Period Of Cycle Research Articles

A multi-wavelength overview of the giant spiral UGC 2885

UGC 2885 ($z = 0.01935$) is one of the largest and most massive galaxies in the local Universe, yet it has an undisturbed spiral structure, which is unexpected for such an object and is not predicted by cosmological simulations. Understanding the detailed properties of extreme systems such as UGC 2885 can provide insight into the limits of scaling relations and the physical processes driving galaxy evolution. Our goal is to understand whether UGC 2885 has followed a similar evolutionary path as other high-mass galaxies by examining its place in the fundamental metallicity relation and on the star-forming main sequence. We present new observations of UGC 2885 with the Canada-France-Hawaii Telescope and the Institut de radioastronomie millimétrique 30 m telescope. We used these novel data to calculate metallicity and molecular hydrogen mass values, respectively. We estimated the stellar mass (M$_ star $) and star formation rate (SFR) based on mid-infrared observations with the Wide-field Infrared Survey Explorer. We find global metallicities $Z = 9.28$, 9.08, and 8.74 at the 25 kpc ellipsoid from the N2O2, R23, and O3N2 indices, respectively. This puts UGC 2885 at the high end of the galaxy metallicity distribution. We find a molecular hydrogen mass of M$_ $ M$_ odot $, a SFR of $1.63 odot $ yr$^ $, and a stellar mass of $4.83 $ M$_ odot $, which gives a star formation efficiency ($ SFR $) of $8.67 $ yr$^ $. This indicates that UGC 2885 has an extremely high molecular gas content compared to known samples of star-forming galaxies ($ times more) and a relatively low SFR for its current gas content. We conclude that UGC 2885 has gone through cycles of star formation periods, which increased its stellar mass and metallicity to its current state. The mechanisms that are fuelling the current molecular gas reservoir and keeping the galaxy from producing stars remain uncertain. We discuss the possibility that a molecular bar is quenching star-forming activity.

The Effects of Global Climate Warming on the Developmental Parameters of Helicoverpa armigera (Hübner, 1808) (Lepidoptera: Noctuidae)

Helicoverpa armigera (Hübner, 1808) is a significant global agricultural pest, particularly posing a major threat during the boll-forming stage of cotton. In recent years, the severity of its damage has increased markedly, and its population dynamics and biological characteristics may be profoundly affected by global climate change. This study conducted a systematic meta-analysis to evaluate the life history traits of H. armigera under conditions of rising global temperatures, different photoperiods, and humidity levels. A comprehensive analysis of 26 related studies revealed that different developmental stages of H. armigera have distinct temperature requirements. When the temperature is within an optimal range (32 °C to 35 °C), the development rate of H. armigera accelerates, the life cycle shortens, and the reproductive capacity of female moths increases. However, when the temperature exceeds 35 °C, development slows, mortality rates increase, and the oviposition of female moths decreases significantly, indicating a negative impact of high temperatures on growth and reproduction. Overall, as the temperature rises above 20 °C, various physiological indicators of H. armigera significantly improve, and at 32 °C, the larval development period and overall life cycle reach their shortest duration. This meta-analysis provides new insights into the biological responses of H. armigera in the context of climate change and offers a scientific basis for future control strategies.

EU Cohesion Policies and interregional inequalities in disruptive times

Despite the numerous contributions assessing the efficiency and effectiveness of Cohesion Policies, their role in stimulating growth and cohesion in different macroeconomic settings and in different business cycle periods remains highly debated. This article aims at contributing to this literature by investigating the link between Cohesion Policy, economic growth and interregional inequalities over periods of crisis and recovery. In particular, the article analyses whether Cohesion Policy is beneficial for the recovery of those regions mostly hit by the crisis and contributes to narrowing interregional gaps enhanced by the crisis. In addition, the paper analyses how the link between Cohesion Policy and interregional inequalities changes by investment axes, as it is the case of Research, Technology Development and Innovation funds, targeted to different goals. Based on an analysis covering all EU27 and UK NUTS2 regions in the period 2008–2019, the article confirms the multifaceted nexus between Cohesion Policy and interregional inequalities. It also raises warnings about the potential conflicts between its overarching goals and its multiple and expanding strategic objectives.

Utilization of Purple Napier Grass Silage on Milk Quality and Blood Antioxidant Activity in Lactating Dairy Goats

In this study, our subjects were 18 female crossbred Saanen lactating goats; the goats weighed approximately 43.25 ± 2.35 kg and had been producing milk for 14 ± 2 days. They were assigned to three equally sized experimental groups based on the cycle of the lactation period. In accordance with the randomized complete block design (RCBD), six animals were randomly assigned to the treatments in each block. There were three treatments: (1) control = Napier Pakchong-1 grass silage (NPS); (2) = sweet grass silage (SGS); and (3) = purple Napier silage (PNS). Our findings show that the goats fed with purple Napier grass silage had a higher DM intake (1805.97 g/day) than those that underwent a different treatment (1312.76 and 1443.43 g/day). The goats fed with purple Napier grass silage had higher protein digestibility (79.85) than those fed with Napier Pakchong-1 and sweet grass silage. There were significant differences in the ruminal ammonia nitrogen and blood urea nitrogen. Nevertheless, purple Napier grass silage significantly increased butyric acid 2 and 4 h after feeding and increased the number of microorganisms. In the dairy goats fed purple Napier grass silage, we observed a reduction in protozoa and methanogen populations. The levels of antioxidants shown by the plasma indices differed in the goats fed with purple Napier grass silage and showed enhanced milk composition, higher levels of total antioxidants, superoxide dismutase and glutathione peroxidase in the plasma, reduced protozoa methanogen, and a decreased level of malondialdehyde in the plasma. This study highlights that purple Napier grass silage has the potential to be a beneficial source of roughage for lactating dairy goats.

Grain-Boundary-Rich Interphases for Rechargeable Batteries.

The formation of stable interphases on the electrodes is crucial for rechargeable lithium (Li) batteries. However, next-generation high-energy batteries face challenges in controlling interphase formation due to the high reactivity and structural changes of electrodes, leading to reduced stability and slow ion transport, which accelerate battery degradation. Here, we report an approach to address these issues by introducing multicomponent grain-boundary-rich interphase that boosts the rapid transport of ions and enhances passivation toward prolonged lifespan. This is guided by fundamental principles of solid-state ionics and geological crystallization differentiation theory, achieved through improved solvation chemistry. Demonstrations showcase how the introduction of the interphase substantially impacts the Li-ion transport across the interphase and the electrode-electrolyte compatibility in cost-effective electrolyte solutions optimized with multiple Li salts. The resulting interphases feature microstructures rich in inorganic grain boundaries with a diverse array of nanosized grains, presenting enhanced Li-ion transport. Comprehensive analyses revealed that this realizes remarkable electrochemical stability over extended cycling periods by inhibiting electrode corrosion, thus holding promise for high-capacity thin-Li-metal, Si-based anodes, and even Li-free anodes when paired with high-capacity oxide cathodes. This work opens new avenues to customize protective interphases on high-capacity electrodes, promoting the development of batteries with the highest energy density using cost-effective electrolytes.

Anion‐Anchored Polymer‐in‐Salt Solid Electrolyte for High‐Performance Zinc Batteries

AbstractSolid polymer electrolytes hold promise for addressing key challenges in rechargeable zinc batteries (ZBs) utilizing aqueous electrolytes. However, achieving simultaneous high ionic conductivity, excellent mechanical strength, and a high cation transference number while effectively suppressing Zn dendrites remains challenging. Herein, we design a novel polymer‐in‐salt solid electrolyte (PISSE) composed of polyacrylonitrile (PAN), zinc chloride (ZnCl2), and niobium pentoxide with oxygen vacancies (Nb2O5‐x) with high ionic conductivity. PAN polymer matrix provides the electrolyte good mechanical properties and solubility of Zn salt. The high concentration of ZnCl2 effectively decouples the Zn2+ from polymer chain segments and provides more ionic conduction amorphous region. Moreover, incorporating Nb2O5‐x filler accelerates Zn2+ desolvation by anchoring (ZnxCly)2x–y clusters and enhances the system's mechanical properties, achieving a superior Zn2+ transference number (~0.93) and interfacial stability. Consequently, the optimized PISSE demonstrates exceptional stability during prolonged cycling periods, wide temperature range operation (−40 °C to 60 °C), remarkable flexibility, and compatibility with diverse electrode materials. This study provides valuable insights into the design of solid‐state electrolytes based on ZBs and elucidates their multifunctional prospects.

Estrogen blood profile of chickens in the studied period of the ovulatory cycle

The aim: to study the dynamics of the concentrations of estradiol, estriol and estrone, their ratios in the studied period of the ovulatory cycle and the connection with the size of egg yolk.Materials and methods. The material for the study was chickens of the Pushkin breed, in the amount of 36 birds. at 36 weeks of age. The chickens were kept in individual cages. Light mode — 14C:10T. Watering — nipple, temperature in the poultry house and feeding - in accordance with the standards adopted by the Central Collective Use Center of the All-Russian Scientific Research Institute of Growing Animals "Genetic collection of rare and endangered breeds of chickens". Over the course of 7 days, eggs from 96 chickens of 30 weeks of age were assessed by the weight of the egg, yolk, white, shell - using electronic scales Mertech M-ER 122ACF(JR) with an accuracy of 0,01 g. Eggs were counted and assessed individually: From each hen, at least 3 consecutively laid eggs were examined the next day after collection. Based on the data obtained from assessing chickens based on the quality characteristics of eggs and productivity, 36 birds with egg yolk weights M-0,5σ, M±0,45σ, M+0,5σ were selected. Blood from the studied chickens was taken in the morning and during the day on an empty stomach to simultaneously determine the concentrations of estradiol, estriol and estrone 2 hours before laying eggs and within 4 hours after laying, with an interval of 1 hour. In order to obtain serial blood samples from chickens for Dynamic studies of estrogens included the installation of peripheral venous (intravenous) catheters. The concentration of estrogen in the blood plasma of chickens was determined by ELISA.Results. The concentrations of individual estrogenic hormones change during the 6 hours of the studied period of the ovulatory cycle, periodically increasing and decreasing, while the fluctuations coincide only in two periods after the egg is laid: after 1—2 hours — a rise and 2—3 hours — a decline. Of the six studied periods of the ovulatory cycle of chickens, the time period of practical interest is 2—1 hours before egg laying, when the ratio of estradiol:estrone was 7,4:1, estriol:estrone — 7,9:1 and estradiol:estriol — 1:1. During this period, a positive significant correlation was revealed between the estradiol:estrone ratio and the yolk mass of chicken eggs — +0,55 (p <0,05). Also, in the established period, the highest concentration of estradiol (1,52±0,12 nmol/l), estrone (0,29±0,04 nmol/l) was simultaneously observed compared to other periods, and the lowest concentration of estriol (1,67± 0,16 nmol/l). A positive correlation was determined between estradiol and estrone — +0,68 (p <0,05) and estradiol and estriol — +0,71 (p <0,05).Conclusion. In the period 2—1 hours before laying eggs, the effect on the body of chickens of estrogenic hormones in the ratio estradiol: estrone 7,4:1, estriol:estrone – 7,9:1 and estradiol:estriol — 1:1 leads to inactivation of synthetic systems, providing intensive formation of ovogenic substances by the liver (vitellogenin, lipoproteins), and the transfer of vitellogenic material into developing follicles.

Study on micromechanical behavior and energy evolution of granular material generated by latent diffusion model under rotation of principal stresses

In this study, advanced image processing technology is used to analyze the three-dimensional sand composite image, and the topography features of sand particles are successfully extracted and saved as high-quality image files. These image files were then trained using the latent diffusion model (LDM) to generate a large number of sand particles with real morphology, which were then applied to numerical studies. The effects of particle morphology on the macroscopic mechanical behavior and microscopic energy evolution of sand under complex stress paths were studied in detail, combined with the circular and elliptical particles widely used in current tests. The results show that with the increase of the irregularity of the sample shape, the cycle period and radius of the closed circle formed by the partial strain curve gradually decrease, and the center of the circle gradually shifts. In addition, the volume strain and liquefaction strength of sand samples increase with the increase of particle shape irregularity. It is particularly noteworthy that obvious vortex structures exist in the positions near the center where deformation is severe in the samples of circular and elliptical particles. However, such structures are difficult to be directly observed in sample with irregular particles. This phenomenon reveals the influence of particle morphology on the complexity of the mechanical behavior of sand, providing us with new insights into the understanding of the response mechanism of sand soil under complex stress conditions.

A Possible Explanation of W-type Phenomena in V694 Peg

Three sets of complete multicolor light curves of V694 Peg observed in 2013, 2015, and 2019 were presented and analyzed. Our photometric solutions show that this system was an A-type shallow contact binary in 2013 and 2015 while it converted to a W-type one in 2019. A large cool spot on the component of this binary could explain the conversion, implying the W-type phenomena may be caused by the magnetic activity of the components. We have collected available data on this binary and calculated 505 times of light minimum, which spans 17 yr. The orbital period investigation based on these timings shows there is a long-term period increase at a rate of dP/dt = 4.3(±0.3)×10−9 day yr−1 superposed on a periodic variation with a period of 11.81(±0.06) yr. The cyclic orbital variation may be the result of magnetic activity cycles or the existence of a third body. Until now, only eight transformed systems, including V694 Peg, have been reported. Compared with other converting contact systems between A-type and W-type, V694 Peg is recorded as the shortest-period one. All of these converting systems are late-type (later than F7) contact binaries with the O’Connell effect and show cyclic period variation, which indicates that magnetic activity may be the reason for the conversion between the two types of contact binaries. For investigating the nature of A-type and W-type phenomena, the discovery of more converting contact binaries is essential.

Statistical inference with a manifold-constrained RNA velocity model uncovers cell cycle speed modulations.

Across biological systems, cells undergo coordinated changes in gene expression, resulting in transcriptome dynamics that unfold within a low-dimensional manifold. While low-dimensional dynamics can be extracted using RNA velocity, these algorithms can be fragile and rely on heuristics lacking statistical control. Moreover, the estimated vector field is not dynamically consistent with the traversed gene expression manifold. To address these challenges, we introduce a Bayesian model of RNA velocity that couples velocity field and manifold estimation in a reformulated, unified framework, identifying the parameters of an explicit dynamical system. Focusing on the cell cycle, we implement VeloCycle to study gene regulation dynamics on one-dimensional periodic manifolds and validate its ability to infer cell cycle periods using live imaging. We also apply VeloCycle to reveal speed differences in regionally defined progenitors and Perturb-seq gene knockdowns. Overall, VeloCycle expands the single-cell RNA sequencing analysis toolkit with a modular and statistically consistent RNA velocity inference framework.

Human short-latency reflexes show precise short-term gain adaptation after prior motion.

The central nervous system adapts the gain of short-latency reflex loops to changing conditions. Experiments on biomimetic robots showed that reflex modulation could substantially increase energy efficiency and stability of periodic motions if, unlike known mechanisms, the reflex modulation both acted precisely on the muscles involved and lasted after the motion. This study tests the presence of such a mechanism by having participants repeatedly rotate either their right elbow or shoulder joint, before perturbing either joint. The results demonstrate a mechanism that modulates short-latency reflex gains after prior motion with joint-specific precision. Enhanced gains were observed hundreds of milliseconds after movement cessation, a time scale well-suited to quickly adapt overall periodic motion cycles. A serotonin antagonist significantly decreased these post-movement gains diffusely across joints. But blocking serotonin did not affect the joint-specificity of the gain scaling more than a placebo, suggesting that serotonin sets the overall reflex gain across joints after movement by an effect that is modulated in a joint-specific manner by an unidentified neural circuit. These results confirm the existence of a new, joint-specific, fast, persistent adaptation of short-latency reflex loops induced by motion in human arms.

European Association for the Study of Obesity (EASO) Position Statement on Medical Nutrition Therapy for the Management of Individuals with Overweight or Obesity and Cancer.

Obesity, a prevalent and multifactorial disease, is linked to a range of metabolic abnormalities, including insulin resistance, dyslipidemia, and chronic inflammation. These imbalances not only contribute to cardiometabolic diseases but also play a significant role in cancer pathogenesis. The rising prevalence of obesity underscores the need to investigate dietary strategies for effective weight management for individuals with overweight or obesity and cancer. This European Society for the Study of Obesity (EASO) position statement aimed to summarize current evidence on the role of obesity in cancer and to provide insights on the major nutritional interventions, including the Mediterranean diet (MedDiet), the ketogenic diet (KD), and the intermittent fasting (IF), that should be adopted to manage individuals with overweight or obesity and cancer. The MedDiet, characterized by high consumption of plant-based foods and moderate intake of olive oil, fish, and nuts, has been associated with a reduced cancer risk. The KD and the IF are emerging dietary interventions with potential benefits for weight loss and metabolic health. KD, by inducing ketosis, and IF, through periodic fasting cycles, may offer anticancer effects by modifying tumor metabolism and improving insulin sensitivity. Despite the promising results, current evidence on these dietary approaches in cancer management in individuals with overweight or obesity is limited and inconsistent, with challenges including variability in adherence and the need for personalized dietary plans.

Parameters Optimization for Improving Bioluminescence Inhibition Assay Using Vibrio fischeri Bacteria to Detect Lipopolysaccharide Toxicity in Aquatic Environments.

Bioluminescence inhibition of Vibrio fischeri is a widely used method for toxicity testing in aquatic environments. Certain complex biological contaminants, such as lipopolysaccharide (LPS), can interfere with metabolic pathways during toxicity assays. The standard 15-minute Vibrio fischeri bioluminescence assay has limitations when evaluating and screening water toxicity against complex and emerging chemicals like LPS. To accurately determine the effects of such substances, it is crucial to use a bioassay that encompasses a sufficient cell cycle period. This study tested LPS at varying incubation times (ranging from 60s to 60min) and concentrations (1-1*10- 12 mg/ml) to identify the appropriate incubation time for bioluminescence inhibition and toxicity testing. The results indicated that bioluminescence inhibition begins within 60s and reaches maximum inhibition at 60min. However, at 30 and 45min, the bacterial response to different concentrations of LPS varied, with some concentrations causing increased bioluminescence. The EC50 values at different times (60s, 15, 30, 45, and 60min) were found to be 0.0012, 0.0063, 4.07e + 54, 3.85e-8, and 3.34e-9mg/ml respectively. This study highlights the importance of considering incubation time when using bioluminescence inhibition to detect acute toxicity in aquatic ecosystems. A longer incubation time may enhance the method's sensitivity and improve its ability to detect low levels of toxins, such as LPS, in water resources.

The evolution of spatial and temporal distribution of rainfall erosivity in Henan Province, central China

With the advancement of urbanization, there has been a significant reduction in cultivated land, accompanied by soil erosion. Concurrently, the regularity of rainfall in recent years has been erratic, adversely impacting the grain economy and agricultural development in certain regions. Henan Province, spanning the basins of the Yangtze River, the Yellow River, the Huaihe River, and the Haihe River, possesses complex hydrological conditions and serves as a pivotal agricultural zone in China. Therefore, this paper utilizes daily rainfall data collected over 54 years (1969–2022) from 112 rain measuring stations in Henan Province to calculate the rainfall erosivity using the Zhang model and the erosivity model from the first national water survey. Meanwhile, spatial analysis was performed using the Kriging interpolation method in the ArcGIS Geostatistical Wizard, resulting in detailed spatial distribution maps of rainfall and rainfall erosivity. The study also employed Wavelet and Mann–Kendall tests to analyze the abrupt changes, trends and periodicity of rainfall and rainfall erosivity within the target region. The findings indicate that the average rainfall (1969–2022) in Henan province was 718.26 mm, while the average rainfall erosivity (R) was 3213.46 MJ mm/(hm2 h). R values are positively correlated with rainfall intensity and volume, displaying an annual upward trend. Spatially, R values increase gradually from northwest to southeast, closely aligning with topographical variations. Additionally, the analysis revealed a predominant periodic cycle of 54 years in the precipitation patterns. These results offer valuable insights for environmental and agricultural management in other regions of central China.

Stawanie się miejskim rowerzystą. Biografie mobilności dojeżdżających do pracy rowerem

This article presents the results of semi-structured interviews with eight individuals whose primary or significant mode of transportation in the city is the bicycle. The purpose of the analysis was to describe the trajectory of becoming an urban cyclist. During the interview, three stages of bicycle use emerged: childhood, high school, and college and work. These stages were somewhat more clearly separated by interviewees, who were also able to distinguish periods of cycling and noncycling. At the same time, the beginning of a new stage may represent one of the key moments when survey participants may give up cycling (especially the start of high school) or take up the activity anew (e.g., children entering a period of greater independence). In addition, the start of cycling for transportation purposes may be easier to think about for those accustomed to physical activity, and especially for those cycling for recreational or sporting purposes. The city’s bike-sharing system can be a significant factor in initiating the practice of cycling for people who did not own bicycles and/or have not used them for many years.

From ‘strong recommendation’ to practice: A pre-test post-test study examining adherence to stroke guidelines for fever, hyperglycaemia, and swallowing (FeSS) management post-stroke

BackgroundThe Quality in Acute Stroke Care (QASC) Trial demonstrated that assistance to implement protocols to manage Fever, hyperglycaemia (Sugar) and Swallowing (FeSS) post-stroke reduced death and disability. In 2017, a ‘Strong Recommendation’ for use of FeSS Protocols was included in the Australian Clinical Guidelines for Stroke Management. We aimed to: i) compare adherence to FeSS Protocols pre- and post-guideline inclusion; ii) determine if adherence varied with prior participation in a treatment arm of a FeSS Intervention study, or receiving treatment in a stroke unit; and compare findings with our previous studies. MethodsPre-test post-test study using Australian acute stroke service audit data comparing 2015/2017 (pre-guideline) versus 2019/2021 (post-guideline) adherence. Primary outcome was adherence to all six FeSS indicators (composite), with mixed-effects logistic regression adjusting for age, sex, stroke type and severity (ability to walk on admission), stroke unit care, hospital prior participation in a FeSS Intervention study, and correlation of outcomes within hospital. Additional analysis examined interaction effects. ResultsOverall, 112 hospitals contributed data to ≥1 one Audit cycle for both periods (pre=7011, post=7195 cases); 42 hospitals had participated in any treatment arm of a FeSS Intervention study. Adherence to FeSS Protocols post-guideline increased (pre: composite measure 35% vs post: composite measure 40 %, aOR:1.2 95 %CI: 1.2, 1.3). Prior participation in a FeSS Intervention study (aOR:1.6, 95 %CI: 1.2, 2.0) and stroke unit care (aOR 2.3, 95 %CI: 2.0, 2.5) were independently associated with greater adherence to FeSS Protocols. There was no change in adherence over time based on prior participation in a FeSS Intervention study (p = 0.93 interaction), or stroke unit care (p = 0.07 interaction). ConclusionsThere is evidence of improved adherence to FeSS Protocols following a ‘strong recommendation’ for their use in the Australian stroke guidelines. Change in adherence was similar independent of hospital prior participation in a FeSS Intervention study, or stroke unit care. However, maintenance of higher pre-guideline adherence for hospitals prior participation in a FeSS Intervention study suggests that research participation can facilitate greater guideline adherence; and confirms superior care received in stroke units. Nevertheless, less than half of Australian patients are being cared for according to the FeSS Protocols, providing impetus for additional strategies to increase uptake.

Impact of antral follicle count on follicular-luteal characteristics, superovulatory response, and embryo quality in Sahiwal cows.

The study aimed to evaluate the effect of antral follicle count (AFC) on follicular and luteal development during the estrous cycle and superovulatory period, as well as on superovulatory response and in vivo embryo quality within the MOET program. A total of 48 estrus-induced (500 μg PGF2α, Single dose, IM) Sahiwal cows (Bos indicus) with a BCS between 3.5 and 4.0 were selected for the study. On the day of wave emergence, the animals were divided into two groups based on the AFC, i.e., low AFC (≤18) and high AFC (>18). Both the groups were monitored daily using B-mode ultrasonography (USG) for one cycle, and the superovulation protocol was initiated on the 9th day of the subsequent estrous cycle. A total of 240 μg of FSH in eight divided doses were given in a tapering sequence for 4 days and simultaneous administration of 500 μg PGF2α, along with the fifth dose of FSH. Donors were inseminated at superovulatory estrus using double straws of high-quality frozen semen thrice at 12-h intervals, and non-surgical flushing was performed on day 7 of the superovulatory estrus followed by embryo searching and evaluation under a stereo zoom microscope. Ovulatory waves of the high-AFC Sahiwal cows have significantly (p ≤ 0.05) larger sizes of preovulatory follicles (POF) (12.06 ± 0.19 mm vs 11.56 ± 0.16 mm) and corpus luteum (CL) (19.57 ± 0.28 mm vs 18.26 ± 0.35 mm), as compared to low AFC. The ovarian size was significantly (p < 0.0001) larger in cows with high AFC during the superovulatory protocol. The number of large, medium, and small follicles was significantly (p < 0.0001) high on the day of superovulatory estrus (SOE), PGF2α administration, and initiation of superovulatory protocol, respectively, in high AFC. Donors with high AFC had a notably greater (p < 0.0001) count of CL and embryos retrieved per flushing, including excellent and fair-quality embryos. A strong association (p < 0.0001) between high AFC and ovarian size (r = 0.9136), superovulatory response (r = 0.9350), and embryo quality (x2 = 8.788; p = 0.032) and number (r = 0.9858) were also recorded. Based on these results, AFC is considered a dependable indicator for forecasting reproductive capacity. Bos indicus donors with an average AFC of 30 or higher are recommended.

A 650-Myr history of Earth's axial precession frequency and the evolution of the Earth-Moon system derived from cyclostratigraphy.

The preservation of Milankovitch cycles in the stratigraphic record provides independent geological information to study our ancient solar system and can be leveraged to constrain existing theoretical models. Here, we identify 34 high-quality cyclostratigraphic records spanning the past 650 million years and use them to infer the evolution of the Earth-Moon system through a Bayesian inversion method. We reconstruct the time evolution of Earth's axial precession frequency, lunar distance, length of day, and the periods of obliquity and climatic precession cycles. The results indicate an interval of high tidal energy dissipation in the Earth-Moon system at ~300 to 200 million years ago, and are broadly consistent with an independently calculated tidal evolution model. Our results provide an improved determination of the past periods of obliquity and climatic precession for astrochronology applications and yield important constraints on the history of tidal energy dissipation during the Phanerozoic Eon.

A mathematical model of Cheyne-Stokes or periodic breathing

Cheyne-Stokes Breathing is a periodic cycle of apnea followed by hyperventilation. A theory of this phenomenon is developed based on a minimal set of physiological assumptions. The rate of loss of CO2 from venous blood is proportional to the CO2 concentration in the lungs times the respiration rate; the respiration rate is a linear function of arterial CO2 concentration above a threshold, and zero below that threshold. A time delay between blood in lungs and respiratory response allows the system to go into oscillation. These assumptions lead to a single nonanalytic delay-differential equation containing only three parameters, which we call respiratory recovery coefficients, (α,β,γ). A detailed study of the solutions to this equation is presented here. For β below a first threshold, breathing becomes steady, and any disturbance recovers exponentially to the steady state (∼overdamped oscillator). Above the first threshold, breathing recovers to the steady state by decaying oscillations (∼underdamped oscillator). Above a second threshold, oscillations grow to reach a limit cycle, and when that cycle is sufficiently large, it represents the Cheyne-Stokes cycle of hyperventilation and apnea. Fourier analysis shows that the transition to growing oscillations is a forward or soft Hopf bifurcation. In the Cheyne-Stokes region (sufficiently large β), the equation predicts the shapes of the curves representing the time-dependence of arterial CO2 and the respiration rate. From these shapes, we infer the values of the respiratory recovery coefficients for several groups of patients. With additional approximations, we infer the values of other physiological parameters, including cardiac output, CO2 chemosensitivity, and volume of blood between lungs and detectors.

Magnetohydrodynamic simulations of A-type stars: Long-term evolution of core dynamo cycles

Early-type stars have convective cores due to a steep temperature gradient produced by the CNO cycle. These cores can host dynamos and the generated magnetic fields may be relevant in explaining the magnetism observed in Ap/Bp stars. Our main objective is to characterise the convective core dynamos and differential rotation. We aim to carry out the first quantitative analysis of the relation between magnetic activity cycle and rotation period. We used numerical 3D star-in-a-box simulations of a $2.2 M_ A-type star with a convective core of roughly 20&lt;!PCT!&gt; of the stellar radius surrounded by a radiative envelope. We explored rotation rates from 8 to 20 days and used two models of the whole star, along with an additional zoom set where 50&lt;!PCT!&gt; of the radius was retained. The simulations produce hemispheric core dynamos with cycles and typical magnetic field strengths around $60$ kG. However, only a very small fraction of the magnetic energy is able to reach the surface. The cores have solar-like differential rotation and a substantial part of the radiative envelope has a quasi-rigid rotation. In the most rapidly rotating cases, the magnetic energy in the core is roughly 40&lt;!PCT!&gt; of the kinetic energy. Finally, we find that the magnetic cycle period, $P_ cyc $, increases with decreasing the rotation period, $P_ rot $, which has also been observed in many simulations of solar-type stars. Our simulations indicate that a strong hemispherical core dynamo arises routinely, but that it is not enough the explain the surface magnetism of Ap/Bp stars. Nevertheless, since the core dynamo produces dynamically relevant magnetic fields, it should not be neglected even when other mechanisms are being explored.