1. 1. We feel that the prophylactic treatment consisting of hypodermic injections of alcoholic extract of Rhus toxicodendron have been quite satisfactory. 2. 2. The material given in gradually increasing doses did not cause any generalized eruption or any local discomfort. 3. 3. The annoying pruritus ani and perianal dermatitis were entirely lacking. 4. 4. No member of the group was incapacitated because of Rhus dermatitis.