A pharmacotherapy approach to the treatment of ventricular tachycardia (VT) is frequently complicated by poor tolerance, persistent ICD shocks and impartial rhythm control. This can be burdensome in an elderly population who frequently have significant comorbidities complicating medical care. Catheter ablation for ventricular tachycardia has been increasingly employed to treat VT, however a paucity of data on the safety and outcomes of VT ablation in octogenarians exists. To examine the safety and outcomes of ventricular tachycardia ablation therapy in octogenarians. The data used was obtained from the National Inpatient Sample (NIS) database from 2016 to 2019. We identified patients ≥ 21 years old with VT as primary diagnoses and underwent ablation during index hospitalization. Patients were divided into 4 age subgroups 20-39, 40-59, 60-79 and ≥ 80 years old. Primary outcome was all-cause mortality and secondary outcomes were transfer to rehab, hospital length-of-stay and in-hospital complications. Univariate and multivariate logistic regression analyses were used to study the association between catheter ablation and primary and secondary outcomes. A total of 23,900 patients undergoing VT ablation were identified. Most patients were between ages of 50-69 years of age (60.3%), followed by 40-59 (25%), ≥ 80 (9.5%), and 20-39 (5.6%). No significant differences in complications including procedure-related pericardial effusion, pericarditis, tamponade, stroke, hemorrhage, or respiratory failure were seen between all age groups. Similarly, no significant differences in hospital length of stay were appreciated across all ages. However, mortality rates were significantly higher in octogenarians (4.2%), compared to those between 60-79 years old (3.2%), 40-59 years (1.5%) and 20-39 years (2.3%) (p-value 0.023). Rehab transfer was also significantly higher in the elderly (p-value <0.001). In this large, real-world database study, we found no significant differences in procedure related complications or hospital length of stay across all age groups undergoing VT ablation. However, in-hospital mortality rates and transfer to rehab were significantly higher in octogenarians compared to younger subgroups. Despite procedural safety, a decision to pursue VT ablation in octogenarians must be carefully weighed against modest increased risks of mortality in this delicate population.