Periarticular Inflammation Research Articles

Treatment with colchicine if the periarticular inflammation associated with sarcoidosis: a need for continued appraisal

Arthritis & RheumatismVolume 14, Issue 1 p. 130-133 CommunicationFree to Read Treatment with colchicine if the periarticular inflammation associated with sarcoidosis: a need for continued appraisal Edward D. Harris JR MD, Edward D. Harris JR MD Hanover, New HampshireSearch for more papers by this authorMichael Millis MD, Michael Millis MD Cleveland, OhioSearch for more papers by this author Edward D. Harris JR MD, Edward D. Harris JR MD Hanover, New HampshireSearch for more papers by this authorMichael Millis MD, Michael Millis MD Cleveland, OhioSearch for more papers by this author First published: January/February 1971 https://doi.org/10.1002/art.1780140117Citations: 6AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume14, Issue1January/February 1971Pages 130-133 RelatedInformation

Periarticular inflammation, bilateral hilar adenopathy and a sarcoid reaction.

AbstractA total of 19 cases of bilateral hilar adenopathy in association with polyarthritis are presented. Erythema nodosum, usually occurring in this syndrome, was not present; however, marked periarticular inflammation of the ankles with little pain on motion was noted and served as the initial clue to the diagnosis. All patients had elevated sedimentation rates; hyperglobulinemia and positive tests for rheumatoid factor were frequently found. A sarcoid reaction was seen in 73% of the patients whose tissue was examined histologically. Diagnosis was established by the radiologic demonstration of bilateral hilar adenopathy. Prognosis was favorable. The etiology of the disorder is unknown, and its relationship to Boeck's sarcoidosis Is uncertaian.

Crystal-induced inflammation associated with chronic renal failure treated with periodic hemodialysis

Acute episodes of articular and periarticular inflammation occurred in a patient receiving periodic hemodialysis twice weekly for chronic renal failure. Musculoskeletal symptoms, articular in location, appeared prior to dialysis therapy. Further symptoms, mainly periarticular and para-articular in location, were observed after hemodialysis was begun and appeared to develop in association with metastatic calcification not previously noted. The upper extremities were primarily involved. Response to colchicine therapy was consistently good whether the attacks were articular or paraarticular in location. Analysis of soft tissue crystalline material by x-ray and electron diffraction technics revealed calcium apatite but no urates or pyrophosphates. Increase in dialysis time to three times a week was not associated with reduction of serum uric acid and phosphorus levels or with clinical improvement of musculoskeletal symptoms or significant reduction of tissue calcium deposition as observed on roentgenograms. Treatment with aluminum hydroxide gel resulted in a significant reduction of serum phosphorus levels with associated clinical and roentgenologic improvement even when dialysis time was reduced to a twice weekly schedule. Reduction of antacid therapy was promptly followed by increased symptoms and new areas of metastatic calcification. No specific relationship was noted between serum uric acid levels and the degree of clinical symptoms or metastatic calcifications. The clinical syndrome observed appeared to present features which were atypical for gout. The clinical course, crystal analysis and response to therapy suggest that inflammatory episodes in this syndrome following institution of periodic hemodialysis occur as a response to soft tissue calcifications which develop in relationship to dialysis therapy.

ACUTE PERI-ARTICULAR INFLAMMATION INDUCED IN RATS BY ORAL 6-SULFANILYLINDAZOLE.

ACUTE PERI-ARTICULAR INFLAMMATION INDUCED IN RATS BY ORAL 6-SULFANILYLINDAZOLE.

Further observations on the treatment of bursitis of the shoulder

1. 1. The most common condition found in the painful shoulder is bursitis. 2. 2. Primary bacterial inflammation is rare in subacromial bursae. 3. 3. Subacromial bursitis is nearly always secondary to injury of a neighboring structure. 4. 4. Calcification can be demonstrated in about four out of five cases of bursitis of the shoulder. 5. 5. Calcification in the five main tendons about the shoulder may eventually occur if they have been subjected to wear and tear or repeated small injuries. 6. 6. The severity of the symptoms associated with bursitis is not in proportion to the amount of calcification present. 7. 7. No treatment of a painful shoulder should be undertaken until x-rays have been studied. The oblique projection is strongly recommended. 8. 8. Irrigation of the bursa is indicated in a large majority of acute cases. It is, however, definitely contraindicated in periarticular inflammation and all conditions of doubtful etiology. 9. 9. Both shoulders should never be irrigated, stretched or operated upon at the same time. 10. 10. The irrigation procedure is always best carried out in the hospital.