Periodontal Disease In Pregnancy Research Articles

Periodontal disease in polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) and periodontal disease (inflammatory diseases of the tissues around teeth) are common disorders associated with diabetes and cardiometabolic risk. Comprehensively examining the periodontal status in PCOS, this study suggests that the susceptibility for periodontal disease may significantly increase in patients with PCOS compared with healthy young women, and that local/periodontal oxidant status appears to be affected in PCOS.

Periodontal disease in pregnancy is a risk factor for preeclampsia

Many recent studies have evaluated the relation between periodontitis and pregnancy complications. This study aimed to examine the association between preeclampsia and periodontitis in Indian women. A total of 130 pregnant women were enrolled between 26-32 weeks of gestation. Oral health examinations were performed at recruitment and again within 48 hours of delivery to determine the presence and/or progression of periodontitis in all subjects. Pocket depth, clinical attachment loss (CAL), and gingival index were measured in all subjects. There was significant (p < 0.05) difference between the preeclampsia and normotensive groups in the distribution of periodontitis both at recruitment and after delivery. Multiple logistic regression demonstrated that periodontitis both at enrolment (OR = 5.78, 95% CI 2.41-13.89) as well as within 48 hours of delivery (OR = 20.15, 95% CI 4.55-89.29), may be associated with an increased risk of preeclampsia.

Treatment of localized periodontal disease in pregnancy does not reduce the occurrence of preterm birth: results from the Periodontal Infections and Prematurity Study (PIPS)

The purpose of this study was to test whether treating periodontal disease (PD) in pregnancy will reduce the incidence of spontaneous preterm delivery (SPTD) at < or = 35 weeks of gestation. A multicenter, randomized clinical trial was performed. Subjects with PD were randomized to scaling and root planing (active) or tooth polishing (control). The primary outcome was the occurrence of SPTD at <35 weeks of gestation. We screened 3563 subjects for PD; the prevalence of PD was 50%. Seven hundred fifty-seven subjects were assigned randomly; 378 subjects were assigned to the active group, and 379 subjects were assigned to the placebo group. Active treatment did not reduce the risk of SPTD at <35 weeks of gestation (relative risk, 1.19; 95% confidence interval [CI], 0.62-2.28) or composite neonatal morbidity (relative risk, 1.30; 95% CI, 0.83-2.04). There was a suggestion of an increase in the risk of indicated SPTD at <35 weeks of gestation in those subjects who received active treatment (relative risk, 3.01; 95% CI, 0.95-4.24). Treating periodontal disease does not reduce the incidence of SPTD.

Periodontal disease in pregnancy is a risk factor for preeclampsia

Periodontal disease in pregnancy is a risk factor for preeclampsia

192: Periodontal disease in pregnancy: does it affect neonatal outcome?

192: Periodontal disease in pregnancy: does it affect neonatal outcome?

Treatment of Periodontal Disease in Pregnancy Reduces Preterm Birth?

Treatment of Periodontal Disease in Pregnancy Reduces Preterm Birth?

5: Screening and treating periodontal disease in pregnancy does not reduce the incidence of preterm birth: Results from the PIPS study

5: Screening and treating periodontal disease in pregnancy does not reduce the incidence of preterm birth: Results from the PIPS study

The relationship between maternal periodontitis, adverse pregnancy outcome and miscarriage in never smokers

It has been postulated that associations between periodontal disease and systemic conditions may be because of the confounding effects of smoking. In addition, studies of this type rarely investigate the adverse pregnancy outcome of miscarriage. The aim of this prospective study was to investigate a relationship between periodontal disease in pregnancy and subsequent adverse pregnancy outcomes in a population of never smokers. Pregnant women were recruited at 12 weeks gestation. Demographic, behavioural and medical data were collected. A periodontal examination was performed and data on each subjects' pregnancy outcome were collected. A total of 1793 women reported never previously smoking. Of these, 7.3% had a pre-term birth and 0.9% a late miscarriage. As expected in this population, we found no associations between poorer periodontal health and either pre-term birth or low birth weight (LBW). In contrast, the subjects who experienced a late miscarriage had a higher mean probing depth at mesial sites compared with the subjects that gave birth at term (2.69 mm versus 2.41 mm, p=0.006). There was an association between some measures of periodontal disease and late miscarriage; however, there was no association between periodontitis and pre-term birth or LBW in this population.

Risk factors for periodontal disease in pregnancy

Risk factors for periodontal disease in pregnancy

Doença periodontal na gravidez e baixo peso ao nascer

Justificativa: Sabe-se, de longa data, que infecções dento-gengivais podem ter repercussões orgânicas a distância. Recentemente, foi sugerido que a doença periodontal na gravidez seja uma causa determinante de baixo peso ao nascer. Objetivo: Avaliar a influência da doença periodontal na gravidez sobre o peso de nascimento dos recém-nascidos. Pacientes e Métodos: Mães de recém-nascidos (RNs) com peso < 2500 gramas foram selecionadas na forma de amostra de conveniência (Grupo I - GI; n=13). Para cada mãe do GI, era selecionada, como controle, a mãe do próximo recém-nascido (RN) a termo, com peso > 2500 g (Grupo II - GII; n=13). As mães eram examinadas por um periodontista não informado do peso da criança, o qual utilizou uma sonda milimetrada para medir a perda de inserção do osso alveolar. Os índices de extensão (IE) e severidade (IS) da doença periodontal foram determinados usando-se as fórmulas descritas por Carlos et al. Resultados: Ambos os grupos de mães eram similares no que se refere a idade, paridade, raça, estatura, nutrição, tabagismo, uso de álcool, situação socioeconômica, pré-natal, rotura prematura de membranas, corioamnionite, bacteriúria, placenta prévia, descolamento de placenta, hipertensão prévia, pré-eclampsia e cardiopatia. As características dos recém-nascidos eram as seguintes: peso ao nascer - GI = 1804+675 g x GII = 3030 ± 516 g; idade gestacional (DUM) - GI = 33 ± 5 sem. x GII = 39 ± 2 sem.; tempo em UTI - GI = 128 dias x GII = 0 dias. O IE médio foi de GI = 89,788 ± 18,355 x GII = 72,420 ± 20,717; P =0,033. O IS médio foi de GI = 1,377 ± 0,626 x GII = 0,754 ± 0,413; (“Odds ratio” - OR = 18,3; IC95%: 2,5 a 133,3; P =0,006). Após ajuste para diversos fatores de risco para baixo peso incluindo fumo, estatura materna, bacteriúria e hipertensão prévia, o OR do IS caiu para 7,2 (0,4 a 125,4; P =0,176). Conclusões: A análise multivariada mostrou uma forte associação entre doença periodontal, marcada pelo escore IS, e baixo peso ao nascer. Os dados sugerem a possibilidade de que a doença periodontal na gravidez seja um fator de risco para o nascimento com baixo peso.

Periodontal disease in pregnancy and low birth weight

OBJECTIVE: Recently, it has been suggested that periodontal disease during pregnancy could have a causal relationship with low weight at birth. Our objective was to evaluate the influence of periodontal disease during pregnancy on the birth weight of newborn infants. METHODS: Mothers who gave birth to low-birth-weight infants were randomly selected (Group 1 - G1; n=13). Immediately after inclusion of each mother in group 1, the mother of the next term newborn with birth weight of > 2,500 g (Group 2 - G2; n=13) was included as control. Mothers were examined by a periodontist who was not informed of the group the child belonged to. A probe was used to measure attachment loss of the alveolar bone. The extension index (EI) and severity index (SI) of the periodontal disease were determined. RESULTS: Both groups of mothers were similar in terms of maternal age, parity, color of skin, height, nutrition, smoking, drinking, socioeconomic status, prenatal examinations, premature rupture of membranes, chorioamnionitis, bacteriuria, placenta previa, abruptio placentae, previous hypertensive disease, preeclampsia, and heart disease. The characteristics of the newborns were: birth weight - G1 = 1,804 -/+ 675 g x G2 = 3,030 -/+ 516 g; gestational age - G1 = 33 -/+ 5 weeks x G2 = 39 -/+ 2 weeks; length of stay in the neonatal intensive care unit (NICU) - G1 = 128 days x G2 = 0 days. Average EI: G1 = 89.788 -/+ 18.355 x G2 = 72.420 -/+ 20.717; p=0.033. Average SI: G1 = 1.377 -/+ 0.626 x G2 = 0.754 -/+ 0.413 (OR=18.3; CI95%: 2.5-133.3; p = 0.006). After adjustment for risk factors for low birth weight, such as smoking, maternal height, bacteriuria, and previous hypertension, the odds ratio for SI dropped to 7.2 (CI95% = 0.4-125.4; P = 0.176). CONCLUSION: The multivariate analysis indicated a marked association between periodontal disease measured by SI score and low birth weight. Our data suggested that periodontal disease during pregnancy may be a risk factor for low weight at birth.

Periodontal disease in pregnancy. 3. Response to local treatment.

(1966). Periodontal Disease in Pregnancy: III. Response to Local Treatment. Acta Odontologica Scandinavica: Vol. 24, No. 6, pp. 747-759.