Permanent Shift Research Articles

Association of sleep disturbance with shift work, occupational stress, and musculoskeletal pain in Chinese public hospital emergency workers: A multicentre cross-sectional study

ABSTRACT Poor sleep, which is reportedly prevalent among healthcare professionals, could lead to various detrimental consequences. This study aimed to investigate the sleep quality of individuals working in emergency departments of public hospitals in China and explore the potential factors influencing sleep disturbance. A self-administered questionnaire was completed by 7688 emergency workers from 147 public hospitals in Shandong, China. Log-binomial regression analysis was performed to explore the relationship of sleep disturbance with possible influencing factors, including individual and work characteristics, occupational stress, shift work, and musculoskeletal pain. The participants’ mean Pittsburgh Sleep Quality Index score was 9.6 ± 4.8, with 5341 (69.5%, 68.2–70.7%) of them experiencing sleep disturbance. The sleep quality was poorer in doctors (10.2 ± 5.1, 71.0%, 69.0–73.0%) than in nurses (9.2 ± 4.5, 68.6%, 67.0–70.1%), and poorer in those working in secondary (9.9 ± 4.5, 70.2%, 68.0–72.3%) and tertiary (12.2 ± 4.9, 77.5%, 75.3–79.7%) hospitals than in primary hospitals (8.0 ± 4.1, 64.6%, 62.6–66.6%). High prevalence of sleep disturbance was significantly associated with shift work, occupational stress, musculoskeletal pain, fewer breaks in a work shift, and less exercise during leisure time, after adjusting for confounding variables. Sleep disturbance occurred in emergency workers in the following order: two-shift rotation > three-shift rotation > permanent night shift > permanent day shift. Emergency workers in public hospitals in China had poor sleep quality and commonly experienced musculoskeletal pain. Urgent and comprehensive measures are needed to combat these issues.

Abstract P5-06-08: Triple-negative breast cancer CAFs induce a metastatic phenotype in MCF-7 cells via the SDF-1/CXCR4 axis

Abstract Background: Metastatic disease is the foremost cause of breast cancer (BC) related mortality in women. One of the crucial challenges in reducing metastasis-related mortality is in identifying and understanding why certain BCs metastasize and recur. Although cancer cell-intrinsic factors are a key determinant in BC metastasis, host-intrinsic factors like the cells of the tumor microenvironment (TME), such as cancer-associated fibroblasts (CAFs) are what might be driving certain BCs to metastasize and recur. We recently showed that CAFs from the primary (TME) enter into circulation as cCAFs, form heterotypic clusters with tumor cells, and arrive at metastatic sites. This interaction between CAFs and tumor cells is crucial in furthering the metastatic cascade. However, the functional heterogeneity of the different CAF phenotypes and how that impacts BC metastasis is unknown. Stromal derived factor-1 (SDF-1/CXCL12) is an important chemokine that is known to be involved in promoting tumor cell invasion and metastasis. In this study, we examine the functional differences between CAF isolated from different molecular subtypes of BC. Furthermore, we elucidate the role of CAF secreted SDF-1 as being one of the mechanisms by which a subset of CAF cells permanently reprograms poorly-metastatic MCF-7 cells to augment EMT-driven genes and become metastatic in vivo. Methods: We used primary CAF cell lines derived from BCs of different molecular subtypes and examined their global gene expression profiles using RNAseq. We used NSG mice xenografted with MCF-7 BC cells and primary CAF cells to evaluate the contribution of two different CAF phenotypes in promoting BC progression and metastasis. We developed dissociated tumor cell lines from CAF co-injected MCF-7 xenografts to determine the molecular changes that CAFs impart to MCF-7 cells in vivo. Using limiting dilution tumor xenograft assays and gene expression profiles we examined the molecular pathways, BC stemness markers, and tumor-initiating capacity of the dissociated tumor cell lines. By long-term SDF-1 treatment of MCF-7 cells in vitro and using these cells in various RNASeq, in vitro, and in vivo assays we determined the role of SDF-1 in altering the phenotype of MCF-7 cells. Results: We found that CAFs from different molecular subtypes have a differential effect on tumor initiation, progression, and metastasis in xenograft assays. We also found that a subset of CAFs has the ability to make the poorly-metastatic MCF-7 cells metastatic in vivo. We also found that this subset of CAF cells has a higher expression of SDF-1 and the tumors formed with the co-injection of MCF-7 cells with this subset of CAF cells are enriched in cancer stem cell-like metastasis initiating cells. We also found that upon serial transplant, the tumors formed by CAF-reprogramed MCF-7 cells have a gene expression profile that shows enrichment for EMT-driven genes and these tumors are robustly metastatic. Furthermore, we found that the SDF-1/CXCR4 axis is one of the critical mechanisms by which this subset of CAF cells permanently reprograms the phenotype of the MCF-7 cells. Conclusions: CAFs are a highly heterogeneous population of cells in the breast TME. This study examines the contribution of the functional heterogeneity of the CAF cells in BC metastasis. We have found that a unique subset of CAF cells has the ability to reprogram a poorly metastatic BC cell to not only become metastatic but induce a permanent EMT-driven phenotypic shift in the BC cells. SDF-1 may be one of the mechanisms that drive this CAF-induced change and understanding the CAF functional landscape and its role in BC metastasis might be crucial to developing new therapeutic modalities to abrogate BC metastasis. Citation Format: Utsav Sharma, Jun Sun, Kelsie Medina-Saenz, Susan Bare, Philip Miller, Manuel Picon-Ruiz, Joyce Slingerland, Dorraya El-Ashry, Marc Lippman. Triple-negative breast cancer CAFs induce a metastatic phenotype in MCF-7 cells via the SDF-1/CXCR4 axis [abstract]. In: Proceedings of the 2021 San Antonio Breast Cancer Symposium; 2021 Dec 7-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2022;82(4 Suppl):Abstract nr P5-06-08.

Impact of night and shift work on metabolic syndrome and its components: a cross-sectional study in an active middle-to-older-aged population-based sample

ObjectivesTo examine the effects of work schedules on metabolic syndrome and its components in active middle-to-older-aged workers.MethodsA cross-sectional analysis including middle-to-older-aged active workers from the population-based CoLaus|PsyCoLaus study (Lausanne, Switzerland)...

Climate-Driven High Primary Production and Contrasting Export Production in the Eastern North Pacific Subtropical Gyre

The eastern North Pacific subtropical gyre (NPSG) contributes significantly to global primary production (PP) and export production (EP). In this study, we have investigated the impact of the North Pacific gyre oscillation (NPGO) mode on the temporal changes in the relationship between PP and EP in the eastern NPSG, using long-term time series of oceanographic observations at Station ALOHA. The positive NPGO phases (N2+: 1998–2004, N4+: 2007–2013), exhibiting a deeper mixed layer depth (MLD), coincided with high PP. Moreover, the N2+ phase showed high EP, associated with an increase in the nano-sized phytoplankton group, and inorganic and organic nitrogen-to-phosphorus ratios. However, multiple physical and biogeochemical factors, such as thermocline depression, increase in pico-sized phytoplankton groups, smallest-sized mesozooplankton, and heterotrophic bacteria, have induced low EP during the N4+ phase, despite deep MLD and increased PP conditions. Enhanced stratification under prolonged warming indicates that the surface eastern NPSG may experience a permanent shift toward small cells.

Social jetlag and sleep debts are altered in different rosters of night shift work

Night and shift work are suspected to cause various adverse effects on health and sleep. Sleep deprivation through shift work is assumed to be compensated on free days. So far it is not clear how different shift systems and shift lengths affect sleep structure on work and free days. Especially working night shifts disrupts the circadian rhythm but also extended working hours (12h) might affect sleep characteristics. Hitherto, the magnitude of sleep debt, social jetlag, and Locomotor Inactivity During Sleep (LIDS) in different shift systems is unknown. Here, we investigated the impact of five different shift rosters on sleep in 129 industrial workers from Germany. Permanent night work with multiple shift systems with and without night shifts and with different shift lengths were compared. Wrist-activity was monitored over 28 days revealing sleep on- and offsets as well as LIDS as proxy for sleep quality. Overall, 3,865 sleep bouts comprising 22,310 hours of sleep were examined. The mean daily age-adjusted sleep duration (including naps) was 6:43h and did not differ between shift workers of different rosters. However, sleep duration on workdays was particularly low in rotational shift systems with 12h-shifts (5:00h), while overall sleep debt was highest. Shift workers showed a median absolute social jetlag of 3:03h, which differed considerably between shift types and rosters (p<0.0001). Permanent night workers had the highest social jetlag (5:08h) and latest mid-sleeps on workdays and free days. Sleep quality was reduced in permanent night shift workers compared with shift workers in other rosters and differed between daytime and nighttime sleep. Shift work leads to partial sleep deprivation, which particularly affects workers in 12h-shifts and permanent night shifts. Working these shifts resulted in higher sleep debts and larger absolute social jetlag whereas sleep quality was especially reduced in permanent night shift workers compared with shift workers of other rosters.

Working permanent night shifts and insomnia among nurses

Working permanent night shifts and insomnia among nurses

The COVID-19 outbreak and its impact on business establishments: a study on challenges and strategic approaches

The Management Association of the Philippines (MAP) commissioned the School of Economics of the University of Asia and the Pacific (UA&amp;P) to conduct a study aimed at understanding the impact of the COVID-19 outbreak on various industry sectors and to draw possible policy measures for both government and private institutions to help the affected sectors deal with the pandemic’s negative effects and gradually return to stable business operations. An online survey of pre-selected thirty-three (33) representatives from key priority sectors which recorded sharp contractions in the first two quarters of 2020 and which had a share to GDP of above 1 percent was conducted. To validate the survey results, stakeholder interviews were also conducted with more than 10 firms via the zoom video conferencing platform. The survey results confirmed the negative impact of the pandemic at the firm-level (i.e., decrease in employee compensation, decline in headcount, loss of revenue and other liquidity crunches, prolonged collection periods, problems in logistics, delayed or cancelled projects and disrupted supply chains and access to labor; among others). Some have had to close branches or altogether cease operations. The sudden and likely permanent shift towards digitization of operations has disrupted operations and exerted pressure to digitally transform business operations in order to survive in the so-called “new normal.” Moreover, this requires investments in equipment and training. Additional costs and investments are also needed to meet health and safety standards and protocols. Thus, required assistance commonly cited by firms were loans, subsidies, and tax relief In the short term, the national government must restore consumer confidence and deploy its fiscal powers to stimulate aggregate demand. With assistance, business can invest in platforms and meeting health and safety protocols for workers and customers to return to work and patronize their business, whether on site or online. Resuscitating the economy is not solely the responsibility of government. It also requires solidarity and coordinated response from the private sector. Over the long term, both government and business must build more resilient organizations and strategies. This would include adopting digital transformation by both private and public sectors for a more nimble and agile economy. Business may also revisit the concept of “coopetition”. The interconnectedness of each industry calls for a more collaborative approach among businesses. When firms who have been negatively affected by the pandemic recover, this can also increase the rate at which the economy bounces back.

Bank Branches and COVID-19: Where are Banks Closing Branches during the Pandemic?

&lt;ns3:p&gt;In the decade prior to the COVID-19 pandemic, bank branches were closing at a steady rate. Additionally, households with a bank account increasingly adopted mobile or online banking for at least a portion of their banking needs. As COVID-19 dramatically changes the desire and willingness for consumers to have in-person interactions, it may accelerate both of these trends and lead to a permanent shift in how people access financial services.&lt;/ns3:p&gt;

Інформаційна технологія прогнозування фінансових результатів страхових компаній

The purpose of time series modelling is to predict future indicators based on the study and analysis of past and present data. Various time series methods are used for forecasting. The article uses econometric extrapolation research methods. Analyzed scientific works are related to extrapolation methods for forecasting time series. The dynamics of the financial formation related to results of Ukrainian insurance companies by the types of their activities have been analyzed. The main factors that determine the effectiveness are determined. It was found that the most rational approach to short-term forecasting of the financial results of insurers is the use of exponential smoothing. The optimal parameters are selected for the model of exponential smoothing of the first and second order by the method on the grid. The following indicators of the quality of the model were used: the mean value of the standard deviation of the model error to the actual data, Theils coefficient of discrepancy, mean absolute percentage error MARE. The net financial result of the activities of Ukrainian insurers was predicted, the lower and upper bounds of the forecast for 2021 for a reliability level of 0.95. To predict the net financial result of the activities of Ukrainian insurers, statistical data for 10 years from 2011 to 2020 were used, the financial results of the main (insurance and other operating) activities before tax, the results of financial activities before tax, the financial results of other ordinary activities (extraordinary events) before tax, income tax. The prototype of the software module for predicting the financial performance of insurance companies was developed in Statistica and Excel. Forecasting results based on the use of econometric modelling make it possible to identify permanent positive shifts in the domestic insurance market and the activities of insurers on it; to confirm the effectiveness of the adopted strategic and tactical financial decisions of insurance companies; to increase the efficiency of insurers management based on the results of quantitative determination the degree of influence of each factor on the formation of the financial results related to their activities; to identify trends in the development of the situation in the future, to more accurately form a set of measures to maximize profits and minimize costs of insurance companies to ensure guarantees of reliable insurance protection and satisfy the interests of their owners. Keywords: financial results; insurance companies; net financial result; exponential smoothing; time series; econometric forecasting methods.

Gravitational-wave memory effects in Brans-Dicke theory: Waveforms and effects in the post-Newtonian approximation

Gravitational-wave (GW) memory effects produce permanent shifts in the GW strain and its time integrals after the passage of a burst of GWs. Their presence is closely tied to symmetries of asymptotically flat spacetimes and fluxes of conserved charges conjugate to these symmetries. While the phenomenology of GW memory effects is well understood in general relativity (GR), it is less well understood in the many modifications to GR. We recently computed asymptotically flat solutions, symmetries, conserved quantities, and GW memory effects in one such modified theory: Brans-Dicke theory. In this paper, we apply our results from this earlier work to compute the GW memories from compact binaries in the post-Newtonian (PN) approximation. In addition to taking the PN limit of these effects, we work in the approximation that the energy and angular momentum losses through scalar radiation are small compared to the energy and angular momentum losses through (tensor) GWs. We focus on the tensor (as opposed to scalar) GW memory effect, which we compute through Newtonian order, and the small differences induced by scalar radiation at this order. Specifically, we compute the nonlinear parts of the tensor displacement and spin GW memory effects produced during the inspiral of quasicircular, nonprecessing binaries in Brans-Dicke theory. Because the energy radiated through the scalar dipole moment appears as a -1 PN order-effect, then in this approximation, the displacement memory has a logarithmic dependence on the PN parameter and the spin memory has a relative -1 PN-order correction; these corrections are ultimately small because they are related to the total energy and angular momentum radiated in the scalar field, respectively. At Newtonian order, the scalar radiation also gives rise to a sky pattern of the memory effect around an isolated source that differs from that of the memory effect in GR.

Timing and Composition of Last Meal before Bedtime Affect Sleep Parameters of Night Workers.

Night workers tend to eat irregularly, both in terms of meal times and composition. The disruption in energy metabolism caused by inappropriate eating habits can negatively affect the sleep quality of these individuals. The objectives of this study were to determine the interval between the last meal and bedtime and its relationship with both diurnal and nocturnal sleep parameters, as well as to evaluate the association of the adequacy of this meal with sleep parameters. The analyses were carried out for a usual sleep routine on a workday and a day off. This cross-sectional study was part of a controlled, randomized, double-blind, crossover clinical trial. The sample comprised 30 female nursing professionals who worked permanent night shifts of 12 × 36 h. Timing and composition of the last meal were obtained from food diaries, and sleep parameters were collected via actigraphy. On multiple linear regression analysis, every hour decrease in the interval between the last meal and sleep onset there was an increase of 0.39 h on diurnal sleep duration. Regarding food intake, every 1 g of fat and 1 g of carbohydrate consumed was associated with an increase in diurnal sleep onset latency of 0.13 h and 0.02 h, respectively. These findings suggest that both timing and composition of the last meal before bedtime may be potential key factors for good diurnal and nocturnal sleep among night-shift workers.

Stability of the threshold voltage in fluorine-implanted normally-off AlN/GaN HEMTs co-integrated with commercial normally-on GaN HEMT technology

Fluorine ion migration in normally-off AlN/GaN HEMTs fabricated by fluorine ion plasma implantation technology is evidenced. Devices under test are co-integrated into the OMMIC commercial D006GH/D01GH MMIC process, providing fluorine-free normally-on HEMTs. Gate reverse bias step-stress experiment at a drain fixed voltage of 0 V, carried out as well on normally-on ones as on normally-off ones, shows a permanent negative shift in the threshold voltage Vth of normally-off devices only. Vth degradation is starting at a VGS,stress of −8 V, with a negative shift from 0 V to −0.4 V at VGS,stress = −30 V, while the transconductance gm and gm,max remains unchanged prior to breakdown that occurred at VGS,stress ranging between −26 and −32 V. Since the positive threshold voltage of these devices is induced by F-ions dose and position, the above result suggests a possible drift of F-ions away from the 2DEG channel. A field-assisted migration mechanism of fluorine ions is proposed and supported by the absence of Vth degradation in fluorine-free normally-on devices.

Does gender matter for the unemployment hysteresis effect among Asian countries?

PurposeThis study aims to examine the unemployment hysteresis effects from the perspective of the heterogeneity of genders within Asian countries.Design/methodology/approachThe authors use the annual unemployment rate dataset of 12 Asian countries ranging from 1991–2020. Traditional unit root tests are initially employed to investigate the unemployment hysteresis effect. Considering the structural break and cross-section dependence problems, the sequential panel selection method (SPSM) and the Kapetanios–Snell–Shin (KSS) panel unit root test with Fourier functions have proven to be more applicable.FindingsThe empirical results indicate that the unemployment rate is stationary in most Asian regions for both females and males, which confirms the mean reversion process of the natural unemployment hypothesis. This suggests that these countries' unemployment rates are flexible to quickly revert to its long-run equilibrium determined by the labor markets. However, only the female unemployment rate in Pakistan and Nepal and adult female unemployment rates in these two economies present non-stationary series. In line with the unemployment hysteresis effect, it means shocks will leave a permanent impact on their labor market.Practical implicationsOn the one hand, in most of the Asian countries, it can be inferred that the trade-off between inflation and unemployment is temporary because the natural unemployment hypothesis holds. Therefore, policymakers may consider using monetary policy as a tool to control inflation and stimulate growth during a recession. Such policy measures should not have a long-run impact on unemployment or cause a permanent shift in the natural unemployment rate. On the other hand, the government should implement active labor protective programs such as education or training schemes, job search assistance programs and maternity protection, especially for female adults, to reduce the negative shocks in the economic downturn, which is beneficial for them away from being long-term unemployed. It is also necessary to improve the labor unions to reduce the discrimination between female and male labors.Originality/valueThis paper innovatively concentrates on the heterogeneity performances between genders about the unemployment hysteresis effect within Asian countries. Furthermore, taking into account the age-specific characteristics, the youth and adult unemployment rates have been investigated. Additionally, the approximation of bootstrap distribution and the advanced panel KSS unit root test with a Fourier function are employed. Thereby, targeted policies for the government can be applied to reduce the discrimination and negative shocks on female adults in the labor market.

Long-term night shift work is associated with the risk of atrial fibrillation and coronary heart disease.

The aim of this study was to test whether current and past night shift work was associated with incident atrial fibrillation (AF) and whether this association was modified by genetic vulnerability. Its associations with coronary heart disease (CHD), stroke, and heart failure (HF) were measured as a secondary aim. This cohort study included 283 657 participants in paid employment or self-employed without AF and 276 009 participants free of CHD, stroke, and HF at baseline in the UK Biobank. Current and lifetime night shift work information was obtained. Cox proportional hazard models were used. Weighted genetic risk score for AF was calculated. During a median follow-up of 10.4 years, 5777 incident AF cases were documented. From 'day workers', 'shift but never/rarely night shifts', and 'some night shifts' to 'usual/permanent night shifts', there was a significant increasing trend in the risk of incident AF (P for trend 0.013). Usual or permanent night shifts were associated with the highest risk [hazard ratio (HR) 1.16, 95% confidence interval (CI) 1.02-1.32]. Considering a person's lifetime work schedule and compared with shift workers never working nights, participants with a duration over 10 years and an average 3-8 nights/month frequency of night shift work exposure possessed higher AF risk (HR 1.18, 95% CI 0.99-1.40 and HR 1.22, 95% CI 1.02-1.45, respectively). These associations between current and lifetime night shifts and AF were not modified by genetic predisposition to AF. Usual/permanent current night shifts, ≥10 years and 3-8 nights/month of lifetime night shifts were significantly associated with a higher risk of incident CHD (HR 1.22, 95% CI 1.11-1.35, HR 1.37, 95% CI 1.20-1.58 and HR 1.35, 95% CI 1.18-1.55, respectively). These associations in stroke and HF were not significant. Both current and lifetime night shift exposures were associated with increased AF risk, regardless of genetic AF risk. Night shift exposure also increased the risk of CHD but not stroke or HF. Whether decreasing night shift work frequency and duration might represent another avenue to improve heart health during working life and beyond warrants further study.

Close encounters of the worst kind: reforms needed to curb coral reef damage by recreational divers

Intentional and unintentional physical contact between scuba divers and the seabed is made by most divers and multiple times per dive, which often results in damage to corals and other marine life. Current efforts to reduce reef contacts (e.g., voluntary dive operator recognition programs and voluntary dive standards) can be effective, but lack sufficient incentive structures for long-term compliance. In their current capacity, these programs fail to reduce reef contacts to tolerable levels. Regulatory policies can facilitate pervasive and permanent shifts in human behavior, but have been underutilized to change unsustainable underwater norms. Most coral reefs open to recreational diving lie within territorial waters of individual countries, and many already have existing forms of protection with legislation that can be easily modified. Successful policy precedents in Marine Protected Areas (e.g., bans on underwater glove use) and elsewhere (e.g., anti-smoking laws in public spaces and legislation enforcing seat belt use) demonstrate the largely untapped potential of using effective governance to change destructive diving norms for good. To reduce intentional reef contacts, policy-makers can enact regulations in MPAs directly banning all contact between divers and the seabed. To reduce unintentional contacts, policy-makers can create policy safeguards that preempt such occurrences (e.g., requiring divers to keep a certain distance from the seabed). Crucially, such policies will need accompanying formal and informal enforcement measures that are equitable, effective, and efficient to motivate compliance and effect lasting behavior change. Having a robust, well-enforced, regulatory framework to tackle both types of reef contacts lends credence to the efforts of existing conservation programs, and is key to permanently changing divers’ underwater attitudes and fostering sustainable scuba diving behavior to the benefit of all.

Will Disabled Workers Be Winners or Losers in the Post-COVID-19 Labour Market?

Workplace inflexibility contributes to the higher rates of job loss and unemployment experienced by disabled people. Prior to the COVID-19 pandemic, many countries already had significant disability employment gaps. Based on evidence from previous recessions, the global recession resulting from the pandemic is likely to have a severer and longer-lasting impact on the employment of disabled workers compared with non-disabled workers. In the UK, there is already evidence that the disability employment gap has widened since the pandemic. On the other hand, the pandemic initiated increased access to home-working, a change in working arrangements that may prove beneficial to disabled workers employed in desk-based roles. Home-working can increase the accessibility of employment and support work retention for disabled workers, yet pre-pandemic many employers had withheld it. Studies of employees’ and employers’ experiences of home-working during the pandemic have indicated a desire to retain access to home-working in the future. A permanent cultural shift to increased access to home-working would help address the disability employment gap for desk-based workers. However, disabled workers are over-represented in jobs not conducive to home-working, and in sectors that have been hardest hit by business closures during the pandemic, so the position of many disabled workers is likely to remain precarious.

EDITORIAL. EMERGENCY REMOTE EDUCATION: METHODOLOGICAL, TECHNOLOGICAL, ORGANIZATIONAL AND POLICY ISSUES

EDITORIAL. EMERGENCY REMOTE EDUCATION: METHODOLOGICAL, TECHNOLOGICAL, ORGANIZATIONAL AND POLICY ISSUES

The scope of exclusionary public response to the European refugee crisis

AbstractWe know from previous research that an exclusionary reaction in public opinion is likely following a sudden and large‐scale influx of refugees of the sort experienced in many European countries in 2015. Yet, we know much less about the scope of these expected reactions. This article makes a conceptual and empirical contribution to the analysis of the scope of exclusionary reactions following a refugee crisis. Conceptually, we distinguish between three scope dimensions: substantive reach, duration and politicization. Empirically, we evaluate each of the scope dimensions using seven‐wave panel‐data collected before, during and after the large‐scale influx of refugees to Norway. We find that the expected exclusionary reaction (a) spilled over to opinion about immigration broadly speaking; (b) endured in that it lasted long after the situation in Norway had been brought under control; (c) encompassed voters of all political stripes. Nevertheless, we also document an important limitation to the scope of the reaction: The sudden influx of refugees to Norway did not cause a permanent shift in public opinion. Approximately two years after the situation had been brought under control, opinion about both refugee rights and immigration generally had reverted back to pre‐crisis baseline levels. Interestingly, the conceptual and empirical analysis suggests that public opinion dynamics following a sudden and large‐scale influx of refugees is similar to that found in response to other forms of large national or international crises.

Controlled and permanent induced Fermi shifts and upwards band bending in ZnO nanorods by surface stripping with argon bombardment

Optimised ZnO nanorod characteristics are essential for novel devices to operate efficiently, especially shifting the n-type nature towards intrinsic or p-type. The effects of argon bombardment for varying amounts of time on the surface chemistry and Fermi level of ZnO nanorods have been studied using XPS. Bombardment at 5 keV removed surface contamination caused by amorphous carbon and OH−, H2O and C-O groups. The bombardment also causes the O1s, Zn2p and valence band to shift to lower binding energies, indicating a shift towards intrinsic behaviour. Bombardment time can be used to effect a shift of up to 0.8 eV, and this shift remains after the nanorods were re-contaminated by exposure to ambient conditions for 28 days. These results indicate that argon bombardment can permanently shift the n-type nature of ZnO to intrinsic for use in novel devices.

Telehealth Strategies to Support Patients and Families Across the Cancer Trajectory.

Effective delivery of cancer care via telehealth requires a planned care system that accounts for myriad patient, provider, and practice/cancer center resources before, during, and after the care episode. Telehealth is broadly defined as a method to have virtual, bidirectional communication between patients and providers. Telehealth can include methods such as audio-only, video-consultation, and tele-monitoring, which can occur in a synchronous, asynchronous, or blended format. The purpose of this review is to present common foundational principles for providing clinical cancer care via telehealth, followed by an overview of three distinct examples of comprehensive telehealth programs that have been developed to meet the needs of patients and families across the cancer trajectory, including survivorship, rehabilitation, and palliative care phases. The programs described are exemplars that were developed and implemented prior to the coronavirus pandemic, so they reflect many years of planning and evidence. Lessons learned include the need for ongoing patient support, clinician training, and cancer health system/practice programmatic considerations such as billing, scheduling, reimbursement, software, and hardware/platform security. Although the COVID-19 pandemic produced an explosive shift in regulations and implementation, sustainability of these changes may not be long-term. Nevertheless, a permanent shift in cancer care to include telehealth is likely here to stay.