Thalmann 2019). In effect, they wanted to diagnose but also quarantine conspiracism as a dangerous tendency, to put clear water between conspiracy thinking and more respectable ways of making sense of historical causality. Either you believe that nothing happens by accident, that nothing is as it seems, and that everything is connected (Barkun 2013), or you think that way of understanding historical causation and collective agency is a delusional fantasy. In contrast, this essay will explore the territory between conspiracy and not-conspiracy, focusing on notions such as collusion, complicity, and critique, which are neither the same as conspiracy, nor simply its opposites. The question is whether it is possible, under conditions of neoliberalism that make it harder than ever to trace lines of corporate and governmental accountability, to talk about problems of collective action and occluded power without lapsing into a conspiracy theory. Only by recognizing the affinities and disavowals between the rational mainstream and its marginalized, irrational counterparts can we begin to understand the seductive appeal and expressive functions of conspiracy theory as an act of communal political [End Page 197] identification, rather than merely a "crippled epistemology" (Sunstein and Vermeule 2009, 211) whose mistaken propositions can be combatted through fact-checking corrections. To do so, I'll first sketch out cock-up, complexity, and contingency theories, before going on to consider how conspiracy theories constitute both a distorted critique of neoliberalism, while at the same time also distracting and diverting their believers from more concerted forms of political opposition. The Conspiracy Theory of Society What is the opposite of a conspiracy theory? One common answer is what might be termed contingency theory, the assumption that there is no underlying plan or meaning to history. Another—closely aligned—possibility is the cock-up theory (as it is termed in the British colloquialism; see McKenzie-McHarg and Fredheim 2017), the notion that things rarely go to plan, often as a result of incompetence rather than intention. A third, related option is complexity theory, the idea that order emerges spontaneously out of a complex system without there being anyone behind the scenes secretly in command. All three answers assume that there is a clear divide between conspiracy theory and its opposites, with conspiracy theory viewed as an unsophisticated, inaccurate, and harmful mode of thought. Although the expression "conspiracy theory" had been used from time to time in the late nineteenth century, Karl Popper provided the first explicit definition of the phenomenon and its opposites (Thalmann 2019; McKenzie-McHarg 2020). He began to formulate what he called "the conspiracy theory of society" (2002, 94; his italics) in two lectures delivered in the late 1940s, before working this argument into the American edition of the second volume of The Open Society and Its Enemies in 1950. It is "the view that an explanation of a social phenomenon consists in the discovery of the men or groups who are interested in the occurrence...

Sociability trait and regional cerebral oxidative metabolism in rats: Predominantly nonlinear relations

Deficits in social behaviour are common in psychopathological conditions e.g., depression, autism and schizophrenia. In rats, sociability, defined as the engagement of an animal in non-aggressive social contact with a conspecific in a neutral arena, is as a persistent trait. To elucidate the neuroanatomy of social behaviour in animal models, long term neuronal energy metabolism was studied in rats preselected for sociability levels. Rats were divided into groups with high, medium and low sociability levels (HS, MS and LS) according to the average score of three social interaction tests, and cerebral long-term energy metabolism was assayed with cytochrome oxidase histochemistry. In the dorsomedial caudate putamen oxidative metabolism was linearly dependent on sociability, with LS-rats having the highest levels. In median preoptic nucleus, posterior paraventricular thalamus and median raphe, nonlinear relations appeared, HS- and LS-rats having lower oxidative activity than MS-animals. In the supraoptic nucleus MS-rats displayed lower oxidative activity than HS- and LS-animals. Intra-individual variability in social interaction on different testing occasions correlated positively with oxidative metabolism in the prelimbic cortex, bed nucleus of stria terminalis and caudate putamen, and negatively in the nucleus accumbens core. Conclusively, rats with different sociability levels are distinguished by long-term energy metabolism in nuclei involved in motivational behaviour, fear and vigilance; the relationship between energy metabolism and sociability appears to be predominantly nonlinear − animals with high and low expression of sociability are similarly deviant from the average; and intra-individual variability in social interaction is related to brain areas controlling motivation, stress reactivity and anxiety.

Recollection Bias and Its Underpinnings: Lessons from Terrorism Risk Assessments.

Recollection bias is the phenomenon whereby people who observe a highly unexpected event hold current risk beliefs about a similar event that are no higher than their recollection of their prior beliefs. This article replicates and extends the authors' previous study of recollection bias in relation to individuals' perceptions of the risks of terrorism attacks. Over 60% of respondents in a national U.S. sample of over 900 adults believe that the current risk of a future terrorist attack by either an airplane or in a public setting is no higher than they recall having believed, respectively, before the 9/11 attack and before the Boston Marathon bombing. By contrast, a rational Bayesian model would update to a higher currently assessed risk of these previously uncontemplated events. Recollection bias is a persistent trait: individuals who exhibited this bias for the 9/11 attack exhibited it for the Boston Marathon bombing. Only one-fifth of respondents are free of any type of recollection bias. Recollection bias is negatively correlated with absolute levels of risk belief. Recollection bias in relation to highly unexpected terrorist events-the belief that perceived risks did not increase after the surprise occurrence-dampens support for a variety of anti-terrorism measures, controlling for the level of risk beliefs and demographic factors. Persistent recollection bias for both 9/11 and the Boston Marathon bombing is especially influential in diminishing support for protective policy measures, such as surveillance cameras in public places. Given that public attitudes influence policy, educating the public about risk is critical.

Ancestor Worship and the Longevity of Chinese Civilization (祖先崇拜与中华文明的长期延续)

Although an impressive body of literature is devoted to the practice of venerating ancestors in China and other places, there is little agreement on what ancestor worship is, where it is practiced, and whether it is an ancient and persistent trait. Ancestor worship, we argue, is an ancient trait that has persisted in China, as in other parts of the world, since prehistoric times. We also discuss its universal aspects, including those associated with teaching it and with encouraging its persistence across generations. We end by discussing the function of ancestor worship in China. Has it been an impediment to progress, as Christian missionaries and communists insisted, or, as Ping-Ti Ho claimed, has it promoted the “longevity of Chinese civilization”? We argue that both claims may be correct, depending on the definition of progress and the characteristics associated with China’s two forms of ancestor worship. 虽然已有大量文献讨论中国和世界其他地区的祖先敬拜，但学界没有对祖先崇拜的性质、地域、历史性和持续性达成一致的认识。本文认为，中国的祖先崇拜，与世界其他地区类似，是一个源自史前时期，持续至今的现象。本文还分析祖先崇拜的普遍性特征，正是这些特征使得其代代相传。本文最后将讨论祖先崇拜的功能。它是像基督教传教士所言阻碍了中国的进步，还是如何炳棣所宣称，促进了“中华文明的长期延续”?我们认为这两种观点正确与否取决于进步的定义以及中国祖先敬拜的具体形式。 (This article is in English.)

Accumulation of inorganic polyphosphate enables stress endurance and catalytic vigour in Pseudomonas putida KT2440

BackgroundAccumulation of inorganic polyphosphate (polyP), a persistent trait throughout the whole Tree of Life, is claimed to play a fundamental role in enduring environmental insults in a large variety of microorganisms. The share of polyP in the tolerance of the soil bacterium Pseudomonas putida KT2440 to a suite of physicochemical stresses has been studied on the background of its capacity as a host of oxidative biotransformations.ResultsCells lacking polyphosphate kinase (Ppk), which expectedly presented a low intracellular polyP level, were more sensitive to a number of harsh external conditions such as ultraviolet irradiation, addition of β-lactam antibiotics and heavy metals (Cd2+ and Cu2+). Other phenotypes related to a high-energy phosphate load (e.g., swimming) were substantially weakened as well. Furthermore, the ppk mutant was consistently less tolerant to solvents and its survival in stationary phase was significantly affected. In contrast, the major metabolic routes were not significantly influenced by the loss of Ppk as diagnosed from respiration patterns of the mutant in phenotypic microarrays. However, the catalytic vigour of the mutant decreased to about 50% of that in the wild-type strain as estimated from the specific growth rate of cells carrying the catabolic TOL plasmid pWW0 for m-xylene biodegradation. The catalytic phenotype of the mutant was restored by over-expressing ppk in trans. Some of these deficits could be explained by the effect of the ppk mutation on the expression profile of the rpoS gene, the stationary phase sigma factor, which was revealed by the analysis of a PrpoS → rpoS‘-’lacZ translational fusion. Still, every stress-related effect of lacking Ppk in P. putida was relatively moderate as compared to some of the conspicuous phenotypes reported for other bacteria.ConclusionsWhile polyP can be involved in a myriad of cellular functions, the polymer seems to play a relatively secondary role in the genetic and biochemical networks that ultimately enable P. putida to endure environmental stresses. Instead, the main value of polyP could be ensuring a reservoire of energy during prolonged starvation. This is perhaps one of the reasons for polyP persistence in live systems despite its apparent lack of essentiality.

Ecosystem function enhanced by combining four functional types of plant species in intensively managed grassland mixtures: a 3‐year continental‐scale field experiment

SummaryA coordinated continental‐scale field experiment across 31 sites was used to compare the biomass yield of monocultures and four species mixtures associated with intensively managed agricultural grassland systems. To increase complementarity in resource use, each of the four species in the experimental design represented a distinct functional type derived from two levels of each of two functional traits, nitrogen acquisition (N2‐fixing legume or nonfixing grass) crossed with temporal development (fast‐establishing or temporally persistent). Relative abundances of the four functional types in mixtures were systematically varied at sowing to vary the evenness of the same four species in mixture communities at each site and sown at two levels of seed density.Across multiple years, the total yield (including weed biomass) of the mixtures exceeded that of the average monoculture in >97% of comparisons. It also exceeded that of the best monoculture (transgressive overyielding) in about 60% of sites, with a mean yield ratio of mixture to best‐performing monoculture of 1·07 across all sites. Analyses based on yield of sown species only (excluding weed biomass) demonstrated considerably greater transgressive overyielding (significant at about 70% of sites, ratio of mixture to best‐performing monoculture = 1·18).Mixtures maintained a resistance to weed invasion over at least 3 years. In mixtures, median values indicate <4% of weed biomass in total yield, whereas the median percentage of weeds in monocultures increased from 15% in year 1 to 32% in year 3.Within each year, there was a highly significant relationship (P < 0·0001) between sward evenness and the diversity effect (excess of mixture performance over that predicted from the monoculture performances of component species). At lower evenness values, increases in community evenness resulted in an increased diversity effect, but the diversity effect was not significantly different from the maximum diversity effect across a wide range of higher evenness values. The latter indicates the robustness of the diversity effect to changes in species' relative abundances.Across sites with three complete years of data (24 of the 31 sites), the effect of interactions between the fast‐establishing and temporal persistent trait levels of temporal development was highly significant and comparable in magnitude to effects of interactions betweenN2‐fixing and nonfixing trait levels of nitrogen acquisition.Synthesis and applications. The design of grassland mixtures is relevant to farm‐level strategies to achieve sustainable intensification. Experimental evidence indicated significant yield benefits of four species agronomic mixtures which yielded more than the highest‐yielding monoculture at most sites. The results are relevant for agricultural practice and show how grassland mixtures can be designed to improve resource complementarity, increase yields and reduce weed invasion. The yield benefits were robust to considerable changes in the relative proportions of the four species, which is extremely useful for practical management of grassland swards.

Orbitofrontal Dysfunction and Medication Overuse in Patients With Migraine

Orbitofrontal cortex (OFC) dysfunction and poor decision making have been described in patients with chronic migraine and medication overuse. These neurobiological underpinnings might explain dependency-like behaviors often described in this condition, such as loss of control over painkillers, high rates of relapse after detoxification, and compromised social functioning. We investigate whether the OFC impairment was a persistent trait in migraine, independent of clinical and affective features, a dynamic result of the need to cope with the increased pain and disability, or a temporary consequence of medication overuse. For this purpose, we compared 40 chronic migraineurs with medication overuse, 40 episodic migraineurs, and 40 matched healthy controls. The examination consisted of a clinical interview, Anxiety and Depression Hamilton Scales, Severity of Dependence Scale, and Migraine Disability Assessment questionnaire. A neuropsychological assessment of orbitofrontal function was made through the Iowa Gambling Task (IGT). Chronic migraineurs with medication overuse were followed for a year after detoxification. We found an impaired decision-making performance among chronic and episodic migraineurs that seems independent of the patients' clinical and affective status. Contrary to the psychiatric and clinical improvement shown 1 year after the detox, CM patients exhibited a persistent IGT deficit. No significant differences in OFC functioning were found between the CM patients who relapsed into medication overuse after detox and those who did not. The present findings suggest the presence of a persistent OFC dysfunction in migraine as a psychobiologic trait that is not influenced by the presence of medication overuse, the clinical severity of the disease, or the patient's affective status. Further studies are needed to elucidate the etiopathological role of OFC in migraine and medication overuse.

Correlation of G/A -22018 single-nucleotide polymorphism with lactase activity and its usefulness in improving the diagnosis of adult-type hypolactasia among North Indian children

Adult-type hypolactasia (AtH or lactase non-persistence) is the physiological decline in lactase activity that manifests in majority of the world's population after weaning. Recently, various single-nucleotide polymorphisms (SNPs) upstream of lactase gene (LCT) have been suggested to be associated with AtH or the lactase persistent trait in different human populations. C/T -13910 SNP was found be completely associated with AtH in Finnish population, and G/A -22018 SNP was found to be strongly, but not completely, associated with AtH. The aim of this study was to correlate G/A -22018 SNP with intestinal lactase activity in North Indian children. These children were also genotyped for C/T -13910 SNP. We also examined the differences in milk consumption and milk-related clinical symptoms in children with different genotypes of G/A -22018 and C/T -13910 SNPs. Intestinal biopsies were obtained from 231 children aged 2-16years undergoing routine endoscopy for various abdominal complaints. The biopsies were assayed for lactase, sucrase, and maltase activities and genotyped for G/A -22018 and C/T -13910 SNPs using restriction fragment length polymorphism and DNA sequencing analysis. There was a significant correlation between lactase activity and different genotypes of G/A -22018 SNP. Children with G/G -22018 genotype had low lactase activity. With a reference value of<10U/g protein (lactase activity) to be indicative of AtH, the sensitivity and specificity of genetic test based on G/A -22018 SNP was 94.4 and 94.1%, respectively. Furthermore, the consumption of milk was lower in children with G/G -22018 genotype. Flatulence was the only symptom significantly more frequent among the children with G/G -22018 genotype compared to those with G/A and A/A -22018 genotypes. However, most of the children with G/G -22018 genotype seem to tolerate small amounts of milk without any significant difference in gastrointestinal symptoms from those with G/A and A/A -22018 genotypes.

Longitudinal hypothalamic–pituitary–adrenal axis trait and state effects in recurrent depression

Hypothalamic-pituitary-adrenal (HPA)-axis hyperactivity has been observed in (recurrent) major depressive disorder (MDD), although inconsistently and mainly cross-sectional. Longitudinal studies clarifying state-trait issues are lacking. We aimed to determine whether HPA-axis (hyper)activity in recurrent MDD is: (I) reflecting a persistent trait; (II) influenced by depressive state; (III) associated with stress or previous episodes; (IV) associated with recurrence; and (V) influenced by cognitive therapy. We included 187 remitted highly recurrent MDD-patients (mean number of previous episodes: 6.3), participating in a randomized-controlled-trial investigating the preventive effect of additional cognitive therapy on recurrence. In an add-on two-staged patient-control and prospective-cohort design, we first cross-sectionally compared patients' salivary morning and evening cortisol concentrations with 72 age- and sex-matched controls, and subsequently longitudinally followed-up the patients with repeated measures after three months and two years. Patients had higher cortisol concentrations than controls (p<.001), which did not change by MDD-episodes during follow-up. HPA-axis activity had no relation with daily hassles or childhood life events. Cortisol concentrations were lower in patients with more previous episodes (p=.047), but not associated with recurrence(s) during follow-up. Finally, randomly assigned cognitive therapy at study-entry enhanced cortisol declines over the day throughout the two-year follow-up (p=.052). Our results indicate that remitted recurrent MDD-patients have a persistent trait of increased cortisol concentrations, irrespective of stress. In combination with our finding that patients' cortisol concentrations do not change during new MDD-episodes (and thus not represent epiphenomenal or state-effects), our results support that hypercortisolemia fulfills the state-independence criterion for an endophenotype for recurrent depression.

Influence of aripiprazole on the antidepressant, anxiolytic and cognitive functions of rats

Recent research has suggested that cognitive disorders are a persistent trait of mental illnesses such as schizophrenia. Cognitive deficits in the course of schizophrenia may be due to the disease and/or drug therapy, especially with old-generation drugs.Several clinical experiments have indicated the beneficial effects of new-generation antipsychotics on cognitive processes in patients treated for mental disorders.Aripiprazole is a new, atypical antipsychotic with a unique mechanism of action, which may have positive effects on cognitive functions.The aim of this study was to investigate the effects of aripiprazole on spatial memory in the Morris water maze and antidepressant activity in the Porsolt test. In addition, we examined whether aripiprazole had any side effects in the chimney test. The behavioral tests showed that aripiprazole improved spatial memory in rats and had antidepressant and anxiolytic effects after a single treatment; however, aripiprazole impaired motor coordination after repeated administration.We concluded that aripiprazole could be an effective antipsychotic for the treatment of patients with schizophrenia or bipolar disorder who have associated anxiety and cognitive deficits.

The Impact of Migrant-Hostile Discourse in the Media and Politics on Racioethnic Closure in Career Development in the Netherlands

Racioethnic inequality is a persistent trait of labour markets in countries that receive transnational migration flows. Little is known about the societal factors that influence the production of such inequality. Based on research among employees of the Dutch national tax administration, this article identifies the rise of a migrant-hostile discourse that has come to dominate Dutch politics and media since 2000 as an example of a societal factor that aggravates racioethnic closure in career advancement. It shows that tensions among colleagues triggered by public events that express this discourse fuel the career insecurities of migrant employees in particular. This insecurity has negative career consequences for them. The article argues that the study of racioethnic inequality in the labour markets of migrant-receiving countries needs to include a focus on the impact of (changes in) dominant discourses in the media and the political arena on migrants and migration.

A comprehensive approach to characterization of the nonlinearity of runoff in the headwaters of the Tarim River, western China

AbstractNonlinear characteristics of the runoff processes in the headwaters of the Tarim River were identified and evaluated using several selected methods, including wavelet analysis, correlation dimension, and R/S analysis. Time‐series of annual data describing runoff, average temperature, and precipitation from 1957 to 2005 were used to construct and test empirical models. The primary findings of this study were as follows: (1) The annual runoff of the headwaters are complex and nonlinear in nature, and they each presented periodic, nonlinear trends at the chosen time scales, chaotic dynamics, and long‐memory characteristics. (2) These nonlinear trends appeared to have resulted from the regional climatic changes that occurred during the study period. The periodicity of changes in runoff occurred on an approximately 25‐year cycle, which appeared to be correlated with temperature and precipitation cycles. In addition, the annual runoff exhibited a significant, positive correlation with the temperature and precipitation factors at the 4‐, 8‐, 16‐, and 32‐year temporal scales. (3) The correlation dimensions of the attractor derived from the runoff time series for the Hotan, Yarkand, and Aksu rivers were all greater than 3·0 and non‐integral, implying that all three rivers are dynamic chaotic systems that are sensitive to initial conditions, and that the dynamic modelling of their annual runoff requires at least four independent variables. (4) The computed Hurst exponents indicate that a long‐term memory characteristic exists in the annual runoff processes. However, there were some differences observed, with the Aksu and Yarkand rivers demonstrating a persistent trait, and the Hotan River exhibiting an anti‐persistent feature. Copyright © 2009 John Wiley &amp; Sons, Ltd.

Different from Himself: Hawthorne and the Masks of Masculinity

Different from Himself: Hawthorne and the Masks of Masculinity

Predictors of bruxism, other oral parafunctions, and tooth wear over a 20-year follow-up period: Gunnar E. Carlsson, Inger Egermark, Tomas Magnusson. J Orofac Pain 2003;17-50-7

Aims To analyze predictors of bruxism, other oral parafunctions, and tooth wear in a group of subjects who had been examined 20 years earlier. Methods Originally, 402 randomly selected 7-, 11-, and 15-year-old subjects were examined clinically and by means of a questionnaire. Twenty years after the first examination, 94% of the original group could be traced, and 320 (85%) completed and returned the questionnaire. Of the oldest group, 100 (81%) also underwent a clinical examination focusing on occlusal factors and function and dysfunction of the masticatory system. For analyses of predictors of some oral parafunctions and tooth wear registered at the 20-year follow-up, logistic regression was used with recordings at the first examination as independent variables. Results Subjective reports in childhood of bruxism (defined as tooth clenching during daytime and/or tooth grinding at night), clenching only, grinding at night only, nail biting, and/or other parafunctions were predictors of the same oral parafunctions 20 years later. There were different predictors of the 2 components of bruxism, daytime tooth clenching and tooth grinding at night. Postnormal occlusion (Angle Class II malocclusion) and tooth wear in childhood predicted increased tooth wear in adulthood. Subjects with nonworking-side interference had less anterior tooth wear than those without such interference. Conclusion Oral parafunctions in childhood may be a persistent trait in many subjects. Postnormal occlusion and tooth wear in childhood predicted increased anterior tooth wear 20 years later, whereas nonworking-side interference reduced the risk for such wear in 35-year-old subjects.