We present the experimental demonstration of the occurrence of exceptional points of degeneracy (EPDs) in a single resonator by introducing a linear time-periodic variation of one of its components. This is in contrast with the requirement of two coupled resonators with parity time-symmetric systems with precise values of gain and loss. In the proposed scheme, only the tuning of the modulation frequency is required, which is easily achieved in electronic systems. The EPD is a point in a system parameters’ space at which two or more eigenstates coalesce, and this leads to unique properties not occurring at other non-degenerate operating points. We show theoretically and experimentally the existence of a second-order EPD in a time-varying single resonator. Furthermore, we measure the sensitivity of the proposed system to a small structural perturbation and show that the two shifted system’s eigenfrequencies are well detected even for relative perturbations of 0.3%, with distinguished peaks well above the noise floor. We show that the regime of operation of the system at an EPD leads to a unique square-root-like sensitivity, which can devise new exceptionally sensitive sensors based on a single resonator by simply applying time modulation.